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159 related items for PubMed ID: 32527535

  • 1. Synthesis, in vitro ADME profiling and in vivo pharmacological evaluation of novel glycogen phosphorylase inhibitors.
    Miao GX, Wang YD, Yan ZW, Zhang LY.
    Bioorg Med Chem Lett; 2020 Jul 15; 30(14):127117. PubMed ID: 32527535
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors.
    Onda K, Shiraki R, Ogiyama T, Yokoyama K, Momose K, Katayama N, Orita M, Yamaguchi T, Furutani M, Hamada N, Takeuchi M, Okada M, Ohta M, Tsukamoto S.
    Bioorg Med Chem; 2008 Dec 01; 16(23):10001-12. PubMed ID: 18952447
    [Abstract] [Full Text] [Related]

  • 3. Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition.
    Goyard D, Kónya B, Chajistamatiou AS, Chrysina ED, Leroy J, Balzarin S, Tournier M, Tousch D, Petit P, Duret C, Maurel P, Somsák L, Docsa T, Gergely P, Praly JP, Azay-Milhau J, Vidal S.
    Eur J Med Chem; 2016 Jan 27; 108():444-454. PubMed ID: 26708111
    [Abstract] [Full Text] [Related]

  • 4. Discovery and evaluation of novel benzazepinone derivatives as glycogen phosphorylase inhibitors with potent activity.
    Wang Y, Yan Z, Guo Y, Zhang L.
    Future Med Chem; 2021 May 27; 13(10):897-909. PubMed ID: 33906369
    [Abstract] [Full Text] [Related]

  • 5. Synthesis of 5-chloro-N-aryl-1H-indole-2-carboxamide derivatives as inhibitors of human liver glycogen phosphorylase a.
    Onda K, Suzuki T, Shiraki R, Yonetoku Y, Negoro K, Momose K, Katayama N, Orita M, Yamaguchi T, Ohta M, Tsukamoto S.
    Bioorg Med Chem; 2008 May 15; 16(10):5452-64. PubMed ID: 18434170
    [Abstract] [Full Text] [Related]

  • 6. Indole-2-carboxamide inhibitors of human liver glycogen phosphorylase.
    Hoover DJ, Lefkowitz-Snow S, Burgess-Henry JL, Martin WH, Armento SJ, Stock IA, McPherson RK, Genereux PE, Gibbs EM, Treadway JL.
    J Med Chem; 1998 Jul 30; 41(16):2934-8. PubMed ID: 9685232
    [No Abstract] [Full Text] [Related]

  • 7. Exploring the Dual Inhibitory Activity of Novel Anthranilic Acid Derivatives towards α-Glucosidase and Glycogen Phosphorylase Antidiabetic Targets: Design, In Vitro Enzyme Assay, and Docking Studies.
    Ihmaid S.
    Molecules; 2018 May 29; 23(6):. PubMed ID: 29844263
    [Abstract] [Full Text] [Related]

  • 8. Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase.
    Harwood HJ, Petras SF, Hoover DJ, Mankowski DC, Soliman VF, Sugarman ED, Hulin B, Kwon Y, Gibbs EM, Mayne JT, Treadway JL.
    J Lipid Res; 2005 Mar 29; 46(3):547-63. PubMed ID: 15604516
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological evaluation of asiatic acid derivatives as inhibitors of glycogen phosphorylases.
    Zhang L, Chen J, Gong Y, Liu J, Zhang L, Hua W, Sun H.
    Chem Biodivers; 2009 Jun 29; 6(6):864-74. PubMed ID: 19551727
    [Abstract] [Full Text] [Related]

  • 10. Glucose-lowering in a db/db mouse model by dihydropyridine diacid glycogen phosphorylase inhibitors.
    Ogawa AK, Willoughby CA, Bergeron R, Ellsworth KP, Geissler WM, Myers RW, Yao J, Harris G, Chapman KT.
    Bioorg Med Chem Lett; 2003 Oct 20; 13(20):3405-8. PubMed ID: 14505637
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors.
    Dudash J, Zhang Y, Moore JB, Look R, Liang Y, Beavers MP, Conway BR, Rybczynski PJ, Demarest KT.
    Bioorg Med Chem Lett; 2005 Nov 01; 15(21):4790-3. PubMed ID: 16143521
    [Abstract] [Full Text] [Related]

  • 12. Glucose-based spiro-oxathiazoles as in vivo anti-hyperglycemic agents through glycogen phosphorylase inhibition.
    Goyard D, Kónya B, Czifrák K, Larini P, Demontrond F, Leroy J, Balzarin S, Tournier M, Tousch D, Petit P, Duret C, Maurel P, Docsa T, Gergely P, Somsák L, Praly JP, Azay-Milhau J, Vidal S.
    Org Biomol Chem; 2020 Feb 07; 18(5):931-940. PubMed ID: 31922157
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and evaluation of novel oleanolic acid derivatives as potential antidiabetic agents.
    Zhang L, Jia X, Dong J, Chen D, Liu J, Zhang L, Wen X.
    Chem Biol Drug Des; 2014 Mar 07; 83(3):297-305. PubMed ID: 24119242
    [Abstract] [Full Text] [Related]

  • 14. Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase.
    Chen J, Liu J, Zhang L, Wu G, Hua W, Wu X, Sun H.
    Bioorg Med Chem Lett; 2006 Jun 01; 16(11):2915-9. PubMed ID: 16546381
    [Abstract] [Full Text] [Related]

  • 15. The effect of glucose on the potency of two distinct glycogen phosphorylase inhibitors.
    Andersen B, Westergaard N.
    Biochem J; 2002 Oct 15; 367(Pt 2):443-50. PubMed ID: 12099891
    [Abstract] [Full Text] [Related]

  • 16. Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site.
    Kristiansen M, Andersen B, Iversen LF, Westergaard N.
    J Med Chem; 2004 Jul 01; 47(14):3537-45. PubMed ID: 15214781
    [Abstract] [Full Text] [Related]

  • 17. 2-Oxo-1,2-dihydropyridinyl-3-yl amide-based GPa inhibitors: Design, synthesis and structure-activity relationship study.
    Loughlin WA, Jenkins ID, Karis ND, Schweiker SS, Healy PC.
    Eur J Med Chem; 2016 Mar 23; 111():1-14. PubMed ID: 26851835
    [Abstract] [Full Text] [Related]

  • 18. Synthesis of (benzimidazol-2-yl)aniline derivatives as glycogen phosphorylase inhibitors.
    Galal SA, Khattab M, Andreadaki F, Chrysina ED, Praly JP, Ragab FAF, El Diwani HI.
    Bioorg Med Chem; 2016 Nov 01; 24(21):5423-5430. PubMed ID: 27624527
    [Abstract] [Full Text] [Related]

  • 19. Novel Liver-targeted conjugates of Glycogen Phosphorylase Inhibitor PSN-357 for the Treatment of Diabetes: Design, Synthesis, Pharmacokinetic and Pharmacological Evaluations.
    Zhang L, Song C, Miao G, Zhao L, Yan Z, Li J, Wang Y.
    Sci Rep; 2017 Feb 22; 7():42251. PubMed ID: 28225016
    [Abstract] [Full Text] [Related]

  • 20. Glycogen phosphorylase inhibitors: a patent review (2013 - 2015).
    Donnier-Maréchal M, Vidal S.
    Expert Opin Ther Pat; 2016 Feb 22; 26(2):199-212. PubMed ID: 26666989
    [Abstract] [Full Text] [Related]

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