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Journal Abstract Search

434 related items for PubMed ID: 32848361

  • 1. Novel HDAC/Tubulin Dual Inhibitor: Design, Synthesis and Docking Studies of α-Phthalimido-Chalcone Hybrids as Potential Anticancer Agents with Apoptosis-Inducing Activity.
    Mourad AAE, Mourad MAE, Jones PG.
    Drug Des Devel Ther; 2020; 14():3111-3130. PubMed ID: 32848361
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors.
    Rahimzadeh Oskuei S, Mirzaei S, Reza Jafari-Nik M, Hadizadeh F, Eisvand F, Mosaffa F, Ghodsi R.
    Bioorg Chem; 2021 Jul; 112():104904. PubMed ID: 33933802
    [Abstract] [Full Text] [Related]

  • 3. Anti-tumor activity evaluation of novel tubulin and HDAC dual-targeting inhibitors.
    Wang B, Chen X, Gao J, Su L, Zhang L, Xu H, Luan Y.
    Bioorg Med Chem Lett; 2019 Sep 15; 29(18):2638-2645. PubMed ID: 31400938
    [Abstract] [Full Text] [Related]

  • 4. Discovery of novel tubulin/HDAC dual-targeting inhibitors with strong antitumor and antiangiogenic potency.
    Wang Y, Sun M, Wang Y, Qin J, Zhang Y, Pang Y, Yao Y, Yang H, Duan Y.
    Eur J Med Chem; 2021 Dec 05; 225():113790. PubMed ID: 34454126
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  • 5. Design, synthesis, biological evaluation and molecular docking studies of new chalcone derivatives containing diaryl ether moiety as potential anticancer agents and tubulin polymerization inhibitors.
    Wang G, Liu W, Gong Z, Huang Y, Li Y, Peng Z.
    Bioorg Chem; 2020 Jan 05; 95():103565. PubMed ID: 31927336
    [Abstract] [Full Text] [Related]

  • 6. Design and synthesis of novel imidazole-chalcone derivatives as microtubule protein polymerization inhibitors to treat cervical cancer and reverse cisplatin resistance.
    Liu Z, Yang Z, Ablise M.
    Bioorg Chem; 2024 Jun 05; 147():107310. PubMed ID: 38583249
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis and biological evaluation of colchicine derivatives as novel tubulin and histone deacetylase dual inhibitors.
    Zhang X, Kong Y, Zhang J, Su M, Zhou Y, Zang Y, Li J, Chen Y, Fang Y, Zhang X, Lu W.
    Eur J Med Chem; 2015 May 05; 95():127-35. PubMed ID: 25805446
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 9. The discovery of colchicine-SAHA hybrids as a new class of antitumor agents.
    Zhang X, Zhang J, Tong L, Luo Y, Su M, Zang Y, Li J, Lu W, Chen Y.
    Bioorg Med Chem; 2013 Jun 01; 21(11):3240-4. PubMed ID: 23602523
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 Jun 01; 21(8):1047-1055. PubMed ID: 32981511
    [Abstract] [Full Text] [Related]

  • 11. Spirohydantoins and 1,2,4-triazole-3-carboxamide derivatives as inhibitors of histone deacetylase: Design, synthesis, and biological evaluation.
    Aboeldahab AMA, Beshr EAM, Shoman ME, Rabea SM, Aly OM.
    Eur J Med Chem; 2018 Feb 25; 146():79-92. PubMed ID: 29396364
    [Abstract] [Full Text] [Related]

  • 12. Utilization of cyanopyridine in design and synthesis of first-in-class anticancer dual acting PIM-1 kinase/HDAC inhibitors.
    Bass AKA, Nageeb EM, El-Zoghbi MS, Mohamed MFA, Badr M, Abuo-Rahma GEA.
    Bioorg Chem; 2022 Feb 25; 119():105564. PubMed ID: 34959179
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS, Tabeshpour J, Mirzaei S, Golmakaniyoon S, Tayarani-Najaran Z, Ghasemi A, Ghodsi R.
    Arch Pharm (Weinheim); 2019 Jun 25; 352(6):e1800307. PubMed ID: 31012156
    [Abstract] [Full Text] [Related]

  • 14. 1,3,4-oxadiazole-2-thione Derivatives; Novel Approach for Anticancer and Tubulin Polymerization Inhibitory Activities.
    Abdel-Aziz M, Metwally KA, Gamal-Eldeen AM, Aly OM.
    Anticancer Agents Med Chem; 2015 Jun 25; 16(2):269-77. PubMed ID: 26343141
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and biological evaluation of novel 2-aminobenzamides containing dithiocarbamate moiety as histone deacetylase inhibitors and potent antitumor agents.
    Xie R, Li Y, Tang P, Yuan Q.
    Eur J Med Chem; 2018 Jan 01; 143():320-333. PubMed ID: 29202397
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis, and molecular docking of novel pyrazole-chalcone analogs of lonazolac as 5-LOX, iNOS and tubulin polymerization inhibitors with potential anticancer and anti-inflammatory activities.
    Ahmed AHH, Mohamed MFA, Allam RM, Nafady A, Mohamed SK, Gouda AE, Beshr EAM.
    Bioorg Chem; 2022 Dec 01; 129():106171. PubMed ID: 36166898
    [Abstract] [Full Text] [Related]

  • 17. Synthesis, anticancer activity and molecular docking studies on 1,2-diarylbenzimidazole analogues as anti-tubulin agents.
    Zhang YL, Yang R, Xia LY, Man RJ, Chu YC, Jiang AQ, Wang ZC, Zhu HL.
    Bioorg Chem; 2019 Nov 01; 92():103219. PubMed ID: 31476616
    [Abstract] [Full Text] [Related]

  • 18. Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
    Alswah M, Bayoumi AH, Elgamal K, Elmorsy A, Ihmaid S, Ahmed HEA.
    Molecules; 2017 Dec 27; 23(1):. PubMed ID: 29280968
    [Abstract] [Full Text] [Related]

  • 19. Synthesis of different heterocycles-linked chalcone conjugates as cytotoxic agents and tubulin polymerization inhibitors.
    Shankaraiah N, Nekkanti S, Brahma UR, Praveen Kumar N, Deshpande N, Prasanna D, Senwar KR, Jaya Lakshmi U.
    Bioorg Med Chem; 2017 Sep 01; 25(17):4805-4816. PubMed ID: 28774575
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and anticancer activity of novel valproic acid conjugates with improved histone deacetylase (HDAC) inhibitory activity.
    Ibrahim TS, Sheha TA, Abo-Dya NE, AlAwadh MA, Alhakamy NA, Abdel-Samii ZK, Panda SS, Abuo-Rahma GEA, Mohamed MFA.
    Bioorg Chem; 2020 Jun 01; 99():103797. PubMed ID: 32247939
    [Abstract] [Full Text] [Related]

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