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Journal Abstract Search

193 related items for PubMed ID: 32703450

  • 1.
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  • 2. Somatic MAP2K1 Mutations Are Associated with Extracranial Arteriovenous Malformation.
    Couto JA, Huang AY, Konczyk DJ, Goss JA, Fishman SJ, Mulliken JB, Warman ML, Greene AK.
    Am J Hum Genet; 2017 Mar 02; 100(3):546-554. PubMed ID: 28190454
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  • 4. Endothelial cell expression of mutant Map2k1 causes vascular malformations in mice.
    Smits PJ, Sudduth CL, Konczyk DJ, Cheng YS, Vivero MP, Kozakewich HPW, Warman ML, Greene AK.
    Angiogenesis; 2023 Feb 02; 26(1):97-105. PubMed ID: 35972708
    [Abstract] [Full Text] [Related]

  • 5. Arteriovenous Malformation MAP2K1 Mutation Causes Local Cartilage Overgrowth by a Cell-Non Autonomous Mechanism.
    Konczyk DJ, Goss JA, Smits PJ, Sudduth CL, Al-Ibraheemi A, Greene AK.
    Sci Rep; 2020 Mar 10; 10(1):4428. PubMed ID: 32157142
    [Abstract] [Full Text] [Related]

  • 6. Intramuscular fast-flow vascular anomaly contains somatic MAP2K1 and KRAS mutations.
    Goss JA, Konczyk DJ, Smits PJ, Kozakewich HPW, Alomari AI, Al-Ibraheemi A, Taghinia AH, Dickie BH, Adams DM, Fishman SJ, Mulliken JB, Warman ML, Greene AK.
    Angiogenesis; 2019 Nov 10; 22(4):547-552. PubMed ID: 31486960
    [Abstract] [Full Text] [Related]

  • 7. Arteriovenous malformation associated with a HRAS mutation.
    Konczyk DJ, Goss JA, Smits PJ, Huang AY, Al-Ibraheemi A, Sudduth CL, Warman ML, Greene AK.
    Hum Genet; 2019 Dec 10; 138(11-12):1419-1421. PubMed ID: 31637524
    [Abstract] [Full Text] [Related]

  • 8. Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy.
    Al-Olabi L, Polubothu S, Dowsett K, Andrews KA, Stadnik P, Joseph AP, Knox R, Pittman A, Clark G, Baird W, Bulstrode N, Glover M, Gordon K, Hargrave D, Huson SM, Jacques TS, James G, Kondolf H, Kangesu L, Keppler-Noreuil KM, Khan A, Lindhurst MJ, Lipson M, Mansour S, O'Hara J, Mahon C, Mosica A, Moss C, Murthy A, Ong J, Parker VE, Rivière JB, Sapp JC, Sebire NJ, Shah R, Sivakumar B, Thomas A, Virasami A, Waelchli R, Zeng Z, Biesecker LG, Barnacle A, Topf M, Semple RK, Patton EE, Kinsler VA.
    J Clin Invest; 2018 Apr 02; 128(4):1496-1508. PubMed ID: 29461977
    [Abstract] [Full Text] [Related]

  • 9. Heterogeneity of the signal transduction pathways for VEGF-induced MAPKs activation in human vascular endothelial cells.
    Yashima R, Abe M, Tanaka K, Ueno H, Shitara K, Takenoshita S, Sato Y.
    J Cell Physiol; 2001 Aug 02; 188(2):201-10. PubMed ID: 11424087
    [Abstract] [Full Text] [Related]

  • 10. Angiopoietin-2 Inhibition Rescues Arteriovenous Malformation in a Smad4 Hereditary Hemorrhagic Telangiectasia Mouse Model.
    Crist AM, Zhou X, Garai J, Lee AR, Thoele J, Ullmer C, Klein C, Zabaleta J, Meadows SM.
    Circulation; 2019 Apr 23; 139(17):2049-2063. PubMed ID: 30744395
    [Abstract] [Full Text] [Related]

  • 11. Germline Loss-of-Function Mutations in EPHB4 Cause a Second Form of Capillary Malformation-Arteriovenous Malformation (CM-AVM2) Deregulating RAS-MAPK Signaling.
    Amyere M, Revencu N, Helaers R, Pairet E, Baselga E, Cordisco M, Chung W, Dubois J, Lacour JP, Martorell L, Mazereeuw-Hautier J, Pyeritz RE, Amor DJ, Bisdorff A, Blei F, Bombei H, Dompmartin A, Brooks D, Dupont J, González-Enseñat MA, Frieden I, Gérard M, Kvarnung M, Hanson-Kahn AK, Hudgins L, Léauté-Labrèze C, McCuaig C, Metry D, Parent P, Paul C, Petit F, Phan A, Quere I, Salhi A, Turner A, Vabres P, Vicente A, Wargon O, Watanabe S, Weibel L, Wilson A, Willing M, Mulliken JB, Boon LM, Vikkula M.
    Circulation; 2017 Sep 12; 136(11):1037-1048. PubMed ID: 28687708
    [Abstract] [Full Text] [Related]

  • 12. A human model of arteriovenous malformation (AVM)-on-a-chip reproduces key disease hallmarks and enables drug testing in perfused human vessel networks.
    Soon K, Li M, Wu R, Zhou A, Khosraviani N, Turner WD, Wythe JD, Fish JE, Nunes SS.
    Biomaterials; 2022 Sep 12; 288():121729. PubMed ID: 35999080
    [Abstract] [Full Text] [Related]

  • 13. Endothelial exposure to hypoxia induces Egr-1 expression involving PKCalpha-mediated Ras/Raf-1/ERK1/2 pathway.
    Lo LW, Cheng JJ, Chiu JJ, Wung BS, Liu YC, Wang DL.
    J Cell Physiol; 2001 Sep 12; 188(3):304-12. PubMed ID: 11473356
    [Abstract] [Full Text] [Related]

  • 14. Somatic Mosaicism in the Pathogenesis of de novo Cerebral Arteriovenous Malformations: A Paradigm Shift Implicating the RAS-MAPK Signaling Cascade.
    Peterson K, Coffman S, Zehri A, Anzalone A, Xiang Z, Wolfe S.
    Cerebrovasc Dis; 2021 Sep 12; 50(2):231-238. PubMed ID: 33556951
    [Abstract] [Full Text] [Related]

  • 15. Somatic RIT1 delins in arteriovenous malformations hyperactivate RAS-MAPK signaling amenable to MEK inhibition.
    Kapp FG, Bazgir F, Mahammadzade N, Mehrabipour M, Vassella E, Bernhard SM, Döring Y, Holm A, Karow A, Seebauer C, Platz Batista da Silva N, Wohlgemuth WA, Oppenheimer A, Kröning P, Niemeyer CM, Schanze D, Zenker M, Eng W, Ahmadian MR, Baumgartner I, Rössler J.
    Angiogenesis; 2024 Nov 12; 27(4):739-752. PubMed ID: 38969873
    [Abstract] [Full Text] [Related]

  • 16. Basic fibroblast growth factor inhibits radiation-induced apoptosis of HUVECs. II. The RAS/MAPK pathway and phosphorylation of BAD at serine 112.
    Gu Q, Wang D, Wang X, Peng R, Liu J, Deng H, Wang Z, Jiang T.
    Radiat Res; 2004 Jun 12; 161(6):703-11. PubMed ID: 15161349
    [Abstract] [Full Text] [Related]

  • 17. Somatic Gain of KRAS Function in the Endothelium Is Sufficient to Cause Vascular Malformations That Require MEK but Not PI3K Signaling.
    Fish JE, Flores Suarez CP, Boudreau E, Herman AM, Gutierrez MC, Gustafson D, DiStefano PV, Cui M, Chen Z, De Ruiz KB, Schexnayder TS, Ward CS, Radovanovic I, Wythe JD.
    Circ Res; 2020 Aug 28; 127(6):727-743. PubMed ID: 32552404
    [Abstract] [Full Text] [Related]

  • 18. Endothelial k-RasV12 Expression Induces Capillary Deficiency Attributable to Marked Tube Network Expansion Coupled to Reduced Pericytes and Basement Membranes.
    Sun Z, Kemp SS, Lin PK, Aguera KN, Davis GE.
    Arterioscler Thromb Vasc Biol; 2022 Feb 28; 42(2):205-222. PubMed ID: 34879709
    [Abstract] [Full Text] [Related]

  • 19. Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling.
    Jin Y, Muhl L, Burmakin M, Wang Y, Duchez AC, Betsholtz C, Arthur HM, Jakobsson L.
    Nat Cell Biol; 2017 Jun 28; 19(6):639-652. PubMed ID: 28530660
    [Abstract] [Full Text] [Related]

  • 20. Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells.
    Cheng TH, Shih NL, Chen SY, Loh SH, Cheng PY, Tsai CS, Liu SH, Wang DL, Chen JJ.
    J Mol Cell Cardiol; 2001 Oct 28; 33(10):1805-14. PubMed ID: 11603923
    [Abstract] [Full Text] [Related]

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