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Journal Abstract Search

159 related items for PubMed ID: 32527535

  • 21. Synthesis, screening and docking of small heterocycles as glycogen phosphorylase inhibitors.
    Schweiker SS, Loughlin WA, Lohning AS, Petersson MJ, Jenkins ID.
    Eur J Med Chem; 2014 Sep 12; 84():584-94. PubMed ID: 25062009
    [Abstract] [Full Text] [Related]

  • 22. Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy.
    Thomson SA, Banker P, Bickett DM, Boucheron JA, Carter HL, Clancy DC, Cooper JP, Dickerson SH, Garrido DM, Nolte RT, Peat AJ, Sheckler LR, Sparks SM, Tavares FX, Wang L, Wang TY, Weiel JE.
    Bioorg Med Chem Lett; 2009 Feb 15; 19(4):1177-82. PubMed ID: 19138846
    [Abstract] [Full Text] [Related]

  • 23. Pharmacokinetics and anti-hyperglycaemic efficacy of a novel inhibitor of glycogen phosphorylase, 1,4-dideoxy-1,4-imino-d- arabinitol, in glucagon-challenged rats and dogs and in diabetic ob/ob mice.
    Mackay P, Ynddal L, Andersen JV, McCormack JG.
    Diabetes Obes Metab; 2003 Nov 15; 5(6):397-407. PubMed ID: 14617225
    [Abstract] [Full Text] [Related]

  • 24. Physiological control of liver glycogen metabolism: lessons from novel glycogen phosphorylase inhibitors.
    Agius L.
    Mini Rev Med Chem; 2010 Oct 15; 10(12):1175-87. PubMed ID: 20716056
    [Abstract] [Full Text] [Related]

  • 25. Novel 5-(1-aryl-1H-pyrazol-3-yl)-1H-tetrazoles as glycogen phosphorylase inhibitors: An in vivo antihyperglycemic activity study.
    Kattimani PP, Somagond SM, Bayannavar PK, Kamble RR, Bijjaragi SC, Hunnur RK, Joshi SD.
    Drug Dev Res; 2020 Feb 15; 81(1):70-84. PubMed ID: 31696542
    [Abstract] [Full Text] [Related]

  • 26. Advances in glycogen phosphorylase inhibitor design.
    Oikonomakos NG, Somsák L.
    Curr Opin Investig Drugs; 2008 Apr 15; 9(4):379-95. PubMed ID: 18393105
    [Abstract] [Full Text] [Related]

  • 27. 5-Chloroindoloyl glycine amide inhibitors of glycogen phosphorylase: synthesis, in vitro, in vivo, and X-ray crystallographic characterization.
    Wright SW, Rath VL, Genereux PE, Hageman DL, Levy CB, McClure LD, McCoid SC, McPherson RK, Schelhorn TM, Wilder DE, Zavadoski WJ, Gibbs EM, Treadway JL.
    Bioorg Med Chem Lett; 2005 Jan 17; 15(2):459-65. PubMed ID: 15603973
    [Abstract] [Full Text] [Related]

  • 28. Combined in silico and in vitro studies to identify novel antidiabetic flavonoids targeting glycogen phosphorylase.
    Brás NF, Neves RPP, Lopes FAA, Correia MAS, Palma AS, Sousa SF, Ramos MJ.
    Bioorg Chem; 2021 Mar 17; 108():104552. PubMed ID: 33357981
    [Abstract] [Full Text] [Related]

  • 29. Development of potent, orally active 1-substituted-3,4-dihydro-2-quinolone glycogen phosphorylase inhibitors.
    Birch AM, Kenny PW, Oikonomakos NG, Otterbein L, Schofield P, Whittamore PR, Whalley DP.
    Bioorg Med Chem Lett; 2007 Jan 15; 17(2):394-9. PubMed ID: 17095214
    [Abstract] [Full Text] [Related]

  • 30. Terpenoids. III: Synthesis and biological evaluation of 23-hydroxybetulinic acid derivatives as novel inhibitors of glycogen phosphorylase.
    Zhu P, Bi Y, Xu J, Li Z, Liu J, Zhang L, Ye W, Wu X.
    Bioorg Med Chem Lett; 2009 Dec 15; 19(24):6966-9. PubMed ID: 19889536
    [Abstract] [Full Text] [Related]

  • 31. Design, synthesis and biological evaluation of some tetrazole acetamide derivatives as novel non-carboxylic PTP1B inhibitors.
    Maheshwari N, Karthikeyan C, Bhadada SV, Verma AK, Sahi C, Moorthy NSHN, Trivedi P.
    Bioorg Chem; 2019 Nov 15; 92():103221. PubMed ID: 31499261
    [Abstract] [Full Text] [Related]

  • 32. Synthesis of N-glucopyranosidic derivatives as potential inhibitors that bind at the catalytic site of glycogen phosphorylase.
    Gimisis T.
    Mini Rev Med Chem; 2010 Oct 15; 10(12):1127-38. PubMed ID: 20716054
    [Abstract] [Full Text] [Related]

  • 33. A multidisciplinary study of 3-(β-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors.
    Kun S, Begum J, Kyriakis E, Stamati ECV, Barkas TA, Szennyes E, Bokor É, Szabó KE, Stravodimos GA, Sipos Á, Docsa T, Gergely P, Moffatt C, Patraskaki MS, Kokolaki MC, Gkerdi A, Skamnaki VT, Leonidas DD, Somsák L, Hayes JM.
    Eur J Med Chem; 2018 Mar 10; 147():266-278. PubMed ID: 29453094
    [Abstract] [Full Text] [Related]

  • 34. Recent advances in the allosteric inhibition of glycogen phosphorylase.
    Loughlin WA.
    Mini Rev Med Chem; 2010 Oct 10; 10(12):1139-55. PubMed ID: 20716052
    [Abstract] [Full Text] [Related]

  • 35. An assessment of the in vivo efficacy of the glycogen phosphorylase inhibitor GPi688 in rat models of hyperglycaemia.
    Poucher SM, Freeman S, Loxham SJ, Convey G, Bartlett JB, De Schoolmeester J, Teague J, Walker M, Turnbull AV, Charles AD, Carey F, Berg S.
    Br J Pharmacol; 2007 Dec 10; 152(8):1239-47. PubMed ID: 17934512
    [Abstract] [Full Text] [Related]

  • 36. Pentacyclic triterpenes. Part 1: the first examples of naturally occurring pentacyclic triterpenes as a new class of inhibitors of glycogen phosphorylases.
    Wen X, Sun H, Liu J, Wu G, Zhang L, Wu X, Ni P.
    Bioorg Med Chem Lett; 2005 Nov 15; 15(22):4944-8. PubMed ID: 16169219
    [Abstract] [Full Text] [Related]

  • 37. Identification of C-β-d-Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: In Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies.
    Barr D, Szennyes E, Bokor É, Al-Oanzi ZH, Moffatt C, Kun S, Docsa T, Sipos Á, Davies MP, Mathomes RT, Snape TJ, Agius L, Somsák L, Hayes JM.
    ACS Chem Biol; 2019 Jul 19; 14(7):1460-1470. PubMed ID: 31243960
    [Abstract] [Full Text] [Related]

  • 38. Synthesis and glycogen phosphorylase inhibitor activity of functionalized 1,4-benzodioxanes.
    Czakó Z, Docsa T, Gergely P, Juhász L, Antus S.
    Pharmazie; 2010 Apr 19; 65(4):235-8. PubMed ID: 20432616
    [Abstract] [Full Text] [Related]

  • 39. Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.
    Chen L, Li H, Liu J, Zhang L, Liu H, Jiang H.
    Bioorg Med Chem; 2007 Nov 01; 15(21):6763-74. PubMed ID: 17719791
    [Abstract] [Full Text] [Related]

  • 40. Glycogen phosphorylase inhibitor N-(3,5-dimethyl-Benzoyl)-N'-(β-D-glucopyranosyl)urea improves glucose tolerance under normoglycemic and diabetic conditions and rearranges hepatic metabolism.
    Nagy L, Docsa T, Szántó M, Brunyánszki A, Hegedűs C, Márton J, Kónya B, Virág L, Somsák L, Gergely P, Bai P.
    PLoS One; 2013 Nov 01; 8(7):e69420. PubMed ID: 23936011
    [Abstract] [Full Text] [Related]

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