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Journal Abstract Search

173 related items for PubMed ID: 32786399

  • 1. Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center.
    Sharma AN, Grandinetti L, Johnson ER, St Maurice M, Bearne SL.
    Biochemistry; 2020 Aug 25; 59(33):3026-3037. PubMed ID: 32786399
    [Abstract] [Full Text] [Related]

  • 2. An additional role for the Brønsted acid-base catalysts of mandelate racemase in transition state stabilization.
    Nagar M, Bearne SL.
    Biochemistry; 2015 Nov 10; 54(44):6743-52. PubMed ID: 26480244
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  • 4. Mechanism of the reaction catalyzed by mandelate racemase: structure and mechanistic properties of the K166R mutant.
    Kallarakal AT, Mitra B, Kozarich JW, Gerlt JA, Clifton JG, Petsko GA, Kenyon GL.
    Biochemistry; 1995 Mar 07; 34(9):2788-97. PubMed ID: 7893690
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  • 5. A Phenylboronic Acid-Based Transition State Analogue Yields Nanomolar Inhibition of Mandelate Racemase.
    Kuehm OP, Hayden JA, Bearne SL.
    Biochemistry; 2023 Jun 20; 62(12):1929-1942. PubMed ID: 37285384
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  • 7. Altering the Y137-K164-K166 triad of mandelate racemase and its effect on the observed pKa of the Brønsted base catalysts.
    Fetter CM, Morrison ZA, Nagar M, Douglas CD, Bearne SL.
    Arch Biochem Biophys; 2019 May 15; 666():116-126. PubMed ID: 30935886
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  • 10. Mechanism of the reaction catalyzed by mandelate racemase: importance of electrophilic catalysis by glutamic acid 317.
    Mitra B, Kallarakal AT, Kozarich JW, Gerlt JA, Clifton JG, Petsko GA, Kenyon GL.
    Biochemistry; 1995 Mar 07; 34(9):2777-87. PubMed ID: 7893689
    [Abstract] [Full Text] [Related]

  • 11. Altering the binding determinant on the interdigitating loop of mandelate racemase shifts specificity towards that of d-tartrate dehydratase.
    Nagar M, Hayden JA, Sagey E, Worthen G, Park M, Sharma AN, Fetter CM, Kuehm OP, Bearne SL.
    Arch Biochem Biophys; 2022 Mar 30; 718():109119. PubMed ID: 35016855
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  • 12. Mechanism of the reaction catalyzed by mandelate racemase. 3. Asymmetry in reactions catalyzed by the H297N mutant.
    Landro JA, Kallarakal AT, Ransom SC, Gerlt JA, Kozarich JW, Neidhart DJ, Kenyon GL.
    Biochemistry; 1991 Sep 24; 30(38):9274-81. PubMed ID: 1909893
    [Abstract] [Full Text] [Related]

  • 13. Perturbing the hydrophobic pocket of mandelate racemase to probe phenyl motion during catalysis.
    Siddiqi F, Bourque JR, Jiang H, Gardner M, St Maurice M, Blouin C, Bearne SL.
    Biochemistry; 2005 Jun 28; 44(25):9013-21. PubMed ID: 15966725
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  • 14. Hydrophobic nature of the active site of mandelate racemase.
    St Maurice M, Bearne SL.
    Biochemistry; 2004 Mar 09; 43(9):2524-32. PubMed ID: 14992589
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  • 15. Structure of mandelate racemase with bound intermediate analogues benzohydroxamate and cupferron.
    Lietzan AD, Nagar M, Pellmann EA, Bourque JR, Bearne SL, St Maurice M.
    Biochemistry; 2012 Feb 14; 51(6):1160-70. PubMed ID: 22264153
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  • 16. Virtual screening of mandelate racemase mutants with enhanced activity based on binding energy in the transition state.
    Gu J, Liu M, Guo F, Xie W, Lu W, Ye L, Chen Z, Yuan S, Yu H.
    Enzyme Microb Technol; 2014 Feb 05; 55():121-7. PubMed ID: 24411454
    [Abstract] [Full Text] [Related]

  • 17. A platform for chemical modification of mandelate racemase: characterization of the C92S/C264S and γ-thialysine 166 variants.
    Nagar M, Kumar H, Bearne SL.
    Protein Eng Des Sel; 2018 Apr 01; 31(4):135-145. PubMed ID: 29850884
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  • 19. Slow-Onset, Potent Inhibition of Mandelate Racemase by 2-Formylphenylboronic Acid. An Unexpected Adduct Clasps the Catalytic Machinery.
    Douglas CD, Grandinetti L, Easton NM, Kuehm OP, Hayden JA, Hamilton MC, St Maurice M, Bearne SL.
    Biochemistry; 2021 Aug 02. PubMed ID: 34339165
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  • 20. Inactivation of Mandelate Racemase by 3-Hydroxypyruvate Reveals a Potential Mechanistic Link between Enzyme Superfamilies.
    Nagar M, Wyatt BN, St Maurice M, Bearne SL.
    Biochemistry; 2015 May 05; 54(17):2747-57. PubMed ID: 25844917
    [Abstract] [Full Text] [Related]

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