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Journal Abstract Search

123 related items for PubMed ID: 32945693

  • 1.
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  • 2. Approaches to Resolve False Reporting in Neutralizing Antibody Assays Caused by Reagent Leaching from Affinity Capture Elution Solid Phase.
    Xiang Y, Kamerud J, Donley J, Olson K, Caiazzo T, Yeung D, Parng C, Gorovits B.
    AAPS J; 2018 Nov 06; 21(1):4. PubMed ID: 30402825
    [Abstract] [Full Text] [Related]

  • 3. Approaches to improve drug tolerance and target tolerance in the assessment of neutralizing anti-drug antibodies.
    Wu B, Schnarr M, Devlin JL, Brown S, Yang TY.
    Bioanalysis; 2019 Nov 06; 11(22):2061-2074. PubMed ID: 31829737
    [Abstract] [Full Text] [Related]

  • 4. Neutralizing Antibody Assay Development with High Drug and Target Tolerance to Support Clinical Development of an Anti-TFPI Therapeutic Monoclonal Antibody.
    Xiang Y, Parng C, Olson K, Seletskaia E, Gorovits B, Jani D, Caiazzo T, Joyce A, Donley J.
    AAPS J; 2019 Mar 29; 21(3):46. PubMed ID: 30927117
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  • 6. Highly drug/target-tolerant neutralizing antibody (NAb) assay development through target-based drug depletion and drug-based NAb extraction for an anti-EGFR therapeutic monoclonal antibody.
    Fu R, Xu J, Guo Q, Liu T, Su X, Xu M, Zhao X, Wang F, Ji L, Qian W, Hou S, Li J, Zhang D, Guo H.
    J Pharm Biomed Anal; 2024 Apr 15; 241():116006. PubMed ID: 38309099
    [Abstract] [Full Text] [Related]

  • 7. Bead-extraction and heat-dissociation (BEHD): A novel way to overcome drug and matrix interference in immunogenicity testing.
    Xu W, Sank M, Cummings J, Carl S, Juhel M, Gleason C, Dodge R, DeSilva BS, Kolaitis G, Pillutla R.
    J Immunol Methods; 2018 Nov 15; 462():34-41. PubMed ID: 30099014
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  • 9. Development and characterization of a pre-treatment procedure to eliminate human monoclonal antibody therapeutic drug and matrix interference in cell-based functional neutralizing antibody assays.
    Xu W, Jiang H, Titsch C, Haulenbeek JR, Pillutla RC, Aubry AF, DeSilva BS, Arnold ME, Zeng J, Dodge RW.
    J Immunol Methods; 2015 Jan 15; 416():94-104. PubMed ID: 25445325
    [Abstract] [Full Text] [Related]

  • 10. Development of a Cell-based Neutralizing Antibody Assay for Zinpentraxin Alfa: Challenges and Mitigation Strategies.
    Yin Z, Guerrero J, Melendez R, Andrews B, Peng K.
    AAPS J; 2023 Jul 20; 25(5):75. PubMed ID: 37468730
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  • 12. Comparison of cell-based and non-cell-based assay platforms for the detection of clinically relevant anti-drug neutralizing antibodies for immunogenicity assessment of therapeutic proteins.
    Hu J, Wala I, Han H, Nagatani J, Barger T, Civoli F, Kaliyaperumal A, Zhuang Y, Gupta S.
    J Immunol Methods; 2015 Apr 20; 419():1-8. PubMed ID: 25795420
    [Abstract] [Full Text] [Related]

  • 13. Drug Removal Strategies in Competitive Ligand Binding Neutralizing Antibody (NAb) Assays: Highly Drug-Tolerant Methods and Interpreting Immunogenicity Data.
    Partridge MA, Karayusuf EK, Shyu G, Georgaros C, Torri A, Sumner G.
    AAPS J; 2020 Aug 17; 22(5):112. PubMed ID: 32808205
    [Abstract] [Full Text] [Related]

  • 14. An innovative method for characterizing neutralizing antibodies against antibody-derived therapeutics.
    Coddens A, Snoeck V, Bontinck L, Buyse MA, Pine SO.
    J Immunol Methods; 2020 Dec 17; 487():112896. PubMed ID: 33065122
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  • 16. Development of an enzymatic assay for the detection of neutralizing antibodies against therapeutic angiotensin-converting enzyme 2 (ACE2).
    Liao K, Sikkema D, Wang C, Lee TN.
    J Immunol Methods; 2013 Mar 29; 389(1-2):52-60. PubMed ID: 23298658
    [Abstract] [Full Text] [Related]

  • 17. Addressing soluble target interference in the development of a functional assay for the detection of neutralizing antibodies against a BCMA-CD3 bispecific antibody.
    Wang Y, Luong M, Guadiz C, Zhang M, Gorovits B.
    J Immunol Methods; 2019 Nov 29; 474():112642. PubMed ID: 31400410
    [Abstract] [Full Text] [Related]

  • 18. Indirect assessment of neutralizing anti-drug antibodies utilizing pharmacokinetic assay data.
    Vettermann C, Ortiz J, Lee S, Sanchez S, Victor HP, Ma M, Heath T, Gupta S.
    J Immunol Methods; 2016 Feb 29; 429():28-38. PubMed ID: 26711311
    [Abstract] [Full Text] [Related]

  • 19. Unique challenges required reassessment and alterations to critical reagents to rescue a neutralizing antibody assay.
    Rowe BA, Medina-Carle K, Chen K, Reese KJ, McCarthy KM, Concannon AA, Gunn GR, Gehman AP, Jiang Y, Meyer E.
    Bioanalysis; 2024 Feb 29; 16(14):735-745. PubMed ID: 38884331
    [Abstract] [Full Text] [Related]

  • 20. Recommendations for the Development and Validation of Neutralizing Antibody Assays in Support of Biosimilar Assessment.
    Gouty D, Cai CC, Cai XY, Kasinath A, Kumar V, Alvandkouhi S, Yang J, Pederson S, Babbitt B, Peritt D, Rudy A, Koppenburg V, Dasilva A, Ullmann M, Liu S, Satterwhite C.
    AAPS J; 2017 Dec 28; 20(1):25. PubMed ID: 29285735
    [Abstract] [Full Text] [Related]

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