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864 related items for PubMed ID: 32413586

  • 1. Human islets contain a subpopulation of glucagon-like peptide-1 secreting α cells that is increased in type 2 diabetes.
    Campbell SA, Golec DP, Hubert M, Johnson J, Salamon N, Barr A, MacDonald PE, Philippaert K, Light PE.
    Mol Metab; 2020 Sep; 39():101014. PubMed ID: 32413586
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  • 2. Dapagliflozin promotes beta cell regeneration by inducing pancreatic endocrine cell phenotype conversion in type 2 diabetic mice.
    Wei R, Cui X, Feng J, Gu L, Lang S, Wei T, Yang J, Liu J, Le Y, Wang H, Yang K, Hong T.
    Metabolism; 2020 Oct; 111():154324. PubMed ID: 32712220
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  • 3. CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.
    Abels M, Riva M, Bennet H, Ahlqvist E, Dyachok O, Nagaraj V, Shcherbina L, Fred RG, Poon W, Sörhede-Winzell M, Fadista J, Lindqvist A, Kask L, Sathanoori R, Dekker-Nitert M, Kuhar MJ, Ahrén B, Wollheim CB, Hansson O, Tengholm A, Fex M, Renström E, Groop L, Lyssenko V, Wierup N.
    Diabetologia; 2016 Sep; 59(9):1928-37. PubMed ID: 27338624
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  • 4. Processing of proglucagon to GLP-1 in pancreatic α-cells: is this a paracrine mechanism enabling GLP-1 to act on β-cells?
    Whalley NM, Pritchard LE, Smith DM, White A.
    J Endocrinol; 2011 Oct; 211(1):99-106. PubMed ID: 21795304
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  • 5. Intra-islet glucagon confers β-cell glucose competence for first-phase insulin secretion and favors GLP-1R stimulation by exogenous glucagon.
    Cabrera O, Ficorilli J, Shaw J, Echeverri F, Schwede F, Chepurny OG, Leech CA, Holz GG.
    J Biol Chem; 2022 Feb; 298(2):101484. PubMed ID: 34896391
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  • 6. Activation of Transmembrane Bile Acid Receptor TGR5 Modulates Pancreatic Islet α Cells to Promote Glucose Homeostasis.
    Kumar DP, Asgharpour A, Mirshahi F, Park SH, Liu S, Imai Y, Nadler JL, Grider JR, Murthy KS, Sanyal AJ.
    J Biol Chem; 2016 Mar 25; 291(13):6626-40. PubMed ID: 26757816
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  • 7. A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets.
    Marchetti P, Lupi R, Bugliani M, Kirkpatrick CL, Sebastiani G, Grieco FA, Del Guerra S, D'Aleo V, Piro S, Marselli L, Boggi U, Filipponi F, Tinti L, Salvini L, Wollheim CB, Purrello F, Dotta F.
    Diabetologia; 2012 Dec 25; 55(12):3262-72. PubMed ID: 22965295
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  • 8. Pancreatic alpha cells in diabetic rats express active GLP-1 receptor: Endosomal co-localization of GLP-1/GLP-1R complex functioning through intra-islet paracrine mechanism.
    Nakashima K, Kaneto H, Shimoda M, Kimura T, Kaku K.
    Sci Rep; 2018 Feb 27; 8(1):3725. PubMed ID: 29487355
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  • 14. Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetes.
    Omar BA, Liehua L, Yamada Y, Seino Y, Marchetti P, Ahrén B.
    Diabetologia; 2014 Sep 27; 57(9):1876-83. PubMed ID: 24939431
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  • 17. Immunohistochemical assessment of glucagon-like peptide 1 receptor (GLP-1R) expression in the pancreas of patients with type 2 diabetes.
    Kirk RK, Pyke C, von Herrath MG, Hasselby JP, Pedersen L, Mortensen PG, Knudsen LB, Coppieters K.
    Diabetes Obes Metab; 2017 May 27; 19(5):705-712. PubMed ID: 28094469
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  • 20. Localization of dipeptidyl peptidase-4 (CD26) to human pancreatic ducts and islet alpha cells.
    Augstein P, Naselli G, Loudovaris T, Hawthorne WJ, Campbell P, Bandala-Sanchez E, Rogers K, Heinke P, Thomas HE, Kay TW, Harrison LC.
    Diabetes Res Clin Pract; 2015 Dec 27; 110(3):291-300. PubMed ID: 26515908
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