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Journal Abstract Search

166 related items for PubMed ID: 32381

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  • 4. Covalent binding of metabolites of 4-ipomeanol to rabbit pulmonary and hepatic microsomal proteins and to the enzymes of the pulmonary cytochrome P-450-dependent monooxygenase system.
    Slaughter SR, Statham CN, Philpot RM, Boyd MR.
    J Pharmacol Exp Ther; 1983 Jan; 224(1):252-7. PubMed ID: 6848746
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  • 5. Monooxygenase-mediated activation of chlorotrianisene (TACE) in covalent binding to rat hepatic microsomal proteins.
    Juedes MJ, Bulger WH, Kupfer D.
    Drug Metab Dispos; 1987 Jan; 15(6):786-93. PubMed ID: 2893703
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  • 6. Renal toxicity due to reactive metabolites formed in situ in the kidney: investigations with 4-ipomeanol in the mouse.
    Boyd MR, Dutcher JS.
    J Pharmacol Exp Ther; 1981 Mar; 216(3):640-6. PubMed ID: 7205642
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  • 7. Phenytoin metabolic activation: role of cytochrome P-450, glutathione, age, and sex in rats and mice.
    Roy D, Snodgrass WR.
    Res Commun Chem Pathol Pharmacol; 1988 Feb; 59(2):173-90. PubMed ID: 3358010
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  • 10. In vitro metabolic activation of the pulmonary toxin, 4-ipomeanol, in nonciliated bronchiolar epithelial (Clara) and alveolar type II cells isolated from rabbit lung.
    Devereux TR, Jones KG, Bend JR, Fouts JR, Statham CN, Boyd MR.
    J Pharmacol Exp Ther; 1982 Jan; 220(1):223-7. PubMed ID: 7053419
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  • 11. Activation of 14C-toluene to covalently binding metabolites by rat liver microsomes.
    Pathiratne A, Puyear RL, Brammer JD.
    Drug Metab Dispos; 1986 Jan; 14(4):386-91. PubMed ID: 2873983
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  • 12. CYP4B1 activates 4-ipomeanol in rat lung.
    Verschoyle RD, Philpot RM, Wolf CR, Dinsdale D.
    Toxicol Appl Pharmacol; 1993 Dec; 123(2):193-8. PubMed ID: 8248926
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  • 13. Hepatic and pulmonary microsomal metabolism of naphthalene to glutathione adducts: factors affecting the relative rates of conjugate formation.
    Buckpitt AR, Bahnson LS, Franklin RB.
    J Pharmacol Exp Ther; 1984 Nov; 231(2):291-300. PubMed ID: 6491983
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  • 14. In vitro studies on the metabolic activation of the furanopyridine L-754,394, a highly potent and selective mechanism-based inhibitor of cytochrome P450 3A4.
    Sahali-Sahly Y, Balani SK, Lin JH, Baillie TA.
    Chem Res Toxicol; 1996 Sep; 9(6):1007-12. PubMed ID: 8870989
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  • 15. Comparison of ratios of covalent binding to total metabolism of the pulmonary toxin, 4-ipomeanol, in vitro in pulmonary and hepatic microsomes, and the effects of pretreatments with phenobarbital or 3-methylcholanthrene.
    Boyd MR, Sasame HA, Franklin RB.
    Biochem Biophys Res Commun; 1980 Apr 29; 93(4):1167-72. PubMed ID: 7396903
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  • 17. Enzyme-mediated covalent binding of hydralazine to rat liver microsomes.
    Streeter AJ, Timbrell JA.
    Drug Metab Dispos; 1983 Apr 29; 11(3):179-83. PubMed ID: 6135572
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  • 20. Mechanism for isaxonine hepatitis. I. Metabolic activation by mouse and human cytochrome P-450.
    Lettéron P, Fouin-Fortunet H, Tinel M, Danan G, Belghiti J, Pessayre D.
    J Pharmacol Exp Ther; 1984 Jun 29; 229(3):845-50. PubMed ID: 6547179
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