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232 related items for PubMed ID: 32476407

  • 1. Oral Dosing of Dihydromethysticin Ahead of Tobacco Carcinogen NNK Effectively Prevents Lung Tumorigenesis in A/J Mice.
    Hu Q, Corral P, Narayanapillai SC, Leitzman P, Upadhyaya P, O'Sullivan MG, Hecht SS, Lu J, Xing C.
    Chem Res Toxicol; 2020 Jul 20; 33(7):1980-1988. PubMed ID: 32476407
    [Abstract] [Full Text] [Related]

  • 2. Dihydromethysticin from kava blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis and differentially reduces DNA damage in A/J mice.
    Narayanapillai SC, Balbo S, Leitzman P, Grill AE, Upadhyaya P, Shaik AA, Zhou B, O'Sullivan MG, Peterson LA, Lu J, Hecht SS, Xing C.
    Carcinogenesis; 2014 Oct 20; 35(10):2365-72. PubMed ID: 25053626
    [Abstract] [Full Text] [Related]

  • 3. Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification.
    Narayanapillai SC, von Weymarn LB, Carmella SG, Leitzman P, Paladino J, Upadhyaya P, Hecht SS, Murphy SE, Xing C.
    Drug Metab Dispos; 2016 Mar 20; 44(3):422-7. PubMed ID: 26744252
    [Abstract] [Full Text] [Related]

  • 4. Dihydromethysticin (DHM) Blocks Tobacco Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-Induced O6-Methylguanine in a Manner Independent of the Aryl Hydrocarbon Receptor (AhR) Pathway in C57BL/6 Female Mice.
    Narayanapillai SC, Lin SH, Leitzman P, Upadhyaya P, Baglole CJ, Xing C.
    Chem Res Toxicol; 2016 Nov 21; 29(11):1828-1834. PubMed ID: 27728767
    [Abstract] [Full Text] [Related]

  • 5. Effects of dietary 1,4-phenylenebis(methylene)selenocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation in lung and liver of A/J mice and F344 rats.
    Prokopczyk B, Cox JE, Upadhyaya P, Amin S, Desai D, Hoffmann D, el-Bayoumy K.
    Carcinogenesis; 1996 Apr 21; 17(4):749-53. PubMed ID: 8625486
    [Abstract] [Full Text] [Related]

  • 6. Suppressing the activation of protein kinase A as a DNA damage-independent mechanistic lead for dihydromethysticin prophylaxis of NNK-induced lung carcinogenesis.
    Bian T, Ding H, Wang Y, Hu Q, Chen S, Fujioka N, Aly FZ, Lu J, Huo Z, Xing C.
    Carcinogenesis; 2022 Aug 30; 43(7):659-670. PubMed ID: 35353881
    [Abstract] [Full Text] [Related]

  • 7. Kava blocks 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in association with reducing O6-methylguanine DNA adduct in A/J mice.
    Leitzman P, Narayanapillai SC, Balbo S, Zhou B, Upadhyaya P, Shaik AA, O'Sullivan MG, Hecht SS, Lu J, Xing C.
    Cancer Prev Res (Phila); 2014 Jan 30; 7(1):86-96. PubMed ID: 24403291
    [Abstract] [Full Text] [Related]

  • 8. The effect of a 2-h exposure to cigarette smoke on the metabolic activation of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mice.
    Brown BG, Richter E, Tricker AR, Ayres PH, Doolittle DJ.
    Chem Biol Interact; 2001 Nov 28; 138(2):125-35. PubMed ID: 11672696
    [Abstract] [Full Text] [Related]

  • 9. Lung tumor induction in A/J mice by the tobacco smoke carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene: a potentially useful model for evaluation of chemopreventive agents.
    Hecht SS, Isaacs S, Trushin N.
    Carcinogenesis; 1994 Dec 28; 15(12):2721-5. PubMed ID: 8001227
    [Abstract] [Full Text] [Related]

  • 10. Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers and metabolites in the A/J mouse.
    Upadhyaya P, Kenney PM, Hochalter JB, Wang M, Hecht SS.
    Carcinogenesis; 1999 Aug 28; 20(8):1577-82. PubMed ID: 10426810
    [Abstract] [Full Text] [Related]

  • 11. Effects of phenethyl isothiocyanate and benzyl isothiocyanate, individually and in combination, on lung tumorigenesis induced in A/J mice by benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Hecht SS, Kenney PM, Wang M, Trushin N, Upadhyaya P.
    Cancer Lett; 2000 Mar 13; 150(1):49-56. PubMed ID: 10755386
    [Abstract] [Full Text] [Related]

  • 12. Pilot in Vivo Structure-Activity Relationship of Dihydromethysticin in Blocking 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced O6-Methylguanine and Lung Tumor in A/J Mice.
    Puppala M, Narayanapillai SC, Leitzman P, Sun H, Upadhyaya P, O'Sullivan MG, Hecht SS, Xing C.
    J Med Chem; 2017 Sep 28; 60(18):7935-7940. PubMed ID: 28806079
    [Abstract] [Full Text] [Related]

  • 13. Inhibitory effects of 6-phenylhexyl isothiocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolic activation and lung tumorigenesis in rats.
    Hecht SS, Trushin N, Rigotty J, Carmella SG, Borukhova A, Akerkar S, Desai D, Amin S, Rivenson A.
    Carcinogenesis; 1996 Sep 28; 17(9):2061-7. PubMed ID: 8824535
    [Abstract] [Full Text] [Related]

  • 14. Elevated 8-hydroxy-2'-deoxyguanosine levels in lung DNA of A/J mice and F344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and inhibition by dietary 1,4-phenylenebis(methylene)selenocyanate.
    Rosa JG, Prokopczyk B, Desai DH, Amin SG, El-Bayoumy K.
    Carcinogenesis; 1998 Oct 28; 19(10):1783-8. PubMed ID: 9806159
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of lung tumourigenesis by sulindac: comparison of two experimental protocols.
    Castonguay A, Rioux N.
    Carcinogenesis; 1997 Mar 28; 18(3):491-6. PubMed ID: 9067547
    [Abstract] [Full Text] [Related]

  • 16. Chemoprevention of lung tumorigenesis induced by a mixture of benzo(a)pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by the organoselenium compound 1,4-phenylenebis(methylene)selenocyanate.
    Prokopczyk B, Rosa JG, Desai D, Amin S, Sohn OS, Fiala ES, El-Bayoumy K.
    Cancer Lett; 2000 Dec 08; 161(1):35-46. PubMed ID: 11078911
    [Abstract] [Full Text] [Related]

  • 17. Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice.
    Morse MA, LaGreca SD, Amin SG, Chung FL.
    Cancer Res; 1990 May 01; 50(9):2613-7. PubMed ID: 2328487
    [Abstract] [Full Text] [Related]

  • 18. Complete inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced rat lung tumorigenesis and favorable modification of biomarkers by phenethyl isothiocyanate.
    Hecht SS, Trushin N, Rigotty J, Carmella SG, Borukhova A, Akerkar S, Rivenson A.
    Cancer Epidemiol Biomarkers Prev; 1996 Aug 01; 5(8):645-52. PubMed ID: 8824368
    [Abstract] [Full Text] [Related]

  • 19. Analysis of human urine for pyridine-N-oxide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific lung carcinogen.
    Carmella SG, Borukhova A, Akerkar SA, Hecht SS.
    Cancer Epidemiol Biomarkers Prev; 1997 Feb 01; 6(2):113-20. PubMed ID: 9037562
    [Abstract] [Full Text] [Related]

  • 20. Chemopreventive effects and anti-tumorigenic mechanisms of 2,6-dimethoxy-1,4-benzoquinone, a constituent of Vitis coignetiae Pulliat (crimson glory vine, known as yamabudo in Japan), toward 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice.
    Arimoto-Kobayashi S, Sasaki K, Hida R, Miyake N, Fujii N, Saiki Y, Daimaru K, Nakashima H, Kubo T, Kiura K.
    Food Chem Toxicol; 2021 Aug 01; 154():112319. PubMed ID: 34087405
    [Abstract] [Full Text] [Related]

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