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266 related items for PubMed ID: 32698188

  • 1. Structure of the human sodium leak channel NALCN.
    Kschonsak M, Chua HC, Noland CL, Weidling C, Clairfeuille T, Bahlke OØ, Ameen AO, Li ZR, Arthur CP, Ciferri C, Pless SA, Payandeh J.
    Nature; 2020 Nov; 587(7833):313-318. PubMed ID: 32698188
    [Abstract] [Full Text] [Related]

  • 2. Structure of the human sodium leak channel NALCN in complex with FAM155A.
    Xie J, Ke M, Xu L, Lin S, Huang J, Zhang J, Yang F, Wu J, Yan Z.
    Nat Commun; 2020 Nov 17; 11(1):5831. PubMed ID: 33203861
    [Abstract] [Full Text] [Related]

  • 3. Structure of voltage-modulated sodium-selective NALCN-FAM155A channel complex.
    Kang Y, Wu JX, Chen L.
    Nat Commun; 2020 Dec 03; 11(1):6199. PubMed ID: 33273469
    [Abstract] [Full Text] [Related]

  • 4. Structural architecture of the human NALCN channelosome.
    Kschonsak M, Chua HC, Weidling C, Chakouri N, Noland CL, Schott K, Chang T, Tam C, Patel N, Arthur CP, Leitner A, Ben-Johny M, Ciferri C, Pless SA, Payandeh J.
    Nature; 2022 Mar 03; 603(7899):180-186. PubMed ID: 34929720
    [Abstract] [Full Text] [Related]

  • 5. New insights into the physiology and pathophysiology of the atypical sodium leak channel NALCN.
    Monteil A, Guérineau NC, Gil-Nagel A, Parra-Diaz P, Lory P, Senatore A.
    Physiol Rev; 2024 Jan 01; 104(1):399-472. PubMed ID: 37615954
    [Abstract] [Full Text] [Related]

  • 6. Structure and mechanism of NALCN-FAM155A-UNC79-UNC80 channel complex.
    Kang Y, Chen L.
    Nat Commun; 2022 May 12; 13(1):2639. PubMed ID: 35550517
    [Abstract] [Full Text] [Related]

  • 7. Functional expression of CLIFAHDD and IHPRF pathogenic variants of the NALCN channel in neuronal cells reveals both gain- and loss-of-function properties.
    Bouasse M, Impheng H, Servant Z, Lory P, Monteil A.
    Sci Rep; 2019 Aug 13; 9(1):11791. PubMed ID: 31409833
    [Abstract] [Full Text] [Related]

  • 8. Unplugging lateral fenestrations of NALCN reveals a hidden drug binding site within the pore region.
    Schott K, Usher SG, Serra O, Carnevale V, Pless SA, Chua HC.
    Proc Natl Acad Sci U S A; 2024 May 28; 121(22):e2401591121. PubMed ID: 38787877
    [Abstract] [Full Text] [Related]

  • 9. A uniquely adaptable pore is consistent with NALCN being an ion sensor.
    Senatore A, Spafford JD.
    Channels (Austin); 2013 May 28; 7(2):60-8. PubMed ID: 23442378
    [Abstract] [Full Text] [Related]

  • 10. Nalcn Is a "Leak" Sodium Channel That Regulates Excitability of Brainstem Chemosensory Neurons and Breathing.
    Shi Y, Abe C, Holloway BB, Shu S, Kumar NN, Weaver JL, Sen J, Perez-Reyes E, Stornetta RL, Guyenet PG, Bayliss DA.
    J Neurosci; 2016 Aug 03; 36(31):8174-87. PubMed ID: 27488637
    [Abstract] [Full Text] [Related]

  • 11. The neuronal channel NALCN contributes resting sodium permeability and is required for normal respiratory rhythm.
    Lu B, Su Y, Das S, Liu J, Xia J, Ren D.
    Cell; 2007 Apr 20; 129(2):371-83. PubMed ID: 17448995
    [Abstract] [Full Text] [Related]

  • 12. Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex.
    Wie J, Bharthur A, Wolfgang M, Narayanan V, Ramsey K, C4RCD Research Group, Aranda K, Zhang Q, Zhou Y, Ren D.
    Nat Commun; 2020 Jul 03; 11(1):3351. PubMed ID: 32620897
    [Abstract] [Full Text] [Related]

  • 13. Unplugging lateral fenestrations of NALCN reveals a hidden drug binding site within the pore module.
    Schott K, Usher SG, Serra O, Carnevale V, Pless SA, Chua HC.
    bioRxiv; 2024 Jan 28. PubMed ID: 38328210
    [Abstract] [Full Text] [Related]

  • 14. Methylation determines the extracellular calcium sensitivity of the leak channel NALCN in hippocampal dentate granule cells.
    Lee SY, Vuong TA, Wen X, Jeong HJ, So HK, Kwon I, Kang JS, Cho H.
    Exp Mol Med; 2019 Oct 10; 51(10):1-14. PubMed ID: 31601786
    [Abstract] [Full Text] [Related]

  • 15. NALCN ion channels have alternative selectivity filters resembling calcium channels or sodium channels.
    Senatore A, Monteil A, van Minnen J, Smit AB, Spafford JD.
    PLoS One; 2013 Oct 10; 8(1):e55088. PubMed ID: 23383067
    [Abstract] [Full Text] [Related]

  • 16. Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies).
    Bramswig NC, Bertoli-Avella AM, Albrecht B, Al Aqeel AI, Alhashem A, Al-Sannaa N, Bah M, Bröhl K, Depienne C, Dorison N, Doummar D, Ehmke N, Elbendary HM, Gorokhova S, Héron D, Horn D, James K, Keren B, Kuechler A, Ismail S, Issa MY, Marey I, Mayer M, McEvoy-Venneri J, Megarbane A, Mignot C, Mohamed S, Nava C, Philip N, Ravix C, Rolfs A, Sadek AA, Segebrecht L, Stanley V, Trautman C, Valence S, Villard L, Wieland T, Engels H, Strom TM, Zaki MS, Gleeson JG, Lüdecke HJ, Bauer P, Wieczorek D.
    Hum Genet; 2018 Sep 10; 137(9):753-768. PubMed ID: 30167850
    [Abstract] [Full Text] [Related]

  • 17. Na+-Leak Channel, Non-Selective (NALCN) Regulates Myometrial Excitability and Facilitates Successful Parturition.
    Reinl EL, Zhao P, Wu W, Ma X, Amazu C, Bok R, Hurt KJ, Wang Y, England SK.
    Cell Physiol Biochem; 2018 Sep 10; 48(2):503-515. PubMed ID: 30021195
    [Abstract] [Full Text] [Related]

  • 18. The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium.
    Chua HC, Wulf M, Weidling C, Rasmussen LP, Pless SA.
    Sci Adv; 2020 Apr 10; 6(17):eaaz3154. PubMed ID: 32494638
    [Abstract] [Full Text] [Related]

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