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Journal Abstract Search

1400 related items for PubMed ID: 33113414

  • 21. Discovery of new quinoxaline-2(1H)-one-based anticancer agents targeting VEGFR-2 as inhibitors: Design, synthesis, and anti-proliferative evaluation.
    El-Adl K, Sakr HM, Yousef RG, Mehany ABM, Metwaly AM, Elhendawy MA, Radwan MM, ElSohly MA, Abulkhair HS, Eissa IH.
    Bioorg Chem; 2021 Sep; 114():105105. PubMed ID: 34175720
    [Abstract] [Full Text] [Related]

  • 22. Design, synthesis, molecular docking, in silico ADMET profile and anticancer evaluations of sulfonamide endowed with hydrazone-coupled derivatives as VEGFR-2 inhibitors.
    Sayed AM, Taher FA, Abdel-Samad MRK, El-Gaby MSA, El-Adl K, Saleh NM.
    Bioorg Chem; 2021 Mar; 108():104669. PubMed ID: 33515863
    [Abstract] [Full Text] [Related]

  • 23. Design, molecular modeling and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as inhibitors of topoisomerase II.
    El-Metwally SA, Khalil AK, El-Sayed WM.
    Bioorg Chem; 2020 Jan; 94():103492. PubMed ID: 31864673
    [Abstract] [Full Text] [Related]

  • 24. New quinoxaline derivatives as VEGFR-2 inhibitors with anticancer and apoptotic activity: Design, molecular modeling, and synthesis.
    Alsaif NA, Dahab MA, Alanazi MM, Obaidullah AJ, Al-Mehizia AA, Alanazi MM, Aldawas S, Mahdy HA, Elkady H.
    Bioorg Chem; 2021 May; 110():104807. PubMed ID: 33721808
    [Abstract] [Full Text] [Related]

  • 25. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
    My Van HT, Woo H, Jeong HM, Khadka DB, Yang SH, Zhao C, Jin Y, Lee ES, Youl Lee K, Kwon Y, Cho WJ.
    Eur J Med Chem; 2014 Jul 23; 82():181-94. PubMed ID: 24904965
    [Abstract] [Full Text] [Related]

  • 26. Design, green synthesis, molecular docking and anticancer evaluations of diazepam bearing sulfonamide moieties as VEGFR-2 inhibitors.
    Saleh NM, El-Gaby MSA, El-Adl K, Abd El-Sattar NEA.
    Bioorg Chem; 2020 Nov 23; 104():104350. PubMed ID: 33142416
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  • 29. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE, Gedawy EM.
    Eur J Med Chem; 2018 Apr 25; 150():403-418. PubMed ID: 29547830
    [Abstract] [Full Text] [Related]

  • 30. Rational Design, Synthesis, Molecular Docking, and Biological Evaluations of New Phenylpiperazine Derivatives of 1,2-Benzothiazine as Potential Anticancer Agents.
    Szczęśniak-Sięga BM, Zaręba N, Czyżnikowska Ż, Janek T, Kepinska M.
    Molecules; 2024 Sep 10; 29(18):. PubMed ID: 39339277
    [Abstract] [Full Text] [Related]

  • 31. Synthesis, computational study and biological evaluation of 9-acridinyl and 1-coumarinyl-1,2,3-triazole-4-yl derivatives as topoisomerase II inhibitors.
    Abdel-Hafez GA, Mohamed AI, Youssef AF, Simons C, Aboraia AS.
    J Enzyme Inhib Med Chem; 2022 Dec 10; 37(1):502-513. PubMed ID: 35012398
    [Abstract] [Full Text] [Related]

  • 32. Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies.
    Farouk F, Elmaaty AA, Elkamhawy A, Tawfik HO, Alnajjar R, Abourehab MAS, Saleh MA, Eldehna WM, Al-Karmalawy AA.
    J Enzyme Inhib Med Chem; 2023 Dec 10; 38(1):2171029. PubMed ID: 36701269
    [Abstract] [Full Text] [Related]

  • 33. Synthesis and biological evaluation of N-(carbobenzyloxy)-l-phenylalanine and N-(carbobenzyloxy)-l-aspartic acid-β-benzyl ester derivatives as potent topoisomerase IIα inhibitors.
    Han X, Zhong Y, Zhou G, Qi H, Li S, Ding Q, Liu Z, Song Y, Qiao X.
    Bioorg Med Chem; 2017 Jun 15; 25(12):3116-3126. PubMed ID: 28462840
    [Abstract] [Full Text] [Related]

  • 34. Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIα, G-quadruplex binding and cytotoxic properties.
    Palluotto F, Sosic A, Pinato O, Zoidis G, Catto M, Sissi C, Gatto B, Carotti A.
    Eur J Med Chem; 2016 Nov 10; 123():704-717. PubMed ID: 27521587
    [Abstract] [Full Text] [Related]

  • 35. N-Substituted-4-phenylphthalazin-1-amine-derived VEGFR-2 inhibitors: Design, synthesis, molecular docking, and anticancer evaluation studies.
    El-Adl K, Ibrahim MK, Khedr F, Abulkhair HS, Eissa IH.
    Arch Pharm (Weinheim); 2021 Mar 10; 354(3):e2000219. PubMed ID: 33197080
    [Abstract] [Full Text] [Related]

  • 36. Design, synthesis, molecular docking, and anticancer evaluations of 1-benzylquinazoline-2,4(1H,3H)-dione bearing different moieties as VEGFR-2 inhibitors.
    El-Adl K, El-Helby AA, Sakr H, El-Hddad SSA.
    Arch Pharm (Weinheim); 2020 Aug 10; 353(8):e2000068. PubMed ID: 32510731
    [Abstract] [Full Text] [Related]

  • 37. Design and Synthesis of Arylnaphthalene Lignan Lactone Derivatives as Potent Topoisomerase Inhibitors.
    Chen W, Feng Z, Hu D, Meng J.
    Med Chem; 2021 Aug 10; 17(8):856-865. PubMed ID: 32520691
    [Abstract] [Full Text] [Related]

  • 38. Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
    Alswah M, Bayoumi AH, Elgamal K, Elmorsy A, Ihmaid S, Ahmed HEA.
    Molecules; 2017 Dec 27; 23(1):. PubMed ID: 29280968
    [Abstract] [Full Text] [Related]

  • 39. Design, synthesis, biological evaluation and molecular docking study on peptidomimetic analogues of XK469.
    Xia QH, Hu W, Li C, Wu JF, Yang L, Han XM, Shen YM, Li ZY, Li X.
    Eur J Med Chem; 2016 Nov 29; 124():311-325. PubMed ID: 27597408
    [Abstract] [Full Text] [Related]

  • 40. Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors.
    Zhou DC, Lu YT, Mai YW, Zhang C, Xia J, Yao PF, Wang HG, Huang SL, Huang ZS.
    Bioorg Chem; 2019 Oct 29; 91():103131. PubMed ID: 31377387
    [Abstract] [Full Text] [Related]

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