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147 related items for PubMed ID: 32840370
1. Affinity Crystallography Reveals Binding of Pomegranate Juice Anthocyanins at the Inhibitor Site of Glycogen Phosphorylase: The Contribution of a Sugar Moiety to Potency and Its Implications to the Binding Mode. Drakou CE, Gardeli C, Tsialtas I, Alexopoulos S, Mallouchos A, Koulas SM, Tsagkarakou AS, Asimakopoulos D, Leonidas DD, Psarra AG, Skamnaki VT. J Agric Food Chem; 2020 Sep 16; 68(37):10191-10199. PubMed ID: 32840370 [Abstract] [Full Text] [Related]
2. Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase. Stravodimos GA, Kantsadi AL, Apostolou A, Kyriakis E, Kafaski-Kanelli VN, Solovou T, Gatzona P, Liggri PGV, Theofanous S, Gorgogietas VA, Kissa A, Psachoula C, Lemonakis A, Chatzileontiadou DSM, Psarra AG, Skamnaki VT, Haroutounian SA, Leonidas DD. Curr Drug Discov Technol; 2018 Sep 16; 15(1):41-53. PubMed ID: 28625148 [Abstract] [Full Text] [Related]
3. Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol. Tsitsanou KE, Hayes JM, Keramioti M, Mamais M, Oikonomakos NG, Kato A, Leonidas DD, Zographos SE. Food Chem Toxicol; 2013 Nov 16; 61():14-27. PubMed ID: 23279842 [Abstract] [Full Text] [Related]
4. Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors. Chetter BA, Kyriakis E, Barr D, Karra AG, Katsidou E, Koulas SM, Skamnaki VT, Snape TJ, Psarra AG, Leonidas DD, Hayes JM. Bioorg Chem; 2020 Sep 16; 102():104003. PubMed ID: 32771768 [Abstract] [Full Text] [Related]
6. High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-β-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors. Fischer T, Koulas SM, Tsagkarakou AS, Kyriakis E, Stravodimos GA, Skamnaki VT, Liggri PGV, Zographos SE, Riedl R, Leonidas DD. Molecules; 2019 Apr 03; 24(7):. PubMed ID: 30987252 [Abstract] [Full Text] [Related]
7. Glycogen phosphorylase as a molecular target for type 2 diabetes therapy. Oikonomakos NG. Curr Protein Pept Sci; 2002 Dec 03; 3(6):561-86. PubMed ID: 12470212 [Abstract] [Full Text] [Related]
8. Pomegranate juice as a functional food: a comprehensive review of its polyphenols, therapeutic merits, and recent patents. Fahmy H, Hegazi N, El-Shamy S, Farag MA. Food Funct; 2020 Jul 01; 11(7):5768-5781. PubMed ID: 32608443 [Abstract] [Full Text] [Related]
9. Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site. Kristiansen M, Andersen B, Iversen LF, Westergaard N. J Med Chem; 2004 Jul 01; 47(14):3537-45. PubMed ID: 15214781 [Abstract] [Full Text] [Related]
10. Biochemical and biological assessment of the inhibitory potency of extracts from vinification byproducts of Vitis vinifera extracts against glycogen phosphorylase. Kantsadi AL, Apostolou A, Theofanous S, Stravodimos GA, Kyriakis E, Gorgogietas VA, Chatzileontiadou DS, Pegiou K, Skamnaki VT, Stagos D, Kouretas D, Psarra AM, Haroutounian SA, Leonidas DD. Food Chem Toxicol; 2014 May 01; 67():35-43. PubMed ID: 24556570 [Abstract] [Full Text] [Related]
11. Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding. Alexacou KM, Hayes JM, Tiraidis C, Zographos SE, Leonidas DD, Chrysina ED, Archontis G, Oikonomakos NG, Paul JV, Varghese B, Loganathan D. Proteins; 2008 May 15; 71(3):1307-23. PubMed ID: 18041758 [Abstract] [Full Text] [Related]
12. Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition. Oikonomakos NG, Tiraidis C, Leonidas DD, Zographos SE, Kristiansen M, Jessen CU, Nørskov-Lauritsen L, Agius L. J Med Chem; 2006 Sep 21; 49(19):5687-701. PubMed ID: 16970395 [Abstract] [Full Text] [Related]
13. A New Potent Inhibitor of Glycogen Phosphorylase Reveals the Basicity of the Catalytic Site. Mamais M, Degli Esposti A, Kouloumoundra V, Gustavsson T, Monti F, Venturini A, Chrysina ED, Markovitsi D, Gimisis T. Chemistry; 2017 Jul 03; 23(37):8800-8805. PubMed ID: 28493496 [Abstract] [Full Text] [Related]
14. Glycogen phosphorylase inhibitors: a free energy perturbation analysis of glucopyranose spirohydantoin analogues. Archontis G, Watson KA, Xie Q, Andreou G, Chrysina ED, Zographos SE, Oikonomakos NG, Karplus M. Proteins; 2005 Dec 01; 61(4):984-98. PubMed ID: 16245298 [Abstract] [Full Text] [Related]
15. Halogen-substituted (C-β-D-glucopyranosyl)-hydroquinone regioisomers: synthesis, enzymatic evaluation and their binding to glycogen phosphorylase. Alexacou KM, Zhang YZ, Praly JP, Zographos SE, Chrysina ED, Oikonomakos NG, Leonidas DD. Bioorg Med Chem; 2011 Sep 01; 19(17):5125-36. PubMed ID: 21821421 [Abstract] [Full Text] [Related]
16. Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase. Kantsadi AL, Bokor É, Kun S, Stravodimos GA, Chatzileontiadou DSM, Leonidas DD, Juhász-Tóth É, Szakács A, Batta G, Docsa T, Gergely P, Somsák L. Eur J Med Chem; 2016 Nov 10; 123():737-745. PubMed ID: 27522507 [Abstract] [Full Text] [Related]
17. Clarification of pomegranate and strawberry juices: Effects of various clarification agents on turbidity, anthocyanins, colour, phenolics and antioxidant activity. Orhan Dereli B, Türkyılmaz M, Özkan M. Food Chem; 2023 Jul 01; 413():135672. PubMed ID: 36804743 [Abstract] [Full Text] [Related]
18. [Pomegranate juice nutritional profile]. Khomich LM, Perova IB, Eller KI. Vopr Pitan; 2019 Jul 01; 88(5):80-92. PubMed ID: 31710791 [Abstract] [Full Text] [Related]
19. Probing the β-pocket of the active site of human liver glycogen phosphorylase with 3-(C-β-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors. Kyriakis E, Solovou TGA, Kun S, Czifrák K, Szőcs B, Juhász L, Bokor É, Stravodimos GA, Kantsadi AL, Chatzileontiadou DSM, Skamnaki VT, Somsák L, Leonidas DD. Bioorg Chem; 2018 Apr 01; 77():485-493. PubMed ID: 29454281 [Abstract] [Full Text] [Related]
20. Pomegranate Fruit and Juice (cv. Mollar), Rich in Ellagitannins and Anthocyanins, Also Provide a Significant Content of a Wide Range of Proanthocyanidins. Díaz-Mula HM, Tomás-Barberán FA, García-Villalba R. J Agric Food Chem; 2019 Aug 21; 67(33):9160-9167. PubMed ID: 30768267 [Abstract] [Full Text] [Related] Page: [Next] [New Search]