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Journal Abstract Search

376 related items for PubMed ID: 32912434

  • 1. A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors.
    Barnes NG, Parker AW, Ahmed Mal Ullah AA, Ragazzon PA, Hadfield JA.
    Bioorg Med Chem; 2020 Oct 01; 28(19):115684. PubMed ID: 32912434
    [Abstract] [Full Text] [Related]

  • 2. Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
    Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM.
    J Enzyme Inhib Med Chem; 2021 Dec 01; 36(1):802-818. PubMed ID: 33730937
    [Abstract] [Full Text] [Related]

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  • 4. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
    Jadala C, Sathish M, Anchi P, Tokala R, Lakshmi UJ, Reddy VG, Shankaraiah N, Godugu C, Kamal A.
    ChemMedChem; 2019 Dec 17; 14(24):2052-2060. PubMed ID: 31674147
    [Abstract] [Full Text] [Related]

  • 5. Novel Combretastatin A-4 Analogs-Design, Synthesis, and Antiproliferative and Anti-Tubulin Activity.
    Jędrzejczyk M, Morabito B, Żyżyńska-Granica B, Struga M, Janczak J, Aminpour M, Tuszynski JA, Huczyński A.
    Molecules; 2024 May 08; 29(10):. PubMed ID: 38792062
    [Abstract] [Full Text] [Related]

  • 6. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY, Yang MF, Chang CY, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Oct 19; 49(21):6412-5. PubMed ID: 17034147
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis and antiproliferative activity of the new conjugates of E7010 and resveratrol as tubulin polymerization inhibitors.
    Kamal A, Ashraf M, Basha ST, Ali Hussaini SM, Singh S, Vishnuvardhan MV, Kiran B, Sridhar B.
    Org Biomol Chem; 2016 Jan 28; 14(4):1382-94. PubMed ID: 26676480
    [Abstract] [Full Text] [Related]

  • 8. Potent combretastatin A-4 analogs containing 1,2,4-triazole: Synthesis, antiproliferative, anti-tubulin activity, and docking study.
    Mustafa M, Anwar S, Elgamal F, Ahmed ER, Aly OM.
    Eur J Med Chem; 2019 Dec 01; 183():111697. PubMed ID: 31536891
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y.
    Eur J Med Chem; 2018 Jan 20; 144():817-842. PubMed ID: 29306206
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells.
    Zhang H, Li M, Zhou X, Tang L, Chen G, Zhang Y.
    Eur J Med Chem; 2024 Jun 05; 272():116497. PubMed ID: 38759453
    [Abstract] [Full Text] [Related]

  • 11. Design, concise synthesis and evaluation of novel amide-based combretastatin A-4 analogues as potent tubulin inhibitors.
    Ma Y, Wang T, Cheng L, Ma X, Li R, Zhang M, Chen J, Zhao P.
    Bioorg Med Chem Lett; 2024 Aug 01; 108():129816. PubMed ID: 38806101
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
    Penthala NR, Zong H, Ketkar A, Madadi NR, Janganati V, Eoff RL, Guzman ML, Crooks PA.
    Eur J Med Chem; 2015 Mar 06; 92():212-20. PubMed ID: 25557492
    [Abstract] [Full Text] [Related]

  • 13. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
    Liu R, Zhang S, Huang M, Guo Z, Li L, Li M, Wu L, Guan Q, Zhang W.
    Bioorg Chem; 2021 Oct 01; 115():105220. PubMed ID: 34352709
    [Abstract] [Full Text] [Related]

  • 15. Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation.
    Pecnard S, Provot O, Levaique H, Bignon J, Askenatzis L, Saller F, Borgel D, Michallet S, Laisne MC, Lafanechère L, Alami M, Hamze A.
    Eur J Med Chem; 2021 Jan 01; 209():112873. PubMed ID: 33038796
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

  • 17. Design and synthesis of silicon-containing tubulin polymerization inhibitors: replacement of the ethylene moiety of combretastatin A-4 with a silicon linker.
    Nakamura M, Kajita D, Matsumoto Y, Hashimoto Y.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7381-91. PubMed ID: 24139940
    [Abstract] [Full Text] [Related]

  • 18. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 01; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, biological evaluation, and structure-activity relationships of new tubulin polymerization inhibitors based on 5-amino-1,2,4-triazole scaffold.
    Yang F, Chen L, Lai JM, Jian XE, Lv DX, Yuan LL, Liu YX, Liang FT, Zheng XL, Li XL, Wei LY, You WW, Zhao PL.
    Bioorg Med Chem Lett; 2021 Apr 15; 38():127880. PubMed ID: 33636303
    [Abstract] [Full Text] [Related]

  • 20. Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues.
    Theeramunkong S, Caldarelli A, Massarotti A, Aprile S, Caprioglio D, Zaninetti R, Teruggi A, Pirali T, Grosa G, Tron GC, Genazzani AA.
    J Med Chem; 2011 Jul 28; 54(14):4977-86. PubMed ID: 21696175
    [Abstract] [Full Text] [Related]

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