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117 related items for PubMed ID: 3307790

  • 1. Phosphorolytic cleavage of 2-fluoroadenine from 9-beta-D-arabinofuranosyl-2-fluoroadenine by Escherichia coli. A pathway for 2-fluoro-ATP production.
    Huang P, Plunkett W.
    Biochem Pharmacol; 1987 Sep 15; 36(18):2945-50. PubMed ID: 3307790
    [Abstract] [Full Text] [Related]

  • 2. 2-fluoro-ATP: a toxic metabolite of 9-beta-D-arabinosyl-2-fluoroadenine.
    Avramis VI, Plunkett W.
    Biochem Biophys Res Commun; 1983 May 31; 113(1):35-43. PubMed ID: 6860342
    [Abstract] [Full Text] [Related]

  • 3. Effects of 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate.
    Parker WB, Shaddix SC, Chang CH, White EL, Rose LM, Brockman RW, Shortnacy AT, Montgomery JA, Secrist JA, Bennett LL.
    Cancer Res; 1991 May 01; 51(9):2386-94. PubMed ID: 1707752
    [Abstract] [Full Text] [Related]

  • 4. Proposed mechanism of therapeutic selectivity for 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia based upon lower capacities for transport and phosphorylation in proliferative intestinal epithelium compared to tumor cells.
    Barrueco JR, Jacobsen DM, Chang CH, Brockman RW, Sirotnak FM.
    Cancer Res; 1987 Feb 01; 47(3):700-6. PubMed ID: 3802076
    [Abstract] [Full Text] [Related]

  • 5. Modulation of arabinosylnucleoside metabolism by arabinosylnucleotides in human leukemia cells.
    Gandhi V, Plunkett W.
    Cancer Res; 1988 Jan 15; 48(2):329-34. PubMed ID: 3335008
    [Abstract] [Full Text] [Related]

  • 6. Metabolism and therapeutic efficacy of 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia P388.
    Avramis VI, Plunkett W.
    Cancer Res; 1982 Jul 15; 42(7):2587-91. PubMed ID: 7083151
    [Abstract] [Full Text] [Related]

  • 7. Resistance to 9-beta-D-arabinofuranosyl-2-fluoroadenine due to reduced incorporation into DNA from competition by excess deoxyadenosine triphosphate: implications for different sensitivities to nucleoside analogues.
    Yoshio N, Kawai Y, Hori H, Ueda T.
    Int J Hematol; 2005 Jun 15; 81(5):405-12. PubMed ID: 16158821
    [Abstract] [Full Text] [Related]

  • 8. Comparison of the actions of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 9-beta-D-arabinofuranosyladenine on target enzymes from mouse tumor cells.
    White EL, Shaddix SC, Brockman RW, Bennett LL.
    Cancer Res; 1982 Jun 15; 42(6):2260-4. PubMed ID: 7042080
    [Abstract] [Full Text] [Related]

  • 9. Synergistic inhibition of leukemia L1210 cell growth in vitro by combinations of 2-fluoroadenine nucleosides and hydroxyurea or 2,3-dihydro-1H-pyrazole[2,3-a]imidazole.
    Sato A, Montgomery JA, Cory JG.
    Cancer Res; 1984 Aug 15; 44(8):3286-90. PubMed ID: 6611198
    [Abstract] [Full Text] [Related]

  • 10. Termination of DNA synthesis by 9-beta-D-arabinofuranosyl-2-fluoroadenine. A mechanism for cytotoxicity.
    Huang P, Chubb S, Plunkett W.
    J Biol Chem; 1990 Sep 25; 265(27):16617-25. PubMed ID: 1697861
    [Abstract] [Full Text] [Related]

  • 11. Metabolism and chemotherapeutic activity of 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia L1210 and evidence for its phosphorylation by deoxycytidine kinase.
    Brockman RW, Cheng YC, Schabel FM, Montgomery JA.
    Cancer Res; 1980 Oct 25; 40(10):3610-5. PubMed ID: 6254636
    [Abstract] [Full Text] [Related]

  • 12. Interactions between 2-fluoroadenine 9-beta-D-arabinofuranoside and the kinase inhibitor UCN-01 in human leukemia and lymphoma cells.
    Harvey S, Decker R, Dai Y, Schaefer G, Tang L, Kramer L, Dent P, Grant S.
    Clin Cancer Res; 2001 Feb 25; 7(2):320-30. PubMed ID: 11234887
    [Abstract] [Full Text] [Related]

  • 13. Metabolism of 9-beta-D-arabinosyl-2-fluoroadenine-5'-phosphate by mice bearing P388 leukemia.
    Avramis VI, Plunkett W.
    Cancer Drug Deliv; 1983 Feb 25; 1(1):1-10. PubMed ID: 6085754
    [Abstract] [Full Text] [Related]

  • 14. Mechanisms responsible for resistance of sublines derived from leukemia cell lines to an antitumor agent 9-beta-D-arabinofuranosyl-2-fluoroadenine.
    Bai L, Yamaguchi M, Tatsumi M, Kon K, Bräutigam M.
    J Cancer Res Clin Oncol; 1998 Feb 25; 124(7):367-73. PubMed ID: 9719499
    [Abstract] [Full Text] [Related]

  • 15. The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors.
    Parker WB, Allan PW, Waud WR, Hong J, Gilbert-Ross M, Achyut BR, Joshi D, Behbahani T, Rab R, Ealick SE, Sorscher EJ.
    Cancer Chemother Pharmacol; 2020 Mar 25; 85(3):573-583. PubMed ID: 31915968
    [Abstract] [Full Text] [Related]

  • 16. Comparison between the plasma and intracellular pharmacology of 1-beta-D-arabinofuranosylcytosine and 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-monophosphate in patients with relapsed leukemia.
    Danhauser L, Plunkett W, Liliemark J, Gandhi V, Iacoboni S, Keating M.
    Leukemia; 1987 Sep 25; 1(9):638-43. PubMed ID: 3478543
    [Abstract] [Full Text] [Related]

  • 17. Metabolism and metabolic actions of 6-methylpurine and 2-fluoroadenine in human cells.
    Parker WB, Allan PW, Shaddix SC, Rose LM, Speegle HF, Gillespie GY, Bennett LL.
    Biochem Pharmacol; 1998 May 15; 55(10):1673-81. PubMed ID: 9634004
    [Abstract] [Full Text] [Related]

  • 18. A comparison of the transportability, and its role in cytotoxicity, of clofarabine, cladribine, and fludarabine by recombinant human nucleoside transporters produced in three model expression systems.
    King KM, Damaraju VL, Vickers MF, Yao SY, Lang T, Tackaberry TE, Mowles DA, Ng AM, Young JD, Cass CE.
    Mol Pharmacol; 2006 Jan 15; 69(1):346-53. PubMed ID: 16234483
    [Abstract] [Full Text] [Related]

  • 19. Interaction of arabinosyl nucleotides in K562 human leukemia cells.
    Gandhi V, Plunkett W.
    Biochem Pharmacol; 1989 Oct 15; 38(20):3551-8. PubMed ID: 2479383
    [Abstract] [Full Text] [Related]

  • 20. 2'-Fluoro-2',3'-dideoxyarabinosyladenine: a metabolically stable analogue of the antiretroviral agent 2',3'-dideoxyadenosine.
    Masood R, Ahluwalia GS, Cooney DA, Fridland A, Marquez VE, Driscoll JS, Hao Z, Mitsuya H, Perno CF, Broder S.
    Mol Pharmacol; 1990 Apr 15; 37(4):590-6. PubMed ID: 2109183
    [Abstract] [Full Text] [Related]

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