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Journal Abstract Search

395 related items for PubMed ID: 32615502

  • 1. PTG-0861: A novel HDAC6-selective inhibitor as a therapeutic strategy in acute myeloid leukaemia.
    Gawel JM, Shouksmith AE, Raouf YS, Nawar N, Toutah K, Bukhari S, Manaswiyoungkul P, Olaoye OO, Israelian J, Radu TB, Cabral AD, Sina D, Sedighi A, de Araujo ED, Gunning PT.
    Eur J Med Chem; 2020 Sep 01; 201():112411. PubMed ID: 32615502
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  • 2. Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo.
    Ojha R, Nepali K, Chen CH, Chuang KH, Wu TY, Lin TE, Hsu KC, Chao MW, Lai MJ, Lin MH, Huang HL, Chang CD, Pan SL, Chen MC, Liou JP.
    Eur J Med Chem; 2020 Mar 15; 190():112086. PubMed ID: 32058238
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  • 3. Discovery of Novel Histone Deacetylase 6 (HDAC6) Inhibitors with Enhanced Antitumor Immunity of Anti-PD-L1 Immunotherapy in Melanoma.
    Peng X, Li L, Chen J, Ren Y, Liu J, Yu Z, Cao H, Chen J.
    J Med Chem; 2022 Feb 10; 65(3):2434-2457. PubMed ID: 35043615
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  • 5. Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia.
    Toutah K, Nawar N, Timonen S, Sorger H, Raouf YS, Bukhari S, von Jan J, Ianevski A, Gawel JM, Olaoye OO, Geletu M, Abdeldayem A, Israelian J, Radu TB, Sedighi A, Bhatti MN, Hassan MM, Manaswiyoungkul P, Shouksmith AE, Neubauer HA, de Araujo ED, Aittokallio T, Krämer OH, Moriggl R, Mustjoki S, Herling M, Gunning PT.
    J Med Chem; 2021 Jun 24; 64(12):8486-8509. PubMed ID: 34101461
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  • 6. The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity.
    Negmeldin AT, Knoff JR, Pflum MKH.
    Eur J Med Chem; 2018 Jan 01; 143():1790-1806. PubMed ID: 29150330
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  • 10. Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated.
    Géraldy M, Morgen M, Sehr P, Steimbach RR, Moi D, Ridinger J, Oehme I, Witt O, Malz M, Nogueira MS, Koch O, Gunkel N, Miller AK.
    J Med Chem; 2019 May 09; 62(9):4426-4443. PubMed ID: 30964290
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  • 12. Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma.
    Nawar N, Bukhari S, Adile AA, Suk Y, Manaswiyoungkul P, Toutah K, Olaoye OO, Raouf YS, Sedighi A, Garcha HK, Hassan MM, Gwynne W, Israelian J, Radu TB, Geletu M, Abdeldayem A, Gawel JM, Cabral AD, Venugopal C, de Araujo ED, Singh SK, Gunning PT.
    J Med Chem; 2022 Feb 24; 65(4):3193-3217. PubMed ID: 35119267
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  • 13. Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors.
    Leonhardt M, Sellmer A, Krämer OH, Dove S, Elz S, Kraus B, Beyer M, Mahboobi S.
    Eur J Med Chem; 2018 May 25; 152():329-357. PubMed ID: 29738953
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  • 14. Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors.
    Sellmer A, Stangl H, Beyer M, Grünstein E, Leonhardt M, Pongratz H, Eichhorn E, Elz S, Striegl B, Jenei-Lanzl Z, Dove S, Straub RH, Krämer OH, Mahboobi S.
    J Med Chem; 2018 Apr 26; 61(8):3454-3477. PubMed ID: 29589441
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  • 15. Discovery of Thieno[2,3-d]pyrimidine-Based Hydroxamic Acid Derivatives as Bromodomain-Containing Protein 4/Histone Deacetylase Dual Inhibitors Induce Autophagic Cell Death in Colorectal Carcinoma Cells.
    Pan Z, Li X, Wang Y, Jiang Q, Jiang L, Zhang M, Zhang N, Wu F, Liu B, He G.
    J Med Chem; 2020 Apr 09; 63(7):3678-3700. PubMed ID: 32153186
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  • 16. Discovery of 1,2,4-oxadiazole-Containing hydroxamic acid derivatives as histone deacetylase inhibitors potential application in cancer therapy.
    Yang Z, Shen M, Tang M, Zhang W, Cui X, Zhang Z, Pei H, Li Y, Hu M, Bai P, Chen L.
    Eur J Med Chem; 2019 Sep 15; 178():116-130. PubMed ID: 31177073
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  • 17. Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors.
    Porter NJ, Mahendran A, Breslow R, Christianson DW.
    Proc Natl Acad Sci U S A; 2017 Dec 19; 114(51):13459-13464. PubMed ID: 29203661
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  • 18. Development of selective HDAC6 inhibitors with in vitro and in vivo anti-multiple myeloma activity.
    Li S, Zhao C, Zhang G, Xu Q, Liu Q, Zhao W, James Chou C, Zhang Y.
    Bioorg Chem; 2021 Nov 19; 116():105278. PubMed ID: 34474303
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  • 19. Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs).
    Linciano P, Benedetti R, Pinzi L, Russo F, Chianese U, Sorbi C, Altucci L, Rastelli G, Brasili L, Franchini S.
    Bioorg Chem; 2021 Jan 19; 106():104462. PubMed ID: 33213894
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  • 20. Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.
    Vögerl K, Ong N, Senger J, Herp D, Schmidtkunz K, Marek M, Müller M, Bartel K, Shaik TB, Porter NJ, Robaa D, Christianson DW, Romier C, Sippl W, Jung M, Bracher F.
    J Med Chem; 2019 Feb 14; 62(3):1138-1166. PubMed ID: 30645113
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