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174 related items for PubMed ID: 33066378
1. New Zileuton-Hydroxycinnamic Acid Hybrids: Synthesis and Structure-Activity Relationship towards 5-Lipoxygenase Inhibition. Chiasson AI, Robichaud S, Ndongou Moutombi FJ, Hébert MPA, Mbarik M, Surette ME, Touaibia M. Molecules; 2020 Oct 14; 25(20):. PubMed ID: 33066378 [Abstract] [Full Text] [Related]
2. Sinapic acid phenethyl ester as a potent selective 5-lipoxygenase inhibitor: Synthesis and structure-activity relationship. Touaibia M, Hébert MJG, Levesque NA, Doiron JA, Doucet MS, Jean-François J, Cormier M, Boudreau LH, Surette ME. Chem Biol Drug Des; 2018 Nov 14; 92(5):1876-1887. PubMed ID: 29953727 [Abstract] [Full Text] [Related]
3. Structure-Activity Relationship Studies of New Sinapic Acid Phenethyl Ester Analogues Targeting the Biosynthesis of 5-Lipoxygenase Products: The Role of Phenolic Moiety, Ester Function, and Bioisosterism. Touaibia M, Faye DC, Doiron JA, Chiasson AI, Blanchard S, Roy PP, Surette ME. J Nat Prod; 2022 Jan 28; 85(1):225-236. PubMed ID: 34995066 [Abstract] [Full Text] [Related]
4. New Hydroxycinnamic Acid Esters as Novel 5-Lipoxygenase Inhibitors That Affect Leukotriene Biosynthesis. Boudreau LH, Lassalle-Claux G, Cormier M, Blanchard S, Doucet MS, Surette ME, Touaibia M. Mediators Inflamm; 2017 Jan 28; 2017():6904634. PubMed ID: 28680195 [Abstract] [Full Text] [Related]
5. Structure-activity relationship of caffeic acid phenethyl ester analogs as new 5-lipoxygenase inhibitors. Doiron JA, Leblanc LM, Hébert MJ, Levesque NA, Paré AF, Jean-François J, Cormier M, Surette ME, Touaibia M. Chem Biol Drug Des; 2017 Apr 28; 89(4):514-528. PubMed ID: 27717142 [Abstract] [Full Text] [Related]
6. Discovery of a novel 2,5-dihydroxycinnamic acid-based 5-lipoxygenase inhibitor that induces apoptosis and may impair autophagic flux in RCC4 renal cancer cells. Selka A, Doiron JA, Lyons P, Dastous S, Chiasson A, Cormier M, Turcotte S, Surette ME, Touaibia M. Eur J Med Chem; 2019 Oct 01; 179():347-357. PubMed ID: 31260889 [Abstract] [Full Text] [Related]
7. Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytes. Boudreau LH, Maillet J, LeBlanc LM, Jean-François J, Touaibia M, Flamand N, Surette ME. PLoS One; 2012 Oct 01; 7(2):e31833. PubMed ID: 22347509 [Abstract] [Full Text] [Related]
8. Multitarget drugs: synthesis and preliminary pharmacological characterization of zileuton analogues endowed with Dual 5-LO inhibitor and NO-dependent activities. Boschi D, Giorgis M, Cena C, Talniya NC, Di Stilo A, Morini G, Coruzzi G, Guaita E, Fruttero R, Gasco A. ChemMedChem; 2010 Sep 03; 5(9):1444-9. PubMed ID: 20645382 [No Abstract] [Full Text] [Related]
9. Single and multiple inhibitors of the biosynthesis of 5-, 12-, 15-lipoxygenase products derived from cinnamyl-3,4-dihydroxy-α-cyanocinnamate: Synthesis and structure-activity relationship. Touaibia M, Chiasson AI, Robichaud S, Doiron JA, Hébert MPA, Surette ME. Drug Dev Res; 2024 May 03; 85(3):e22181. PubMed ID: 38619209 [Abstract] [Full Text] [Related]
10. Phenolic acid phenethylesters and their corresponding ketones: Inhibition of 5-lipoxygenase and stability in human blood and HepaRG cells. Mbarik M, Poirier SJ, Doiron J, Selka A, Barnett DA, Cormier M, Touaibia M, Surette ME. Pharmacol Res Perspect; 2019 Oct 03; 7(5):e00524. PubMed ID: 31523435 [Abstract] [Full Text] [Related]
13. N-Aminoindoline derivatives as inhibitors of 5-lipoxygenase. Audouin C, Mestdagh N, Lassoie MA, Houssin R, Hénichart JP. Bioorg Med Chem Lett; 2001 Mar 26; 11(6):845-8. PubMed ID: 11277534 [Abstract] [Full Text] [Related]
14. Design, synthesis and evaluation of semi-synthetic triazole-containing caffeic acid analogues as 5-lipoxygenase inhibitors. De Lucia D, Lucio OM, Musio B, Bender A, Listing M, Dennhardt S, Koeberle A, Garscha U, Rizzo R, Manfredini S, Werz O, Ley SV. Eur J Med Chem; 2015 Aug 28; 101():573-83. PubMed ID: 26197161 [Abstract] [Full Text] [Related]
15. Effect of zileuton and celecoxib on urinary LTE4 and PGE-M levels in smokers. Mohebati A, Milne GL, Zhou XK, Duffield-Lillico AJ, Boyle JO, Knutson A, Bosworth BP, Kingsley PJ, Marnett LJ, Brown PH, Akpa EG, Szabo E, Dannenberg AJ. Cancer Prev Res (Phila); 2013 Jul 28; 6(7):646-55. PubMed ID: 23682075 [Abstract] [Full Text] [Related]
16. NMR metabolomics analysis of the effects of 5-lipoxygenase inhibitors on metabolism in glioblastomas. Morin P, Ferguson D, LeBlanc LM, Hébert MJ, Paré AF, Jean-François J, Surette ME, Touaibia M, Cuperlovic-Culf M. J Proteome Res; 2013 May 03; 12(5):2165-76. PubMed ID: 23557402 [Abstract] [Full Text] [Related]
19. Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase. Filosa R, Peduto A, Aparoy P, Schaible AM, Luderer S, Krauth V, Petronzi C, Massa A, de Rosa M, Reddanna P, Werz O. Eur J Med Chem; 2013 Sep 03; 67():269-79. PubMed ID: 23871907 [Abstract] [Full Text] [Related]