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560 related items for PubMed ID: 33138354
1. Maxamycins: Durable Antibiotics Derived by Rational Redesign of Vancomycin. Wu ZC, Boger DL. Acc Chem Res; 2020 Nov 17; 53(11):2587-2599. PubMed ID: 33138354 [Abstract] [Full Text] [Related]
2. Peripheral modifications of [Ψ[CH2NH]Tpg4]vancomycin with added synergistic mechanisms of action provide durable and potent antibiotics. Okano A, Isley NA, Boger DL. Proc Natl Acad Sci U S A; 2017 Jun 27; 114(26):E5052-E5061. PubMed ID: 28559345 [Abstract] [Full Text] [Related]
3. Vancomycin C-Terminus Guanidine Modifications and Further Insights into an Added Mechanism of Action Imparted by a Peripheral Structural Modification. Wu ZC, Cameron MD, Boger DL. ACS Infect Dis; 2020 Aug 14; 6(8):2169-2180. PubMed ID: 32598127 [Abstract] [Full Text] [Related]
4. Total syntheses and initial evaluation of [Ψ[C(═S)NH]Tpg⁴]vancomycin, [Ψ[C(═NH)NH]Tpg⁴]vancomycin, [Ψ[CH₂NH]Tpg⁴]vancomycin, and their (4-chlorobiphenyl)methyl derivatives: synergistic binding pocket and peripheral modifications for the glycopeptide antibiotics. Okano A, Nakayama A, Wu K, Lindsey EA, Schammel AW, Feng Y, Collins KC, Boger DL. J Am Chem Soc; 2015 Mar 18; 137(10):3693-704. PubMed ID: 25750995 [Abstract] [Full Text] [Related]
6. Total synthesis of [Ψ[C(═NH)NH]Tpg(4)]vancomycin and its (4-chlorobiphenyl)methyl derivative: impact of peripheral modifications on vancomycin analogues redesigned for dual D-Ala-D-Ala and D-Ala-D-Lac binding. Okano A, Nakayama A, Schammel AW, Boger DL. J Am Chem Soc; 2014 Oct 01; 136(39):13522-5. PubMed ID: 25211770 [Abstract] [Full Text] [Related]
8. Quantum simulations of the structure and binding of glycopeptide antibiotic aglycons to cell wall analogues. Lee JG, Sagui C, Roland C. J Phys Chem B; 2005 Nov 03; 109(43):20588-96. PubMed ID: 16853665 [Abstract] [Full Text] [Related]
9. C1-CBP-vancomycin: Impact of a Vancomycin C-Terminus Trimethylammonium Cation on Pharmacological Properties and Insights into Its Newly Introduced Mechanism of Action. Wu ZC, Isley NA, Okano A, Weiss WJ, Boger DL. J Org Chem; 2020 Feb 07; 85(3):1365-1375. PubMed ID: 31670958 [Abstract] [Full Text] [Related]
10. Total synthesis of [Ψ[C(═S)NH]Tpg4]vancomycin aglycon, [Ψ[C(═NH)NH]Tpg4]vancomycin aglycon, and related key compounds: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding. Xie J, Okano A, Pierce JG, James RC, Stamm S, Crane CM, Boger DL. J Am Chem Soc; 2012 Jan 18; 134(2):1284-97. PubMed ID: 22188323 [Abstract] [Full Text] [Related]