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241 related items for PubMed ID: 32776498

  • 1. Effects of RAGE inhibition on the progression of the disease in hSOD1G93A ALS mice.
    Liu L, Killoy KM, Vargas MR, Yamamoto Y, Pehar M.
    Pharmacol Res Perspect; 2020 Aug; 8(4):e00636. PubMed ID: 32776498
    [Abstract] [Full Text] [Related]

  • 2. Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner.
    MacLean M, Juranek J, Cuddapah S, López-Díez R, Ruiz HH, Hu J, Frye L, Li H, Gugger PF, Schmidt AM.
    J Neuroinflammation; 2021 Jun 15; 18(1):139. PubMed ID: 34130712
    [Abstract] [Full Text] [Related]

  • 3. Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis.
    Lee JD, McDonald TS, Fung JNT, Woodruff TM.
    Mol Neurobiol; 2020 Oct 15; 57(10):4143-4155. PubMed ID: 32676989
    [Abstract] [Full Text] [Related]

  • 4. Toll-Like Receptor-4 Inhibitor TAK-242 Attenuates Motor Dysfunction and Spinal Cord Pathology in an Amyotrophic Lateral Sclerosis Mouse Model.
    Fellner A, Barhum Y, Angel A, Perets N, Steiner I, Offen D, Lev N.
    Int J Mol Sci; 2017 Aug 01; 18(8):. PubMed ID: 28763002
    [Abstract] [Full Text] [Related]

  • 5. Desloratadine alleviates ALS-like pathology in hSOD1G93A mice via targeting 5HTR2A on activated spinal astrocytes.
    Lu J, He AX, Jin ZY, Zhang M, Li ZX, Zhou F, Ma L, Jin HM, Wang JY, Shen X.
    Acta Pharmacol Sin; 2024 May 01; 45(5):926-944. PubMed ID: 38286832
    [Abstract] [Full Text] [Related]

  • 6. Nuclear Localization of Human SOD1 in Motor Neurons in Mouse Model and Patient Amyotrophic Lateral Sclerosis: Possible Links to Cholinergic Phenotype, NADPH Oxidase, Oxidative Stress, and DNA Damage.
    Martin LJ, Koh SJ, Price A, Park D, Kim BW.
    Int J Mol Sci; 2024 Aug 22; 25(16):. PubMed ID: 39201793
    [Abstract] [Full Text] [Related]

  • 7. Novel insights into RAGE signaling pathways during the progression of amyotrophic lateral sclerosis in RAGE-deficient SOD1 G93A mice.
    Nowicka N, Zglejc-Waszak K, Juranek J, Korytko A, Wąsowicz K, Chmielewska-Krzesińska M, Wojtkiewicz J.
    PLoS One; 2024 Aug 22; 19(3):e0299567. PubMed ID: 38457412
    [Abstract] [Full Text] [Related]

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  • 9. The Involvement of RAGE and Its Ligands during Progression of ALS in SOD1 G93A Transgenic Mice.
    Nowicka N, Szymańska K, Juranek J, Zglejc-Waszak K, Korytko A, Załęcki M, Chmielewska-Krzesińska M, Wąsowicz K, Wojtkiewicz J.
    Int J Mol Sci; 2022 Feb 16; 23(4):. PubMed ID: 35216298
    [Abstract] [Full Text] [Related]

  • 10. Calpastatin inhibits motor neuron death and increases survival of hSOD1(G93A) mice.
    Rao MV, Campbell J, Palaniappan A, Kumar A, Nixon RA.
    J Neurochem; 2016 Apr 16; 137(2):253-65. PubMed ID: 26756888
    [Abstract] [Full Text] [Related]

  • 11. Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1 G93A mouse model of amyotrophic lateral sclerosis.
    Lee JY, Lee JD, Phipps S, Noakes PG, Woodruff TM.
    J Neuroinflammation; 2015 May 13; 12():90. PubMed ID: 25962427
    [Abstract] [Full Text] [Related]

  • 12. Decreased glutathione levels cause overt motor neuron degeneration in hSOD1WT over-expressing mice.
    Killoy KM, Harlan BA, Pehar M, Helke KL, Johnson JA, Vargas MR.
    Exp Neurol; 2018 Apr 13; 302():129-135. PubMed ID: 29307609
    [Abstract] [Full Text] [Related]

  • 13. Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis.
    Lee JD, Kumar V, Fung JN, Ruitenberg MJ, Noakes PG, Woodruff TM.
    Br J Pharmacol; 2017 Apr 13; 174(8):689-699. PubMed ID: 28128456
    [Abstract] [Full Text] [Related]

  • 14. Nuclear localization of human SOD1 and mutant SOD1-specific disruption of survival motor neuron protein complex in transgenic amyotrophic lateral sclerosis mice.
    Gertz B, Wong M, Martin LJ.
    J Neuropathol Exp Neurol; 2012 Feb 13; 71(2):162-77. PubMed ID: 22249462
    [Abstract] [Full Text] [Related]

  • 15. The alteration of serine transporter activity in a cell line model of amyotrophic lateral sclerosis (ALS).
    Lee NY, Kim Y, Ryu H, Kang YS.
    Biochem Biophys Res Commun; 2017 Jan 29; 483(1):135-141. PubMed ID: 28043791
    [Abstract] [Full Text] [Related]

  • 16. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D, Haasdijk ED, Grashorn JA, Hawkins R, van Duijn W, Verspaget HW, London J, Holstege JC.
    Neurobiol Dis; 2000 Dec 29; 7(6 Pt B):623-43. PubMed ID: 11114261
    [Abstract] [Full Text] [Related]

  • 17. GLT1 overexpression in SOD1(G93A) mouse cervical spinal cord does not preserve diaphragm function or extend disease.
    Li K, Hala TJ, Seetharam S, Poulsen DJ, Wright MC, Lepore AC.
    Neurobiol Dis; 2015 Jun 29; 78():12-23. PubMed ID: 25818008
    [Abstract] [Full Text] [Related]

  • 18. Transient recovery in a rat model of familial amyotrophic lateral sclerosis after transplantation of motor neurons derived from mouse embryonic stem cells.
    López-González R, Kunckles P, Velasco I.
    Cell Transplant; 2009 Jun 29; 18(10):1171-81. PubMed ID: 19660174
    [Abstract] [Full Text] [Related]

  • 19. TDP-43 modification in the hSOD1(G93A) amyotrophic lateral sclerosis mouse model.
    Cai M, Lee KW, Choi SM, Yang EJ.
    Neurol Res; 2015 Mar 29; 37(3):253-62. PubMed ID: 25213598
    [Abstract] [Full Text] [Related]

  • 20. Complement C5a-C5aR1 signalling drives skeletal muscle macrophage recruitment in the hSOD1G93A mouse model of amyotrophic lateral sclerosis.
    Wang HA, Lee JD, Lee KM, Woodruff TM, Noakes PG.
    Skelet Muscle; 2017 Jun 01; 7(1):10. PubMed ID: 28571586
    [Abstract] [Full Text] [Related]

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