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162 related items for PubMed ID: 32783298

  • 1. A Novel Prodrug of a nNOS Inhibitor with Improved Pharmacokinetic Potential.
    Maccallini C, Marinelli L, Indorf P, Cacciatore I, Fantacuzzi M, Clement B, Di Stefano A, Amoroso R.
    ChemMedChem; 2020 Nov 18; 15(22):2157-2163. PubMed ID: 32783298
    [Abstract] [Full Text] [Related]

  • 2. Synthesis, bioevaluation and docking studies of new imidamide derivatives as nitric oxide synthase inhibitors.
    Arias F, Franco-Montalban F, Romero M, Carrión MD, Camacho ME.
    Bioorg Med Chem; 2021 Aug 15; 44():116294. PubMed ID: 34218000
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  • 4. N-Phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: structure-activity studies and demonstration of in vivo activity.
    Collins JL, Shearer BG, Oplinger JA, Lee S, Garvey EP, Salter M, Duffy C, Burnette TC, Furfine ES.
    J Med Chem; 1998 Jul 16; 41(15):2858-71. PubMed ID: 9667974
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  • 5. Orally active factor Xa inhibitors: investigation of a novel series of 3-amidinophenylsulfonamide derivatives using an amidoxime prodrug strategy.
    Uchida M, Okazaki K, Mukaiyama H, Isawa H, Kobayashi H, Shiohara H, Muranaka H, Kai Y, Kikuchi N, Takeuchi H, Yokoyama K, Tsuji E, Ozawa T, Hoyano Y, Koizumi T, Misawa K, Hara K, Nakano S, Murakami Y, Okuno H.
    Bioorg Med Chem Lett; 2008 Aug 15; 18(16):4682-7. PubMed ID: 18667303
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  • 6. Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker.
    Wang HY, Qin Y, Li H, Roman LJ, Martásek P, Poulos TL, Silverman RB.
    J Med Chem; 2016 May 26; 59(10):4913-25. PubMed ID: 27050842
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  • 8. Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor.
    Young RJ, Alderton W, Angell AD, Beswick PJ, Brown D, Chambers CL, Crowe MC, Dawson J, Hamlett CC, Hodgson ST, Kleanthous S, Knowles RG, Russell LJ, Stocker R, Woolven JM.
    Bioorg Med Chem Lett; 2011 May 15; 21(10):3037-40. PubMed ID: 21482467
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  • 10. Potent and selective double-headed thiophene-2-carboximidamide inhibitors of neuronal nitric oxide synthase for the treatment of melanoma.
    Huang H, Li H, Yang S, Chreifi G, Martásek P, Roman LJ, Meyskens FL, Poulos TL, Silverman RB.
    J Med Chem; 2014 Feb 13; 57(3):686-700. PubMed ID: 24447275
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  • 13. Selective inhibition of inducible nitric oxide synthase by derivatives of acetamidine.
    Maccallini C, Patruno A, Ammazzalorso A, De Filippis B, Fantacuzzi M, Franceschelli S, Giampietro L, Masella S, Tricca ML, Amoroso R.
    Med Chem; 2012 Nov 13; 8(6):991-5. PubMed ID: 22741778
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  • 14. 2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
    Vasu D, Li H, Hardy CD, Poulos TL, Silverman RB.
    Bioorg Med Chem; 2022 Sep 01; 69():116878. PubMed ID: 35772285
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  • 15. Computational development of selective nNOS inhibitors: binding modes and pharmacokinetic considerations.
    Curtin AM, Kinsella GK, Stephens JC.
    Curr Med Chem; 2015 Sep 01; 22(21):2558-79. PubMed ID: 25921643
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  • 16. A cellular model for screening neuronal nitric oxide synthase inhibitors.
    Fang J, Silverman RB.
    Anal Biochem; 2009 Jul 01; 390(1):74-8. PubMed ID: 19362065
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  • 17. Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase.
    Hah JM, Martásek P, Roman LJ, Silverman RB.
    J Med Chem; 2003 Apr 24; 46(9):1661-9. PubMed ID: 12699384
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  • 18. Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.
    Cinelli MA, Li H, Pensa AV, Kang S, Roman LJ, Martásek P, Poulos TL, Silverman RB.
    J Med Chem; 2015 Nov 12; 58(21):8694-712. PubMed ID: 26469213
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  • 19. Recent advances toward improving the bioavailability of neuronal nitric oxide synthase inhibitors.
    Huang H, Silverman RB.
    Curr Top Med Chem; 2013 Nov 12; 13(7):803-12. PubMed ID: 23578024
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  • 20. Inactivation Mechanism of Neuronal Nitric Oxide Synthase by (S)-2-Amino-5-(2-(methylthio)acetimidamido)pentanoic Acid: Chemical Conversion of the Inactivator in the Active Site.
    Yan L, Wang Y, Zhang S, Li X, Wei J, Wang Z, Liu Y.
    Inorg Chem; 2021 Jul 05; 60(13):9345-9358. PubMed ID: 34137256
    [Abstract] [Full Text] [Related]

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