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Journal Abstract Search
346 related items for PubMed ID: 32549218
1. Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5. Han H, Li C, Li M, Yang L, Zhao S, Wang Z, Liu H, Liu D. Molecules; 2020 Jun 15; 25(12):. PubMed ID: 32549218 [Abstract] [Full Text] [Related]
2. Discovery and characterization of small molecule SIRT3-specific inhibitors as revealed by mass spectrometry. Loharch S, Chhabra S, Kumar A, Swarup S, Parkesh R. Bioorg Chem; 2021 May 15; 110():104768. PubMed ID: 33676042 [Abstract] [Full Text] [Related]
3. Design, synthesis and structure-activity relationship studies of novel sirtuin 2 (SIRT2) inhibitors with a benzamide skeleton. Sakai T, Matsumoto Y, Ishikawa M, Sugita K, Hashimoto Y, Wakai N, Kitao A, Morishita E, Toyoshima C, Hayashi T, Akiyama T. Bioorg Med Chem; 2015 Jan 15; 23(2):328-39. PubMed ID: 25515955 [Abstract] [Full Text] [Related]
6. Hit-to-lead optimization on aryloxybenzamide derivative virtual screening hit against SIRT. Yagci S, Gozelle M, Kaya SG, Ozkan Y, Aksel AB, Bakar-Ates F, Dundar Y, Eren G. Bioorg Med Chem; 2021 Jan 15; 30():115961. PubMed ID: 33360574 [Abstract] [Full Text] [Related]
7. Design, synthesis, in-vitro evaluation and molecular docking studies of novel indole derivatives as inhibitors of SIRT1 and SIRT2. Manjula R, Gokhale N, Unni S, Deshmukh P, Reddyrajula R, Srinivas Bharath MM, Dalimba U, Padmanabhan B. Bioorg Chem; 2019 Nov 15; 92():103281. PubMed ID: 31561106 [Abstract] [Full Text] [Related]
10. Recent advances in inhibitors of sirtuin1/2: an update and perspective. Zhou Z, Ma T, Zhu Q, Xu Y, Zha X. Future Med Chem; 2018 Apr 01; 10(8):907-934. PubMed ID: 29642711 [Abstract] [Full Text] [Related]
14. Kinetic and Structural Basis for Acyl-Group Selectivity and NAD(+) Dependence in Sirtuin-Catalyzed Deacylation. Feldman JL, Dittenhafer-Reed KE, Kudo N, Thelen JN, Ito A, Yoshida M, Denu JM. Biochemistry; 2015 May 19; 54(19):3037-3050. PubMed ID: 25897714 [Abstract] [Full Text] [Related]
16. The plasticizer BBP selectively inhibits epigenetic regulator sirtuins. Zhang J, Ali HI, Bedi YS, Choudhury M. Toxicology; 2015 Dec 02; 338():130-41. PubMed ID: 26520405 [Abstract] [Full Text] [Related]
17. A bicyclic pentapeptide-based highly potent and selective pan-SIRT1/2/3 inhibitor harboring Nε-thioacetyl-lysine. Li R, Yan L, Sun X, Zheng W. Bioorg Med Chem; 2020 Apr 01; 28(7):115356. PubMed ID: 32067892 [Abstract] [Full Text] [Related]
18. Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5. Suenkel B, Valente S, Zwergel C, Weiss S, Di Bello E, Fioravanti R, Aventaggiato M, Amorim JA, Garg N, Kumar S, Lombard DB, Hu T, Singh PK, Tafani M, Palmeira CM, Sinclair D, Mai A, Steegborn C. J Med Chem; 2022 Oct 27; 65(20):14015-14031. PubMed ID: 36228194 [Abstract] [Full Text] [Related]
19. Structure-based discovery of new selective small-molecule sirtuin 5 inhibitors. Liu S, Ji S, Yu ZJ, Wang HL, Cheng X, Li WJ, Jing L, Yu Y, Chen Q, Yang LL, Li GB, Wu Y. Chem Biol Drug Des; 2018 Jan 27; 91(1):257-268. PubMed ID: 28756638 [Abstract] [Full Text] [Related]