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185 related items for PubMed ID: 32721391

  • 1. PAK5 promotes the cell stemness ability by phosphorylating SOX2 in lung squamous cell carcinomas.
    Bao Z, Ji W, Yang Y, Chen Z, Li Z, Wang K, Lu T, Yu Y, Xia W, Lu S.
    Exp Cell Res; 2020 Oct 15; 395(2):112187. PubMed ID: 32721391
    [Abstract] [Full Text] [Related]

  • 2. Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture.
    Chen S, Giannakou A, Wyman S, Gruzas J, Golas J, Zhong W, Loreth C, Sridharan L, Yamin TT, Damelin M, Geles KG.
    Proc Natl Acad Sci U S A; 2018 Dec 11; 115(50):E11671-E11680. PubMed ID: 30487219
    [Abstract] [Full Text] [Related]

  • 3. EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer.
    Singh S, Trevino J, Bora-Singhal N, Coppola D, Haura E, Altiok S, Chellappan SP.
    Mol Cancer; 2012 Sep 25; 11():73. PubMed ID: 23009336
    [Abstract] [Full Text] [Related]

  • 4. Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer.
    Schaal CM, Bora-Singhal N, Kumar DM, Chellappan SP.
    Mol Cancer; 2018 Oct 15; 17(1):149. PubMed ID: 30322398
    [Abstract] [Full Text] [Related]

  • 5. p21-activated kinase 2 binds to transcription factor SOX2 and up-regulates DEK to promote the progression of lung squamous cell carcinoma.
    Xie S, Wan X, Chen S, Hu Y, Liu X.
    Lab Invest; 2022 Oct 15; 102(10):1109-1120. PubMed ID: 35821094
    [Abstract] [Full Text] [Related]

  • 6. Jmjd2c maintains the ALDHbri+ cancer stemness with transcription factor SOX2 in lung squamous cell carcinoma.
    Wang M, Hu Y, Cai F, Guo L, Mao Y, Zhang Y.
    Cancer Biol Ther; 2024 Dec 31; 25(1):2373447. PubMed ID: 38975736
    [Abstract] [Full Text] [Related]

  • 7. PAK5-mediated phosphorylation and nuclear translocation of NF-κB-p65 promotes breast cancer cell proliferation in vitro and in vivo.
    Zhang YC, Huo FC, Wei LL, Gong CC, Pan YJ, Mou J, Pei DS.
    J Exp Clin Cancer Res; 2017 Oct 17; 36(1):146. PubMed ID: 29041983
    [Abstract] [Full Text] [Related]

  • 8. Epigenomic Profiling Discovers Trans-lineage SOX2 Partnerships Driving Tumor Heterogeneity in Lung Squamous Cell Carcinoma.
    Sato T, Yoo S, Kong R, Sinha A, Chandramani-Shivalingappa P, Patel A, Fridrikh M, Nagano O, Masuko T, Beasley MB, Powell CA, Zhu J, Watanabe H.
    Cancer Res; 2019 Dec 15; 79(24):6084-6100. PubMed ID: 31551362
    [Abstract] [Full Text] [Related]

  • 9. Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma.
    Fang WT, Fan CC, Li SM, Jang TH, Lin HP, Shih NY, Chen CH, Wang TY, Huang SF, Lee AY, Liu YL, Tsai FY, Huang CT, Yang SJ, Yen LJ, Chuu CP, Chen CY, Hsiung CA, Chang JY, Wang LH, Chang IS, Jiang SS.
    Int J Cancer; 2014 Aug 15; 135(4):809-19. PubMed ID: 24477565
    [Abstract] [Full Text] [Related]

  • 10. Self-restricted circular RNA circSOX2 suppressed the malignant progression in SOX2-amplified LUSC.
    Liang Y, Wang N, Zhang Y, Jiang W, Fang C, Feng Y, Ma H, Jiang F, Dong G.
    Cell Death Dis; 2022 Oct 15; 13(10):873. PubMed ID: 36243874
    [Abstract] [Full Text] [Related]

  • 11. PAK5-mediated E47 phosphorylation promotes epithelial-mesenchymal transition and metastasis of colon cancer.
    Zhu G, Li X, Guo B, Ke Q, Dong M, Li F.
    Oncogene; 2016 Apr 14; 35(15):1943-54. PubMed ID: 26212009
    [Abstract] [Full Text] [Related]

  • 12. PAK5 Induces EMT and Promotes Cell Migration and Invasion by Activating the PI3K/AKT Pathway in Ovarian Cancer.
    Li D, Pan Y, Huang Y, Zhang P, Fang X.
    Anal Cell Pathol (Amst); 2018 Apr 14; 2018():8073124. PubMed ID: 30245957
    [Abstract] [Full Text] [Related]

  • 13. Sex-Determining Region Y-box 2 Promotes Growth of Lung Squamous Cell Carcinoma and Directly Targets Cyclin D1.
    Li C, He B, Huang C, Yang H, Cao L, Huang J, Hu C.
    DNA Cell Biol; 2017 Apr 14; 36(4):264-272. PubMed ID: 28151013
    [Abstract] [Full Text] [Related]

  • 14. SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma.
    Fukazawa T, Guo M, Ishida N, Yamatsuji T, Takaoka M, Yokota E, Haisa M, Miyake N, Ikeda T, Okui T, Takigawa N, Maeda Y, Naomoto Y.
    Sci Rep; 2016 Feb 05; 6():20113. PubMed ID: 26846300
    [Abstract] [Full Text] [Related]

  • 15. Chromosome 3q26 Gain Is an Early Event Driving Coordinated Overexpression of the PRKCI, SOX2, and ECT2 Oncogenes in Lung Squamous Cell Carcinoma.
    Liu Y, Yin N, Wang X, Khoor A, Sambandam V, Ghosh AB, Fields ZA, Murray NR, Justilien V, Fields AP.
    Cell Rep; 2020 Jan 21; 30(3):771-782.e6. PubMed ID: 31968252
    [Abstract] [Full Text] [Related]

  • 16. The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinoma.
    Justilien V, Walsh MP, Ali SA, Thompson EA, Murray NR, Fields AP.
    Cancer Cell; 2014 Feb 10; 25(2):139-51. PubMed ID: 24525231
    [Abstract] [Full Text] [Related]

  • 17. Upregulation of P21-Activated Kinase 1 (PAK1)/CREB Axis in Squamous Non-Small Cell Lung Carcinoma.
    Chung JH, Kim DH, Kim YS, Son BS, Kim D, Hwang C, Shin D, Noh SG, Han JH, Kim DK, Kim JH, Koo JS, Chung HY, Yoon SH.
    Cell Physiol Biochem; 2018 Feb 10; 50(1):304-316. PubMed ID: 30282071
    [Abstract] [Full Text] [Related]

  • 18. XIAP Limits Autophagic Degradation of Sox2 and Is A Therapeutic Target in Nasopharyngeal Carcinoma Stem Cells.
    Ji J, Yu Y, Li ZL, Chen MY, Deng R, Huang X, Wang GF, Zhang MX, Yang Q, Ravichandran S, Feng GK, Xu XL, Yang CL, Qiu MZ, Jiao L, Yang D, Zhu XF.
    Theranostics; 2018 Feb 10; 8(6):1494-1510. PubMed ID: 29556337
    [Abstract] [Full Text] [Related]

  • 19. BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma.
    Lazarus KA, Hadi F, Zambon E, Bach K, Santolla MF, Watson JK, Correia LL, Das M, Ugur R, Pensa S, Becker L, Campos LS, Ladds G, Liu P, Evan GI, McCaughan FM, Le Quesne J, Lee JH, Calado D, Khaled WT.
    Nat Commun; 2018 Aug 20; 9(1):3327. PubMed ID: 30127402
    [Abstract] [Full Text] [Related]

  • 20. TMED3 promotes the progression and development of lung squamous cell carcinoma by regulating EZR.
    Xie A, Xu X, Kuang P, Zhang L, Yu F.
    Cell Death Dis; 2021 Aug 24; 12(9):804. PubMed ID: 34429402
    [Abstract] [Full Text] [Related]

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