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Journal Abstract Search

500 related items for PubMed ID: 32768647

  • 1. Anti-proliferative potential of triphenyl substituted pyrimidines against MDA-MB-231, HCT-116 and HT-29 cancer cell lines.
    Ranjan Dwivedi A, Kumar V, Kaur H, Kumar N, Prakash Yadav R, Poduri R, Baranwal S, Kumar V.
    Bioorg Med Chem Lett; 2020 Oct 15; 30(20):127468. PubMed ID: 32768647
    [Abstract] [Full Text] [Related]

  • 2. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):640-658. PubMed ID: 33588683
    [Abstract] [Full Text] [Related]

  • 3. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 15; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 4. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
    Jadala C, Sathish M, Anchi P, Tokala R, Lakshmi UJ, Reddy VG, Shankaraiah N, Godugu C, Kamal A.
    ChemMedChem; 2019 Dec 17; 14(24):2052-2060. PubMed ID: 31674147
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of novel indole-pyrimidine hybrids bearing morpholine and thiomorpholine moieties.
    Diao PC, Li Q, Hu MJ, Ma YF, You WW, Hong KH, Zhao PL.
    Eur J Med Chem; 2017 Jul 07; 134():110-118. PubMed ID: 28410492
    [Abstract] [Full Text] [Related]

  • 6. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
    Yang F, Yu LZ, Diao PC, Jian XE, Zhou MF, Jiang CS, You WW, Ma WF, Zhao PL.
    Bioorg Chem; 2019 Nov 07; 92():103260. PubMed ID: 31525523
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
    Liu R, Zhang S, Huang M, Guo Z, Li L, Li M, Wu L, Guan Q, Zhang W.
    Bioorg Chem; 2021 Oct 01; 115():105220. PubMed ID: 34352709
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G, Wang Y, Li L, Ren Y, Deng X, Liu J, Wang W, Luo M, Liu S, Chen J.
    Eur J Med Chem; 2020 Sep 15; 202():112519. PubMed ID: 32650183
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS, Tabeshpour J, Mirzaei S, Golmakaniyoon S, Tayarani-Najaran Z, Ghasemi A, Ghodsi R.
    Arch Pharm (Weinheim); 2019 Jun 15; 352(6):e1800307. PubMed ID: 31012156
    [Abstract] [Full Text] [Related]

  • 11. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
    Farghaly AM, AboulWafa OM, Baghdadi HH, Abd El Razik HA, Sedra SMY, Shamaa MM.
    Bioorg Chem; 2021 Oct 15; 115():105208. PubMed ID: 34365057
    [Abstract] [Full Text] [Related]

  • 12. Combretastatin linked 1,3,4-oxadiazole conjugates as a Potent Tubulin Polymerization inhibitors.
    Kamal A, Srikanth PS, Vishnuvardhan MV, Kumar GB, Suresh Babu K, Hussaini SM, Kapure JS, Alarifi A.
    Bioorg Chem; 2016 Apr 15; 65():126-36. PubMed ID: 26943479
    [Abstract] [Full Text] [Related]

  • 13. Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding site.
    Wang G, Liu W, Gong Z, Huang Y, Li Y, Peng Z.
    J Enzyme Inhib Med Chem; 2020 Dec 15; 35(1):139-144. PubMed ID: 31724435
    [Abstract] [Full Text] [Related]

  • 14. Design, Synthesis and Molecular Docking Studies of Novel Indole-Pyrimidine Hybrids as Tubulin Polymerization Inhibitors.
    Hu MJ, Zhang B, Yang HK, Liu Y, Chen YR, Ma TZ, Lu L, You WW, Zhao PL.
    Chem Biol Drug Des; 2015 Dec 15; 86(6):1491-500. PubMed ID: 26177395
    [Abstract] [Full Text] [Related]

  • 15. Design and synthesis of novel tetrabromophthalimide derivatives as potential tubulin inhibitors endowed with apoptotic induction for cancer treatment.
    Abdel-Motaal M, Aldakhili DA, Abo Elmaaty A, Sharaky M, Mourad MAE, Alzahrani AYA, Mohamed NA, Al-Karmalawy AA.
    Drug Dev Res; 2024 Jun 15; 85(4):e22197. PubMed ID: 38751223
    [Abstract] [Full Text] [Related]

  • 16. Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
    Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):802-818. PubMed ID: 33730937
    [Abstract] [Full Text] [Related]

  • 17. Tubulin inhibitors: Discovery of a new scaffold targeting extra-binding residues within the colchicine site through anchoring substituents properly adapted to their pocket by a semi-flexible linker.
    Maklad RM, AbdelHafez EMN, Abdelhamid D, Aly OM.
    Bioorg Chem; 2020 Jun 15; 99():103767. PubMed ID: 32325332
    [Abstract] [Full Text] [Related]

  • 18. Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors.
    Sana S, Tokala R, Bajaj DM, Nagesh N, Bokara KK, Kiranmai G, Lakshmi UJ, Vadlamani S, Talla V, Shankaraiah N.
    Bioorg Chem; 2019 Dec 15; 93():103317. PubMed ID: 31586714
    [Abstract] [Full Text] [Related]

  • 19. 2-Anilinopyrimidine derivatives: Design, synthesis, in vitro anti-proliferative activity, EGFR and ARO inhibitory activity, cell cycle analysis and molecular docking study.
    AboulWafa OM, Daabees HMG, Badawi WA.
    Bioorg Chem; 2020 Jun 15; 99():103798. PubMed ID: 32247112
    [Abstract] [Full Text] [Related]

  • 20. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
    Yang F, He CP, Diao PC, Hong KH, Rao JJ, Zhao PL.
    Bioorg Med Chem Lett; 2019 Jan 01; 29(1):22-27. PubMed ID: 30448234
    [Abstract] [Full Text] [Related]

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