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Journal Abstract Search

169 related items for PubMed ID: 32500832

  • 1. Effects of glutathione and cysteine on pyrrolizidine alkaloid-induced hepatotoxicity and DNA adduct formation in rat primary hepatocytes.
    He X, Xia Q, Shi Q, Fu PP.
    J Environ Sci Health C Toxicol Carcinog; 2020; 38(2):109-123. PubMed ID: 32500832
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  • 5. Primary and secondary pyrrolic metabolites of pyrrolizidine alkaloids form DNA adducts in human A549 cells.
    He X, Xia Q, Wu Q, Tolleson WH, Lin G, Fu PP.
    Toxicol In Vitro; 2019 Feb; 54():286-294. PubMed ID: 30366057
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  • 6. 9-Glutathionyl-6,7-dihydro-1-hydroxymethyl-5H-pyrrolizine Is the Major Pyrrolic Glutathione Conjugate of Retronecine-Type Pyrrolizidine Alkaloids in Liver Microsomes and in Rats.
    Chen M, Li L, Zhong D, Shen S, Zheng J, Chen X.
    Chem Res Toxicol; 2016 Feb 15; 29(2):180-9. PubMed ID: 26761523
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  • 7. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.
    Wang YP, Yan J, Fu PP, Chou MW.
    Toxicol Lett; 2005 Mar 15; 155(3):411-20. PubMed ID: 15649625
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  • 8. 1-Formyl-7-hydroxy-6,7-dihydro-5 H-pyrrolizine (1-CHO-DHP): A Potential Proximate Carcinogenic Metabolite of Pyrrolizidine Alkaloids.
    He X, Xia Q, Gamboa da Costa G, Lin G, Fu PP.
    Chem Res Toxicol; 2019 Jun 17; 32(6):1193-1203. PubMed ID: 31120748
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  • 9. Quantitation of DNA reactive pyrrolic metabolites of senecionine - A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis.
    Xia Q, He X, Shi Q, Lin G, Fu PP.
    J Food Drug Anal; 2020 Jan 17; 28(1):167-174. PubMed ID: 31883605
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  • 11. Metabolic formation of DHP-derived DNA adducts from a representative otonecine type pyrrolizidine alkaloid clivorine and the extract of Ligularia hodgsonnii hook.
    Xia Q, Chou MW, Lin G, Fu PP.
    Chem Res Toxicol; 2004 May 17; 17(5):702-8. PubMed ID: 15144228
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  • 12. 7-N-Acetylcysteine-pyrrole conjugate-A potent DNA reactive metabolite of pyrrolizidine alkaloids.
    He X, Ma L, Xia Q, Fu PP.
    J Food Drug Anal; 2016 Oct 17; 24(4):682-694. PubMed ID: 28911605
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  • 13. Metabolic activation of the tumorigenic pyrrolizidine alkaloid, retrorsine, leading to DNA adduct formation in vivo.
    Wang YP, Fu PP, Chou MW.
    Int J Environ Res Public Health; 2005 Apr 17; 2(1):74-9. PubMed ID: 16705803
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  • 14. Metabolic activation of the tumorigenic pyrrolizidine alkaloid, monocrotaline, leading to DNA adduct formation in vivo.
    Wang YP, Yan J, Beger RD, Fu PP, Chou MW.
    Cancer Lett; 2005 Aug 08; 226(1):27-35. PubMed ID: 16004930
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  • 15. Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine.
    Chou MW, Wang YP, Yan J, Yang YC, Beger RD, Williams LD, Doerge DR, Fu PP.
    Toxicol Lett; 2003 Dec 10; 145(3):239-47. PubMed ID: 14580895
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  • 16. 7-glutathione pyrrole adduct: a potential DNA reactive metabolite of pyrrolizidine alkaloids.
    Xia Q, Ma L, He X, Cai L, Fu PP.
    Chem Res Toxicol; 2015 Apr 20; 28(4):615-20. PubMed ID: 25768656
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  • 17. Identification of DNA adducts derived from riddelliine, a carcinogenic pyrrolizidine alkaloid.
    Chou MW, Jian Y, Williams LD, Xia Q, Churchwell M, Doerge DR, Fu PP.
    Chem Res Toxicol; 2003 Sep 20; 16(9):1130-7. PubMed ID: 12971801
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  • 19. Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, lasiocarpine.
    Xia Q, Chou MW, Edgar JA, Doerge DR, Fu PP.
    Cancer Lett; 2006 Jan 08; 231(1):138-45. PubMed ID: 16356839
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  • 20. Metabolic activation of retronecine and retronecine N-oxide - formation of DHP-derived DNA adducts.
    Yan J, Xia Q, Chou MW, Fu PP.
    Toxicol Ind Health; 2008 Apr 08; 24(3):181-8. PubMed ID: 18842697
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