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Journal Abstract Search

189 related items for PubMed ID: 32872305

  • 1. Role of Poly [ADP-ribose] Polymerase 1 in Activating the Kirsten ras (KRAS) Gene in Response to Oxidative Stress.
    Cinque G, Ferino A, Pedersen EB, Xodo LE.
    Int J Mol Sci; 2020 Aug 28; 21(17):. PubMed ID: 32872305
    [Abstract] [Full Text] [Related]

  • 2. The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription.
    Cogoi S, Ferino A, Miglietta G, Pedersen EB, Xodo LE.
    Nucleic Acids Res; 2018 Jan 25; 46(2):661-676. PubMed ID: 29165690
    [Abstract] [Full Text] [Related]

  • 3. Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA.
    Cogoi S, Rapozzi V, Cauci S, Xodo LE.
    Biochim Biophys Acta Gen Subj; 2017 May 25; 1861(5 Pt B):1389-1398. PubMed ID: 27888145
    [Abstract] [Full Text] [Related]

  • 4. The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element.
    Cogoi S, Paramasivam M, Membrino A, Yokoyama KK, Xodo LE.
    J Biol Chem; 2010 Jul 16; 285(29):22003-16. PubMed ID: 20457603
    [Abstract] [Full Text] [Related]

  • 5. Effect of DNA Glycosylases OGG1 and Neil1 on Oxidized G-Rich Motif in the KRAS Promoter.
    Ferino A, Xodo LE.
    Int J Mol Sci; 2021 Jan 24; 22(3):. PubMed ID: 33498912
    [Abstract] [Full Text] [Related]

  • 6. MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice.
    Cogoi S, Zorzet S, Rapozzi V, Géci I, Pedersen EB, Xodo LE.
    Nucleic Acids Res; 2013 Apr 24; 41(7):4049-64. PubMed ID: 23471001
    [Abstract] [Full Text] [Related]

  • 7. Protein hnRNPA1 binds to a critical G-rich element of KRAS and unwinds G-quadruplex structures: implications in transcription.
    Xodo L, Paramasivam M, Membrino A, Cogoi S.
    Nucleic Acids Symp Ser (Oxf); 2008 Apr 24; (52):159-60. PubMed ID: 18776302
    [Abstract] [Full Text] [Related]

  • 8. Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription.
    Paramasivam M, Membrino A, Cogoi S, Fukuda H, Nakagama H, Xodo LE.
    Nucleic Acids Res; 2009 May 24; 37(9):2841-53. PubMed ID: 19282454
    [Abstract] [Full Text] [Related]

  • 9. G4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy.
    Membrino A, Cogoi S, Pedersen EB, Xodo LE.
    PLoS One; 2011 May 24; 6(9):e24421. PubMed ID: 21931711
    [Abstract] [Full Text] [Related]

  • 10. The human AP-endonuclease 1 (APE1) is a DNA G-quadruplex structure binding protein and regulates KRAS expression in pancreatic ductal adenocarcinoma cells.
    Pramanik S, Chen Y, Song H, Khutsishvili I, Marky LA, Ray S, Natarajan A, Singh PK, Bhakat KK.
    Nucleic Acids Res; 2022 Apr 08; 50(6):3394-3412. PubMed ID: 35286386
    [Abstract] [Full Text] [Related]

  • 11. Insight into the Complexity of the i-Motif and G-Quadruplex DNA Structures Formed in the KRAS Promoter and Subsequent Drug-Induced Gene Repression.
    Kaiser CE, Van Ert NA, Agrawal P, Chawla R, Yang D, Hurley LH.
    J Am Chem Soc; 2017 Jun 28; 139(25):8522-8536. PubMed ID: 28570076
    [Abstract] [Full Text] [Related]

  • 12. An oncogenic KRAS transcription program activates the RHOGEF ARHGEF2 to mediate transformed phenotypes in pancreatic cancer.
    Kent OA, Sandí MJ, Burston HE, Brown KR, Rottapel R.
    Oncotarget; 2017 Jan 17; 8(3):4484-4500. PubMed ID: 27835861
    [Abstract] [Full Text] [Related]

  • 13. Identification and characterization of a new G-quadruplex forming region within the kRAS promoter as a transcriptional regulator.
    Morgan RK, Batra H, Gaerig VC, Hockings J, Brooks TA.
    Biochim Biophys Acta; 2016 Feb 17; 1859(2):235-45. PubMed ID: 26597160
    [Abstract] [Full Text] [Related]

  • 14. G-Quadruplex loops regulate PARP-1 enzymatic activation.
    Edwards AD, Marecki JC, Byrd AK, Gao J, Raney KD.
    Nucleic Acids Res; 2021 Jan 11; 49(1):416-431. PubMed ID: 33313902
    [Abstract] [Full Text] [Related]

  • 15. HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property.
    Cogoi S, Shchekotikhin AE, Xodo LE.
    Nucleic Acids Res; 2014 Jul 11; 42(13):8379-88. PubMed ID: 25013182
    [Abstract] [Full Text] [Related]

  • 16. PARP-1 activation after oxidative insult promotes energy stress-dependent phosphorylation of YAP1 and reduces cell viability.
    Martín-Guerrero SM, Casado P, Hijazi M, Rajeeve V, Plaza-Díaz J, Abadía-Molina F, Navascués J, Cuadros MA, Cutillas PR, Martín-Oliva D.
    Biochem J; 2020 Dec 11; 477(23):4491-4513. PubMed ID: 33146386
    [Abstract] [Full Text] [Related]

  • 17. KRAS promoter oligonucleotide with decoy activity dimerizes into a unique topology consisting of two G-quadruplex units.
    Podbevšek P, Plavec J.
    Nucleic Acids Res; 2016 Jan 29; 44(2):917-25. PubMed ID: 26656490
    [Abstract] [Full Text] [Related]

  • 18. RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation.
    Miglietta G, Cogoi S, Marinello J, Capranico G, Tikhomirov AS, Shchekotikhin A, Xodo LE.
    J Med Chem; 2017 Dec 14; 60(23):9448-9461. PubMed ID: 29140695
    [Abstract] [Full Text] [Related]

  • 19. Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome.
    Roychoudhury S, Pramanik S, Harris HL, Tarpley M, Sarkar A, Spagnol G, Sorgen PL, Chowdhury D, Band V, Klinkebiel D, Bhakat KK.
    Proc Natl Acad Sci U S A; 2020 May 26; 117(21):11409-11420. PubMed ID: 32404420
    [Abstract] [Full Text] [Related]

  • 20. Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins.
    Cogoi S, Paramasivam M, Spolaore B, Xodo LE.
    Nucleic Acids Res; 2008 Jun 26; 36(11):3765-80. PubMed ID: 18490377
    [Abstract] [Full Text] [Related]

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