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Journal Abstract Search

291 related items for PubMed ID: 32747394

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  • 3. Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis.
    Dekkers JF, Berkers G, Kruisselbrink E, Vonk A, de Jonge HR, Janssens HM, Bronsveld I, van de Graaf EA, Nieuwenhuis EE, Houwen RH, Vleggaar FP, Escher JC, de Rijke YB, Majoor CJ, Heijerman HG, de Winter-de Groot KM, Clevers H, van der Ent CK, Beekman JM.
    Sci Transl Med; 2016 Jun 22; 8(344):344ra84. PubMed ID: 27334259
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  • 4. Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients.
    Boj SF, Vonk AM, Statia M, Su J, Vries RR, Beekman JM, Clevers H.
    J Vis Exp; 2017 Feb 11; (120):. PubMed ID: 28287550
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  • 9. Forskolin-induced swelling of intestinal organoids correlates with disease severity in adults with cystic fibrosis and homozygous F508del mutations.
    de Winter-de Groot KM, Berkers G, Marck-van der Wilt REP, van der Meer R, Vonk A, Dekkers JF, Geerdink M, Michel S, Kruisselbrink E, Vries R, Clevers H, Vleggaar FP, Elias SG, Heijerman HGM, van der Ent CK, Beekman JM.
    J Cyst Fibros; 2020 Jul 11; 19(4):614-619. PubMed ID: 31735562
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  • 11. FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes.
    de Poel E, Spelier S, Hagemeijer MC, van Mourik P, Suen SWF, Vonk AM, Brunsveld JE, Ithakisiou GN, Kruisselbrink E, Oppelaar H, Berkers G, de Winter de Groot KM, Heida-Michel S, Jans SR, van Panhuis H, Bakker M, van der Meer R, Roukema J, Dompeling E, Weersink EJM, Koppelman GH, Blaazer AR, Muijlwijk-Koezen JE, van der Ent CK, Beekman JM.
    J Cyst Fibros; 2023 May 11; 22(3):548-559. PubMed ID: 37147251
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  • 12. Molecular Dynamics and Theratyping in Airway and Gut Organoids Reveal R352Q-CFTR Conductance Defect.
    Wong SL, Awatade NT, Astore MA, Allan KM, Carnell MJ, Slapetova I, Chen PC, Setiadi J, Pandzic E, Fawcett LK, Widger JR, Whan RM, Griffith R, Ooi CY, Kuyucak S, Jaffe A, Waters SA.
    Am J Respir Cell Mol Biol; 2022 Jul 11; 67(1):99-111. PubMed ID: 35471184
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  • 13. R560S: A class II CFTR mutation that is not rescued by current modulators.
    Awatade NT, Ramalho S, Silva IAL, Felício V, Botelho HM, de Poel E, Vonk A, Beekman JM, Farinha CM, Amaral MD.
    J Cyst Fibros; 2019 Mar 11; 18(2):182-189. PubMed ID: 30030066
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  • 16. Effects of Lumacaftor-Ivacaftor Therapy on Cystic Fibrosis Transmembrane Conductance Regulator Function in Phe508del Homozygous Patients with Cystic Fibrosis.
    Graeber SY, Dopfer C, Naehrlich L, Gyulumyan L, Scheuermann H, Hirtz S, Wege S, Mairbäurl H, Dorda M, Hyde R, Bagheri-Hanson A, Rueckes-Nilges C, Fischer S, Mall MA, Tümmler B.
    Am J Respir Crit Care Med; 2018 Jun 01; 197(11):1433-1442. PubMed ID: 29327948
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  • 18. Potentiator synergy in rectal organoids carrying S1251N, G551D, or F508del CFTR mutations.
    Dekkers JF, Van Mourik P, Vonk AM, Kruisselbrink E, Berkers G, de Winter-de Groot KM, Janssens HM, Bronsveld I, van der Ent CK, de Jonge HR, Beekman JM.
    J Cyst Fibros; 2016 Sep 01; 15(5):568-78. PubMed ID: 27160424
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  • 19. Forskolin induced swelling (FIS) assay in intestinal organoids to guide eligibility for compassionate use treatment in a CF patient with a rare genotype.
    Aalbers BL, Brunsveld JE, van der Ent CK, van den Eijnden JC, Beekman JM, Heijerman HGM.
    J Cyst Fibros; 2022 Mar 01; 21(2):254-257. PubMed ID: 35110005
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