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Journal Abstract Search

461 related items for PubMed ID: 32527460

  • 1. Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.
    El-Shafey HW, Gomaa RM, El-Messery SM, Goda FE.
    Bioorg Med Chem Lett; 2020 Aug 01; 30(15):127281. PubMed ID: 32527460
    [Abstract] [Full Text] [Related]

  • 2. Synthetic approaches, anticancer potential, HSP90 inhibition, multitarget evaluation, molecular modeling and apoptosis mechanistic study of thioquinazolinone skeleton: Promising antibreast cancer agent.
    El-Shafey HW, Gomaa RM, El-Messery SM, Goda FE.
    Bioorg Chem; 2020 Aug 01; 101():103987. PubMed ID: 32540783
    [Abstract] [Full Text] [Related]

  • 3. Identification of New Hsp90 Inhibitors: Structure Based Virtual Screening, Molecular Dynamic Simulation, Synthesis and Biological Evaluation.
    Abbasi M, Amanlou M, Aghaei M, Hassanzadeh F, Sadeghi-Aliabadi H.
    Anticancer Agents Med Chem; 2021 Aug 01; 21(18):2583-2591. PubMed ID: 33563187
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis and biological evaluation of 7-(aryl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinoline derivatives as potential Hsp90 inhibitors and anticancer agents.
    Malayeri SO, Abnous K, Arab A, Akaberi M, Mehri S, Zarghi A, Ghodsi R.
    Bioorg Med Chem; 2017 Feb 01; 25(3):1294-1302. PubMed ID: 28073608
    [Abstract] [Full Text] [Related]

  • 5. Discovery of 5-aryl-3-thiophen-2-yl-1H-pyrazoles as a new class of Hsp90 inhibitors in hepatocellular carcinoma.
    Mohamady S, Ismail MI, Mogheith SM, Attia YM, Taylor SD.
    Bioorg Chem; 2020 Jan 01; 94():103433. PubMed ID: 31785857
    [Abstract] [Full Text] [Related]

  • 6. Design, green synthesis, molecular docking and anticancer evaluations of diazepam bearing sulfonamide moieties as VEGFR-2 inhibitors.
    Saleh NM, El-Gaby MSA, El-Adl K, Abd El-Sattar NEA.
    Bioorg Chem; 2020 Nov 01; 104():104350. PubMed ID: 33142416
    [Abstract] [Full Text] [Related]

  • 7. Novel O-acylated (E)-3-aryl-6,7-dihydrobenzisoxazol-4(5H)-one oximes targeting HSP90-HER2 axis in breast cancer cells.
    Piven YA, Yastrebova MA, Khamidullina AI, Scherbakov AM, Tatarskiy VV, Rusanova JA, Baranovsky AV, Zinovich VG, Khlebnicova TS, Lakhvich FA.
    Bioorg Med Chem; 2022 Jan 01; 53():116521. PubMed ID: 34844036
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and molecular docking studies of thymol based 1,2,3-triazole hybrids as thymidylate synthase inhibitors and apoptosis inducers against breast cancer cells.
    Alam MM, Malebari AM, Syed N, Neamatallah T, Almalki ASA, Elhenawy AA, Obaid RJ, Alsharif MA.
    Bioorg Med Chem; 2021 May 15; 38():116136. PubMed ID: 33894490
    [Abstract] [Full Text] [Related]

  • 9. Discovery of indazole inhibitors for heat shock protein 90 as anti-cancer agents.
    La MT, Hoang VH, Sahu R, Nguyen CT, Nam G, Park HJ, Park M, Kim YJ, Kim JY, Ann J, Seo JH, Lee J.
    Eur J Med Chem; 2024 Oct 05; 276():116620. PubMed ID: 38971048
    [Abstract] [Full Text] [Related]

  • 10. Pyridazino[1,6-b]quinazolinones as new anticancer scaffold: Synthesis, DNA intercalation, topoisomerase I inhibition and antitumor evaluation in vitro and in vivo.
    Huang WY, Zhang XR, Lyu L, Wang SQ, Zhang XT.
    Bioorg Chem; 2020 Jun 05; 99():103814. PubMed ID: 32278208
    [Abstract] [Full Text] [Related]

  • 11. Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents.
    Kim HS, Hoang VH, Hong M, Chul Kim K, Ann J, Nguyen CT, Seo JH, Choi H, Yong Kim J, Kim KW, Sub Byun W, Lee S, Lee S, Suh YG, Chen J, Park HJ, Cho TM, Kim JY, Seo JH, Lee J.
    Bioorg Med Chem; 2019 Apr 01; 27(7):1370-1381. PubMed ID: 30827868
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity.
    ElZahabi HSA, Nafie MS, Osman D, Elghazawy NH, Soliman DH, El-Helby AAH, Arafa RK.
    Eur J Med Chem; 2021 Oct 15; 222():113609. PubMed ID: 34119830
    [Abstract] [Full Text] [Related]

  • 13. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE, Gedawy EM.
    Eur J Med Chem; 2018 Apr 25; 150():403-418. PubMed ID: 29547830
    [Abstract] [Full Text] [Related]

  • 14. Design and molecular modeling of novel P38α MAPK inhibitors targeting breast cancer, synthesized from oxygen heterocyclic natural compounds.
    Abdelhafez OM, Ahmed EY, Abdel Latif NA, Arafa RK, Abd Elmageed ZY, Ali HI.
    Bioorg Med Chem; 2019 Apr 01; 27(7):1308-1319. PubMed ID: 30792101
    [Abstract] [Full Text] [Related]

  • 15. VEGFR-2 inhibiting effect and molecular modeling of newly synthesized coumarin derivatives as anti-breast cancer agents.
    Ahmed EY, Abdel Latif NA, El-Mansy MF, Elserwy WS, Abdelhafez OM.
    Bioorg Med Chem; 2020 Mar 01; 28(5):115328. PubMed ID: 31992477
    [Abstract] [Full Text] [Related]

  • 16. Discovery of a simplified deguelin analog as an HSP90 C-terminal inhibitor for HER2-positive breast cancer.
    Nguyen CT, Thanh La M, Ann J, Nam G, Park HJ, Min Park J, Kim YJ, Young Kim J, Hong Seo J, Lee J.
    Bioorg Med Chem Lett; 2021 Aug 01; 45():128134. PubMed ID: 34044120
    [Abstract] [Full Text] [Related]

  • 17. Biological Activity, Apoptotic Induction and Cell Cycle Arrest of New Hydrazonoyl Halides Derivatives.
    Mohamed MF, Hassaneen HM, Elzayat EM, El-Hallouty SM, El-Manawaty M, Saleh FM, Mohamed Y, El-Zohiry D, Fahmy G, Abdelaal N, Hassanin N, Hossam N.
    Anticancer Agents Med Chem; 2019 Aug 01; 19(9):1141-1149. PubMed ID: 30843494
    [Abstract] [Full Text] [Related]

  • 18. Antitumor activity, multitarget mechanisms, and molecular docking studies of quinazoline derivatives based on a benzenesulfonamide scaffold: Cell cycle analysis.
    El-Azab AS, Abdel-Aziz AA, AlSaif NA, Alkahtani HM, Alanazi MM, Obaidullah AJ, Eskandrani RO, Alharbi A.
    Bioorg Chem; 2020 Nov 01; 104():104345. PubMed ID: 33142413
    [Abstract] [Full Text] [Related]

  • 19. Quinazolin-4(3H)-one based potential multiple tyrosine kinase inhibitors with excellent cytotoxicity.
    Mirgany TO, Abdalla AN, Arifuzzaman M, Motiur Rahman AFM, Al-Salem HS.
    J Enzyme Inhib Med Chem; 2021 Dec 01; 36(1):2055-2067. PubMed ID: 34551654
    [Abstract] [Full Text] [Related]

  • 20. Design and synthesis of thienopyrimidine urea derivatives with potential cytotoxic and pro-apoptotic activity against breast cancer cell line MCF-7.
    Abdelhaleem EF, Abdelhameid MK, Kassab AE, Kandeel MM.
    Eur J Med Chem; 2018 Jan 01; 143():1807-1825. PubMed ID: 29133058
    [Abstract] [Full Text] [Related]

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