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Journal Abstract Search

225 related items for PubMed ID: 32533369

  • 1. Predicting reactivity to drug metabolism: beyond P450s-modelling FMOs and UGTs.
    Öeren M, Walton PJ, Hunt PA, Ponting DJ, Segall MD.
    J Comput Aided Mol Des; 2021 Apr; 35(4):541-555. PubMed ID: 32533369
    [Abstract] [Full Text] [Related]

  • 2. Renal drug metabolism in humans: the potential for drug-endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT).
    Knights KM, Rowland A, Miners JO.
    Br J Clin Pharmacol; 2013 Oct; 76(4):587-602. PubMed ID: 23362865
    [Abstract] [Full Text] [Related]

  • 3. Identification of enzymes responsible for the N-oxidation of darexaban glucuronide, the pharmacologically active metabolite of darexaban, and the glucuronidation of darexaban N-oxides in human liver microsomes.
    Shiraga T, Yajima K, Teragaki T, Suzuki K, Hashimoto T, Iwatsubo T, Miyashita A, Usui T.
    Biol Pharm Bull; 2012 Oct; 35(3):413-21. PubMed ID: 22382330
    [Abstract] [Full Text] [Related]

  • 4. Drug metabolism by flavin-containing monooxygenases of human and mouse.
    Phillips IR, Shephard EA.
    Expert Opin Drug Metab Toxicol; 2017 Feb; 13(2):167-181. PubMed ID: 27678284
    [Abstract] [Full Text] [Related]

  • 5. Regioselective oxidation of phospho-NSAIDs by human cytochrome P450 and flavin monooxygenase isoforms: implications for their pharmacokinetic properties and safety.
    Xie G, Wong CC, Cheng KW, Huang L, Constantinides PP, Rigas B.
    Br J Pharmacol; 2012 Sep; 167(1):222-32. PubMed ID: 22489789
    [Abstract] [Full Text] [Related]

  • 6. [Drug glucuronidation and disposition in brain].
    Zhang ZQ, Sheng L, Li Y.
    Yao Xue Xue Bao; 2016 Nov; 51(11):1674-80. PubMed ID: 29908109
    [Abstract] [Full Text] [Related]

  • 7. Direct comparison of UDP-glucuronosyltransferase and cytochrome P450 activities in human liver microsomes, plated and suspended primary human hepatocytes from five liver donors.
    den Braver-Sewradj SP, den Braver MW, Baze A, Decorde J, Fonsi M, Bachellier P, Vermeulen NPE, Commandeur JNM, Richert L, Vos JC.
    Eur J Pharm Sci; 2017 Nov 15; 109():96-110. PubMed ID: 28778465
    [Abstract] [Full Text] [Related]

  • 8. Modulation of UDP-glucuronosyltransferase activity by protein-protein association.
    Ishii Y, Takeda S, Yamada H.
    Drug Metab Rev; 2010 Feb 15; 42(1):145-58. PubMed ID: 19817679
    [Abstract] [Full Text] [Related]

  • 9. Quantitative prediction of human intestinal glucuronidation effects on intestinal availability of UDP-glucuronosyltransferase substrates using in vitro data.
    Nakamori F, Naritomi Y, Hosoya K, Moriguchi H, Tetsuka K, Furukawa T, Kadono K, Yamano K, Terashita S, Teramura T.
    Drug Metab Dispos; 2012 Sep 15; 40(9):1771-7. PubMed ID: 22685216
    [Abstract] [Full Text] [Related]

  • 10. Nicotine-N'-Oxidation by Flavin Monooxygenase Enzymes.
    Perez-Paramo YX, Chen G, Ashmore JH, Watson CJW, Nasrin S, Adams-Haduch J, Wang R, Gao YT, Koh WP, Yuan JM, Lazarus P.
    Cancer Epidemiol Biomarkers Prev; 2019 Feb 15; 28(2):311-320. PubMed ID: 30381441
    [Abstract] [Full Text] [Related]

  • 11. Metabolism of dipropyl disulfide by rat liver phase I and phase II enzymes and by isolated perfused rat liver.
    Teyssier C, Siess MH.
    Drug Metab Dispos; 2000 Jun 15; 28(6):648-54. PubMed ID: 10820136
    [Abstract] [Full Text] [Related]

  • 12. A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models.
    Uno Y, Shimizu M, Yamazaki H.
    Biochem Pharmacol; 2024 Oct 15; 228():116124. PubMed ID: 38490520
    [Abstract] [Full Text] [Related]

  • 13. Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism.
    Krueger SK, Williams DE.
    Pharmacol Ther; 2005 Jun 15; 106(3):357-87. PubMed ID: 15922018
    [Abstract] [Full Text] [Related]

  • 14. In vitro hepatic metabolism of cediranib, a potent vascular endothelial growth factor tyrosine kinase inhibitor: interspecies comparison and human enzymology.
    Schulz-Utermoehl T, Spear M, Pollard CR, Pattison C, Rollison H, Sarda S, Ward M, Bushby N, Jordan A, Harrison M.
    Drug Metab Dispos; 2010 Oct 15; 38(10):1688-97. PubMed ID: 20634336
    [Abstract] [Full Text] [Related]

  • 15. Protein-protein interactions between rat hepatic cytochromes P450 (P450s) and UDP-glucuronosyltransferases (UGTs): evidence for the functionally active UGT in P450-UGT complex.
    Ishii Y, Iwanaga M, Nishimura Y, Takeda S, Ikushiro S, Nagata K, Yamazoe Y, Mackenzie PI, Yamada H.
    Drug Metab Pharmacokinet; 2007 Oct 15; 22(5):367-76. PubMed ID: 17965520
    [Abstract] [Full Text] [Related]

  • 16. Metabolic interactions of rosmarinic acid with human cytochrome P450 monooxygenases and uridine diphosphate glucuronosyltransferases.
    Kim SB, Kim KS, Kim DD, Yoon IS.
    Biomed Pharmacother; 2019 Feb 15; 110():111-117. PubMed ID: 30466000
    [Abstract] [Full Text] [Related]

  • 17. In Vitro Characterization of Ertugliflozin Metabolism by UDP-Glucuronosyltransferase and Cytochrome P450 Enzymes.
    Lapham K, Callegari E, Cianfrogna J, Lin J, Niosi M, Orozco CC, Sharma R, Goosen TC.
    Drug Metab Dispos; 2020 Dec 15; 48(12):1350-1363. PubMed ID: 33020067
    [Abstract] [Full Text] [Related]

  • 18. Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios.
    Williams JA, Hyland R, Jones BC, Smith DA, Hurst S, Goosen TC, Peterkin V, Koup JR, Ball SE.
    Drug Metab Dispos; 2004 Nov 15; 32(11):1201-8. PubMed ID: 15304429
    [Abstract] [Full Text] [Related]

  • 19. The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthion.
    Leoni C, Buratti FM, Testai E.
    Toxicol Appl Pharmacol; 2008 Dec 01; 233(2):343-52. PubMed ID: 18845175
    [Abstract] [Full Text] [Related]

  • 20. Some distinctions between flavin-containing and cytochrome P450 monooxygenases.
    Cashman JR.
    Biochem Biophys Res Commun; 2005 Dec 09; 338(1):599-604. PubMed ID: 16112078
    [Abstract] [Full Text] [Related]

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