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182 related items for PubMed ID: 32446927

  • 1. Anti-breast cancer and toxicity studies of total secondary saponin from Anemone raddeana Rhizome on MCF-7 cells via ROS generation and PI3K/AKT/mTOR inactivation.
    Zhang D, Zhang Q, Zheng Y, Lu J.
    J Ethnopharmacol; 2020 Sep 15; 259():112984. PubMed ID: 32446927
    [Abstract] [Full Text] [Related]

  • 2. A new discovery: Total Bupleurum saponin extracts can inhibit the proliferation and induce apoptosis of colon cancer cells by regulating the PI3K/Akt/mTOR pathway.
    Zhang X, Liu Z, Chen S, Li H, Dong L, Fu X.
    J Ethnopharmacol; 2022 Jan 30; 283():114742. PubMed ID: 34655668
    [Abstract] [Full Text] [Related]

  • 3. Ginsenoside Rk1 induces cell cycle arrest and apoptosis in MDA-MB-231 triple negative breast cancer cells.
    Hong Y, Fan D.
    Toxicology; 2019 Apr 15; 418():22-31. PubMed ID: 30797898
    [Abstract] [Full Text] [Related]

  • 4. Piper nigrum ethanolic extract rich in piperamides causes ROS overproduction, oxidative damage in DNA leading to cell cycle arrest and apoptosis in cancer cells.
    de Souza Grinevicius VM, Kviecinski MR, Santos Mota NS, Ourique F, Porfirio Will Castro LS, Andreguetti RR, Gomes Correia JF, Filho DW, Pich CT, Pedrosa RC.
    J Ethnopharmacol; 2016 Aug 02; 189():139-47. PubMed ID: 27178634
    [Abstract] [Full Text] [Related]

  • 5. Apoptosis induced by the methanol extract of Salvia miltiorrhiza Bunge in non-small cell lung cancer through PTEN-mediated inhibition of PI3K/Akt pathway.
    Ye YT, Zhong W, Sun P, Wang D, Wang C, Hu LM, Qian JQ.
    J Ethnopharmacol; 2017 Mar 22; 200():107-116. PubMed ID: 28088493
    [Abstract] [Full Text] [Related]

  • 6. PDB-1 from Potentilla discolor Bunge induces apoptosis and autophagy by downregulating the PI3K/Akt/mTOR signaling pathway in A549 cells.
    Zhang RR, Meng NN, Liu C, Li KL, Wang MX, Lv ZB, Chen SY, Guo X, Wang XK, Wang Q, Sun JY.
    Biomed Pharmacother; 2020 Sep 22; 129():110378. PubMed ID: 32544818
    [Abstract] [Full Text] [Related]

  • 7. Ethyl acetate extract from Selaginella doederleinii Hieron inhibits the growth of human lung cancer cells A549 via caspase-dependent apoptosis pathway.
    Sui Y, Li S, Shi P, Wu Y, Li Y, Chen W, Huang L, Yao H, Lin X.
    J Ethnopharmacol; 2016 Aug 22; 190():261-71. PubMed ID: 27292193
    [Abstract] [Full Text] [Related]

  • 8. Anti-proliferative and pro-apoptotic activities of Alpinia oxyphylla on HepG2 cells through ROS-mediated signaling pathway.
    Zhang Q, Cui C, Chen CQ, Hu XL, Liu YH, Fan YH, Meng WH, Zhao QC.
    J Ethnopharmacol; 2015 Jul 01; 169():99-108. PubMed ID: 25891473
    [Abstract] [Full Text] [Related]

  • 9. Anti-proliferative effect of RCE-4 from Reineckia carnea on human cervical cancer HeLa cells by inhibiting the PI3K/Akt/mTOR signaling pathway and NF-κB activation.
    Bai C, Yang X, Zou K, He H, Wang J, Qin H, Yu X, Liu C, Zheng J, Cheng F, Chen J.
    Naunyn Schmiedebergs Arch Pharmacol; 2016 Jun 01; 389(6):573-84. PubMed ID: 26935715
    [Abstract] [Full Text] [Related]

  • 10. Cimicifuga dahurica extract inhibits the proliferation, migration and invasion of breast cancer cells MDA-MB-231 and MCF-7 in vitro and in vivo.
    Jia H, Wang X, Liu W, Qin X, Hu B, Ma Q, Lv C, Lu J.
    J Ethnopharmacol; 2021 Sep 15; 277():114057. PubMed ID: 33771643
    [Abstract] [Full Text] [Related]

  • 11. Combination treatment of ligustrazine piperazine derivate DLJ14 and adriamycin inhibits progression of resistant breast cancer through inhibition of the EGFR/PI3K/Akt survival pathway and induction of apoptosis.
    Chen J, Wang W, Wang H, Liu X, Guo X.
    Drug Discov Ther; 2014 Feb 15; 8(1):33-41. PubMed ID: 24647156
    [Abstract] [Full Text] [Related]

  • 12. Induction of apoptosis in MDA-MB-231 human breast carcinoma cells with an ethanol extract of Cyperus rotundus L. by activating caspases.
    Park SE, Shin WT, Park C, Hong SH, Kim GY, Kim SO, Ryu CH, Hong SH, Choi YH.
    Oncol Rep; 2014 Dec 15; 32(6):2461-70. PubMed ID: 25241797
    [Abstract] [Full Text] [Related]

  • 13. Dioscin-6'-O-acetate inhibits lung cancer cell proliferation via inducing cell cycle arrest and caspase-dependent apoptosis.
    Li X, Qu Z, Jing S, Li X, Zhao C, Man S, Wang Y, Gao W.
    Phytomedicine; 2019 Feb 15; 53():124-133. PubMed ID: 30668391
    [Abstract] [Full Text] [Related]

  • 14. Total saponins from Tupistra chinensis baker inhibits growth of human gastric cancer cells in vitro and in vivo.
    Wang Z, Xu J, Wang Y, Xiang L, He X.
    J Ethnopharmacol; 2021 Oct 05; 278():114323. PubMed ID: 34116191
    [Abstract] [Full Text] [Related]

  • 15. Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer.
    Teng JF, Qin DL, Mei QB, Qiu WQ, Pan R, Xiong R, Zhao Y, Law BY, Wong VK, Tang Y, Yu CL, Zhang F, Wu JM, Wu AG.
    Pharmacol Res; 2019 Sep 05; 147():104396. PubMed ID: 31404628
    [Abstract] [Full Text] [Related]

  • 16. New 23, 27-dihydroxy-oleanane-type triterpenoid saponins from Anemone Raddeana Regel.
    Lv C, Zhao Y, Zhao B, Han L, Lu J.
    Nat Prod Res; 2021 Feb 05; 35(3):384-391. PubMed ID: 31264473
    [Abstract] [Full Text] [Related]

  • 17. Total saponins of Bolbostemma paniculatum (maxim.) Franquet exert antitumor activity against MDA-MB-231 human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway.
    Dou JW, Shang RG, Lei XQ, Li KL, Guo ZZ, Ye K, Yang XJ, Li YW, Zhou YY, Yao J, Huang Q.
    BMC Complement Altern Med; 2019 Nov 08; 19(1):304. PubMed ID: 31703679
    [Abstract] [Full Text] [Related]

  • 18. Chloroform extract from Sophora Tonkinensis Gagnep. inhibit proliferation, migration, invasion and promote apoptosis of nasopharyngeal carcinoma cells by silencing the PI3K/AKT/mTOR signaling pathway.
    ShuoWang, Song Z, Gong X, Ou C, Zhang W, Wang J, Yao C, Qin S, Yan B, Li Q, Wei K, Hou X, Zhou X, Miao J.
    J Ethnopharmacol; 2021 May 10; 271():113879. PubMed ID: 33524509
    [Abstract] [Full Text] [Related]

  • 19. Paris saponin-induced autophagy promotes breast cancer cell apoptosis via the Akt/mTOR signaling pathway.
    Xie ZZ, Li MM, Deng PF, Wang S, Wang L, Lu XP, Hu LB, Chen Z, Jie HY, Wang YF, Liu XX, Liu Z.
    Chem Biol Interact; 2017 Feb 25; 264():1-9. PubMed ID: 28088315
    [Abstract] [Full Text] [Related]

  • 20. Amorphophalli Rhizoma inhibits breast cancer growth, proliferation, migration, and invasion via the PI3K/AKT pathway.
    Li H, Chen M, Yang Z, Xu C, Yu Q, Song J, Wang M, Gao X.
    J Ethnopharmacol; 2022 Mar 25; 286():114926. PubMed ID: 34929308
    [Abstract] [Full Text] [Related]


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