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Journal Abstract Search

194 related items for PubMed ID: 32910221

  • 1. Deletion of obscurin immunoglobulin domains Ig58/59 leads to age-dependent cardiac remodeling and arrhythmia.
    Grogan A, Coleman A, Joca H, Granzier H, Russel MW, Ward CW, Kontrogianni-Konstantopoulos A.
    Basic Res Cardiol; 2020 Sep 10; 115(6):60. PubMed ID: 32910221
    [Abstract] [Full Text] [Related]

  • 2. Alterations in cytoskeletal and Ca2+ cycling regulators in atria lacking the obscurin Ig58/59 module.
    Grogan A, Huang W, Brong A, Kane MA, Kontrogianni-Konstantopoulos A.
    Front Cardiovasc Med; 2023 Sep 10; 10():1085840. PubMed ID: 37304957
    [Abstract] [Full Text] [Related]

  • 3. Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin.
    Hu LR, Ackermann MA, Hecker PA, Prosser BL, King B, O'Connell KA, Grogan A, Meyer LC, Berndsen CE, Wright NT, Jonathan Lederer W, Kontrogianni-Konstantopoulos A.
    Sci Adv; 2017 Jun 10; 3(6):e1603081. PubMed ID: 28630914
    [Abstract] [Full Text] [Related]

  • 4. Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors.
    Valverde CA, Mazzocchi G, Di Carlo MN, Ciocci Pardo A, Salas N, Ragone MI, Felice JI, Cely-Ortiz A, Consolini AE, Portiansky E, Mosca S, Kranias EG, Wehrens XHT, Mattiazzi A.
    Cardiovasc Res; 2019 Mar 01; 115(3):556-569. PubMed ID: 30169578
    [Abstract] [Full Text] [Related]

  • 5. When is an obscurin variant pathogenic? The impact of Arg4344Gln and Arg4444Trp variants on protein-protein interactions and protein stability.
    Fukuzawa A, Koch D, Grover S, Rees M, Gautel M.
    Hum Mol Genet; 2021 Jun 09; 30(12):1131-1141. PubMed ID: 33438037
    [Abstract] [Full Text] [Related]

  • 6. Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814.
    Mazzocchi G, Sommese L, Palomeque J, Felice JI, Di Carlo MN, Fainstein D, Gonzalez P, Contreras P, Skapura D, McCauley MD, Lascano EC, Negroni JA, Kranias EG, Wehrens XH, Valverde CA, Mattiazzi A.
    J Physiol; 2016 Jun 01; 594(11):3005-30. PubMed ID: 26695843
    [Abstract] [Full Text] [Related]

  • 7. Increased intracellular Ca2+ and SR Ca2+ load contribute to arrhythmias after acidosis in rat heart. Role of Ca2+/calmodulin-dependent protein kinase II.
    Said M, Becerra R, Palomeque J, Rinaldi G, Kaetzel MA, Diaz-Sylvester PL, Copello JA, Dedman JR, Mundiña-Weilenmann C, Vittone L, Mattiazzi A.
    Am J Physiol Heart Circ Physiol; 2008 Oct 01; 295(4):H1669-83. PubMed ID: 18723772
    [Abstract] [Full Text] [Related]

  • 8. O-GlcNAc Transferase Promotes Compensated Cardiac Function and Protein Kinase A O-GlcNAcylation During Early and Established Pathological Hypertrophy From Pressure Overload.
    Zhu WZ, El-Nachef D, Yang X, Ledee D, Olson AK.
    J Am Heart Assoc; 2019 Jun 04; 8(11):e011260. PubMed ID: 31131693
    [Abstract] [Full Text] [Related]

  • 9. A novel human R25C-phospholamban mutation is associated with super-inhibition of calcium cycling and ventricular arrhythmia.
    Liu GS, Morales A, Vafiadaki E, Lam CK, Cai WF, Haghighi K, Adly G, Hershberger RE, Kranias EG.
    Cardiovasc Res; 2015 Jul 01; 107(1):164-74. PubMed ID: 25852082
    [Abstract] [Full Text] [Related]

  • 10. Impaired Intracellular Ca2+ Dynamics, M-Band and Sarcomere Fragility in Skeletal Muscles of Obscurin KO Mice.
    Pierantozzi E, Szentesi P, Paolini C, Dienes B, Fodor J, Oláh T, Colombini B, Rassier DE, Rubino EM, Lange S, Rossi D, Csernoch L, Bagni MA, Reggiani C, Sorrentino V.
    Int J Mol Sci; 2022 Jan 24; 23(3):. PubMed ID: 35163243
    [Abstract] [Full Text] [Related]

  • 11. Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice.
    Bai Y, Jones PP, Guo J, Zhong X, Clark RB, Zhou Q, Wang R, Vallmitjana A, Benitez R, Hove-Madsen L, Semeniuk L, Guo A, Song LS, Duff HJ, Chen SR.
    Circ Res; 2013 Aug 16; 113(5):517-26. PubMed ID: 23856523
    [Abstract] [Full Text] [Related]

  • 12. Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve.
    Li L, Li J, Drum BM, Chen Y, Yin H, Guo X, Luckey SW, Gilbert ML, McKnight GS, Scott JD, Santana LF, Liu Q.
    Cardiovasc Res; 2017 Feb 16; 113(2):147-159. PubMed ID: 27856611
    [Abstract] [Full Text] [Related]

  • 13. Differential effects of phospholamban and Ca2+/calmodulin-dependent kinase II on [Ca2+]i transients in cardiac myocytes at physiological stimulation frequencies.
    Werdich AA, Lima EA, Dzhura I, Singh MV, Li J, Anderson ME, Baudenbacher FJ.
    Am J Physiol Heart Circ Physiol; 2008 May 16; 294(5):H2352-62. PubMed ID: 18359893
    [Abstract] [Full Text] [Related]

  • 14. Intracellular calcium current disorder and disease phenotype in OBSCN mutant iPSC-based cardiomyocytes in arrhythmogenic right ventricular cardiomyopathy.
    Chen P, Xiao Y, Wang Y, Zheng Z, Chen L, Yang X, Li J, Wu W, Zhang S.
    Theranostics; 2020 May 16; 10(24):11215-11229. PubMed ID: 33042279
    [Abstract] [Full Text] [Related]

  • 15. Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy.
    Røe ÅT, Aronsen JM, Skårdal K, Hamdani N, Linke WA, Danielsen HE, Sejersted OM, Sjaastad I, Louch WE.
    Cardiovasc Res; 2017 Aug 01; 113(10):1161-1172. PubMed ID: 28472418
    [Abstract] [Full Text] [Related]

  • 16. Rho-kinase inhibition reverses impaired Ca2+ handling and associated left ventricular dysfunction in pressure overload-induced cardiac hypertrophy.
    Olgar Y, Celen MC, Yamasan BE, Ozturk N, Turan B, Ozdemir S.
    Cell Calcium; 2017 Nov 01; 67():81-90. PubMed ID: 29029794
    [Abstract] [Full Text] [Related]

  • 17. Overexpression of heart-specific small subunit of myosin light chain phosphatase results in heart failure and conduction disturbance.
    Arimura T, Muchir A, Kuwahara M, Morimoto S, Ishikawa T, Du CK, Zhan DY, Nakao S, Machida N, Tanaka R, Yamane Y, Hayashi T, Kimura A.
    Am J Physiol Heart Circ Physiol; 2018 Jun 01; 314(6):H1192-H1202. PubMed ID: 29451818
    [Abstract] [Full Text] [Related]

  • 18. Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice.
    Zhang T, Guo T, Mishra S, Dalton ND, Kranias EG, Peterson KL, Bers DM, Brown JH.
    Circ Res; 2010 Feb 05; 106(2):354-62. PubMed ID: 19959778
    [Abstract] [Full Text] [Related]

  • 19. Hydrogen peroxide-mediated SERCA cysteine 674 oxidation contributes to impaired cardiac myocyte relaxation in senescent mouse heart.
    Qin F, Siwik DA, Lancel S, Zhang J, Kuster GM, Luptak I, Wang L, Tong X, Kang YJ, Cohen RA, Colucci WS.
    J Am Heart Assoc; 2013 Aug 20; 2(4):e000184. PubMed ID: 23963753
    [Abstract] [Full Text] [Related]

  • 20. MCU overexpression evokes disparate dose-dependent effects on mito-ROS and spontaneous Ca2+ release in hypertrophic rat cardiomyocytes.
    Hamilton S, Terentyeva R, Perger F, Hernández Orengo B, Martin B, Gorr MW, Belevych AE, Clements RT, Györke S, Terentyev D.
    Am J Physiol Heart Circ Physiol; 2021 Oct 01; 321(4):H615-H632. PubMed ID: 34415186
    [Abstract] [Full Text] [Related]

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