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Journal Abstract Search

259 related items for PubMed ID: 32721780

  • 1. Design, synthesis, biological evaluation and in silico studies of novel pyrrolo[3,4-d]pyridazinone derivatives withpromising anti-inflammatory and antioxidant activity.
    Szczukowski Ł, Redzicka A, Wiatrak B, Krzyżak E, Marciniak A, Gębczak K, Gębarowski T, Świątek P.
    Bioorg Chem; 2020 Sep; 102():104035. PubMed ID: 32721780
    [Abstract] [Full Text] [Related]

  • 2. Design, Synthesis and Comprehensive Investigations of Pyrrolo[3,4-d]pyridazinone-Based 1,3,4-Oxadiazole as New Class of Selective COX-2 Inhibitors.
    Szczukowski Ł, Krzyżak E, Zborowska A, Zając P, Potyrak K, Peregrym K, Wiatrak B, Marciniak A, Świątek P.
    Int J Mol Sci; 2020 Dec 17; 21(24):. PubMed ID: 33348757
    [Abstract] [Full Text] [Related]

  • 3. New N-Substituted-1,2,4-triazole Derivatives of Pyrrolo[3,4-d]pyridazinone with Significant Anti-Inflammatory Activity-Design, Synthesis and Complementary In Vitro, Computational and Spectroscopic Studies.
    Szczukowski Ł, Krzyżak E, Wiatrak B, Jawień P, Marciniak A, Kotynia A, Świątek P.
    Int J Mol Sci; 2021 Oct 18; 22(20):. PubMed ID: 34681894
    [Abstract] [Full Text] [Related]

  • 4. In Vitro and In Silico Evaluation of New 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]pyridazinone as Promising Cyclooxygenase Inhibitors.
    Peregrym K, Szczukowski Ł, Wiatrak B, Potyrak K, Czyżnikowska Ż, Świątek P.
    Int J Mol Sci; 2021 Aug 24; 22(17):. PubMed ID: 34502040
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, Biological, Spectroscopic and Computational Investigations of Novel N-Acylhydrazone Derivatives of Pyrrolo[3,4-d]pyridazinone as Dual COX/LOX Inhibitors.
    Mikus J, Świątek P, Przybyła P, Krzyżak E, Marciniak A, Kotynia A, Redzicka A, Wiatrak B, Jawień P, Gębarowski T, Szczukowski Ł.
    Molecules; 2023 Jul 18; 28(14):. PubMed ID: 37513351
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of pyridazinone derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents.
    Ahmed EM, Kassab AE, El-Malah AA, Hassan MSA.
    Eur J Med Chem; 2019 Jun 01; 171():25-37. PubMed ID: 30904755
    [Abstract] [Full Text] [Related]

  • 7. Design and Synthesis of Novel 1,3,4-Oxadiazole and 1,2,4-Triazole Derivatives as Cyclooxygenase-2 Inhibitors with Anti-inflammatory and Antioxidant activity in LPS-stimulated RAW264.7 Macrophages.
    Hamoud MMS, Osman NA, Rezq S, A A Abd El-Wahab H, E A Hassan A, Abdel-Fattah HA, Romero DG, Ghanim AM.
    Bioorg Chem; 2022 Jul 01; 124():105808. PubMed ID: 35447409
    [Abstract] [Full Text] [Related]

  • 8. New pyridazine derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents; design, synthesis and biological evaluation.
    Ahmed EM, Hassan MSA, El-Malah AA, Kassab AE.
    Bioorg Chem; 2020 Jan 01; 95():103497. PubMed ID: 31838289
    [Abstract] [Full Text] [Related]

  • 9. Synthesis, Molecular Docking and Biological Evaluation of N-Substituted Indole Derivatives as Potential Anti-Inflammatory and Antioxidant Agents.
    Kumari A, Singh RK.
    Chem Biodivers; 2022 Sep 01; 19(9):e202200290. PubMed ID: 35818885
    [Abstract] [Full Text] [Related]

  • 10. COX-1/COX-2 inhibition activities and molecular docking study of newly designed and synthesized pyrrolo[3,4-c]pyrrole Mannich bases.
    Redzicka A, Szczukowski Ł, Kochel A, Wiatrak B, Gębczak K, Czyżnikowska Ż.
    Bioorg Med Chem; 2019 Sep 01; 27(17):3918-3928. PubMed ID: 31345747
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis, modeling studies and biological evaluation of thiazolidine derivatives containing pyrazole core as potential anti-diabetic PPAR-γ agonists and anti-inflammatory COX-2 selective inhibitors.
    Abdellatif KRA, Fadaly WAA, Kamel GM, Elshaier YAMM, El-Magd MA.
    Bioorg Chem; 2019 Feb 01; 82():86-99. PubMed ID: 30278282
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, molecular docking and biological evaluation of some newer 2-substituted-4-(benzo[d][1,3]dioxol-5-yl)-6-phenylpyridazin-3(2H)-ones as potential anti-inflammatory and analgesic agents.
    Singh J, Saini V, Kumar A, Bansal R.
    Bioorg Chem; 2017 Apr 01; 71():201-210. PubMed ID: 28236449
    [Abstract] [Full Text] [Related]

  • 13. Development of safe and antioxidant COX-2 inhibitors; Synthesis, molecular docking analysis and biological evaluation of novel pyrrolizine 5-carboxamides.
    K A Abdelall E, Elshemy HAH, Philoppes JN, Abdel-Fattah MM, El-Nahaas ES, Mahmoud RR.
    Bioorg Chem; 2024 Feb 01; 143():107098. PubMed ID: 38185010
    [Abstract] [Full Text] [Related]

  • 14. Discovery of novel pyrrolo-pyridine/pyrimidine derivatives bearing pyridazinone moiety as c-Met kinase inhibitors.
    Wang LX, Liu X, Xu S, Tang Q, Duan Y, Xiao Z, Zhi J, Jiang L, Zheng P, Zhu W.
    Eur J Med Chem; 2017 Dec 01; 141():538-551. PubMed ID: 29107421
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents.
    Özadalı K, Özkanlı F, Jain S, Rao PP, Velázquez-Martínez CA.
    Bioorg Med Chem; 2012 May 01; 20(9):2912-22. PubMed ID: 22475926
    [Abstract] [Full Text] [Related]

  • 16. Molecular Dynamics and Biological Evaluation of 2-chloro-7-cyclopentyl- 7H-pyrrolo[2,3-d]pyrimidine Derivatives Against Breast Cancer.
    Singaram K, Marimuthu D, Baskaran S, Chinaga SK, Shanmugarajan D, Vadivel T.
    Comb Chem High Throughput Screen; 2017 May 01; 20(8):703-712. PubMed ID: 28738766
    [Abstract] [Full Text] [Related]

  • 17. Anti-Inflammatory and Antioxidant Pyrrolo[3,4-d]pyridazinone Derivatives Interact with DNA and Bind to Plasma Proteins-Spectroscopic and In Silico Studies.
    Kotynia A, Krzyżak E, Żądło J, Witczak M, Szczukowski Ł, Mucha J, Świątek P, Marciniak A.
    Int J Mol Sci; 2024 Feb 01; 25(3):. PubMed ID: 38339061
    [Abstract] [Full Text] [Related]

  • 18. New 1,3,4-Oxadiazole Derivatives of Pyridothiazine-1,1-Dioxide with Anti-Inflammatory Activity.
    Glomb T, Wiatrak B, Gębczak K, Gębarowski T, Bodetko D, Czyżnikowska Ż, Świątek P.
    Int J Mol Sci; 2020 Nov 30; 21(23):. PubMed ID: 33266208
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, biological evaluation and docking study of a new series of di-substituted benzoxazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents.
    Kaur A, Pathak DP, Sharma V, Wakode S.
    Bioorg Med Chem; 2018 Feb 15; 26(4):891-902. PubMed ID: 29373271
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and molecular docking studies of new azomethine derivatives as promising anti-inflammatory agents.
    Desai SR, Desai VG, Pissurlenkar RR.
    Bioorg Chem; 2022 Mar 15; 120():105595. PubMed ID: 35074576
    [Abstract] [Full Text] [Related]

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