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Journal Abstract Search

152 related items for PubMed ID: 3316665

  • 21. In the presence of CTP, UTP becomes an allosteric inhibitor of aspartate transcarbamoylase.
    Wild JR, Loughrey-Chen SJ, Corder TS.
    Proc Natl Acad Sci U S A; 1989 Jan; 86(1):46-50. PubMed ID: 2643106
    [Abstract] [Full Text] [Related]

  • 22. Functionally important arginine residues of aspartate transcarbamylase.
    Kantrowitz ER, Lipscomb WN.
    J Biol Chem; 1977 May 10; 252(9):2873-80. PubMed ID: 323257
    [Abstract] [Full Text] [Related]

  • 23. Importance of a conserved residue, aspartate-162, for the function of Escherichia coli aspartate transcarbamoylase.
    Newton CJ, Stevens RC, Kantrowitz ER.
    Biochemistry; 1992 Mar 24; 31(11):3026-32. PubMed ID: 1550826
    [Abstract] [Full Text] [Related]

  • 24. Communication between dissimilar subunits in aspartate transcarbamoylase: effect of inhibitor and activator on the conformation of the catalytic polypeptide chains.
    Hensley P, Schachman HK.
    Proc Natl Acad Sci U S A; 1979 Aug 24; 76(8):3732-6. PubMed ID: 386346
    [Abstract] [Full Text] [Related]

  • 25. A 3.0-A resolution study of nucleotide complexes with aspartate carbamoyltransferase.
    Honzatko RB, Monaco HL, Lipscomb WN.
    Proc Natl Acad Sci U S A; 1979 Oct 24; 76(10):5105-9. PubMed ID: 388429
    [Abstract] [Full Text] [Related]

  • 26. Structure of unligated aspartate carbamoyltransferase of Escherichia coli at 2.6-A resolution.
    Ke HM, Honzatko RB, Lipscomb WN.
    Proc Natl Acad Sci U S A; 1984 Jul 24; 81(13):4037-40. PubMed ID: 6377306
    [Abstract] [Full Text] [Related]

  • 27. Divergent allosteric patterns verify the regulatory paradigm for aspartate transcarbamylase.
    Wales ME, Madison LL, Glaser SS, Wild JR.
    J Mol Biol; 1999 Dec 17; 294(5):1387-400. PubMed ID: 10600393
    [Abstract] [Full Text] [Related]

  • 28. Interactions of metal-nucleotide complexes with aspartate carbamoyltransferase in the crystalline state.
    Honzatko RB, Lipscomb WN.
    Proc Natl Acad Sci U S A; 1982 Dec 17; 79(23):7171-4. PubMed ID: 6760190
    [Abstract] [Full Text] [Related]

  • 29. Arginine 54 in the active site of Escherichia coli aspartate transcarbamoylase is critical for catalysis: a site-specific mutagenesis, NMR, and X-ray crystallographic study.
    Stebbins JW, Robertson DE, Roberts MF, Stevens RC, Lipscomb WN, Kantrowitz ER.
    Protein Sci; 1992 Nov 17; 1(11):1435-46. PubMed ID: 1303763
    [Abstract] [Full Text] [Related]

  • 30. Heterotropic interactions in aspartate transcarbamoylase: turning allosteric ATP activation into inhibition as a consequence of a single tyrosine to phenylalanine mutation.
    Van Vliet F, Xi XG, De Staercke C, de Wannemaeker B, Jacobs A, Cherfils J, Ladjimi MM, Hervé G, Cunin R.
    Proc Natl Acad Sci U S A; 1991 Oct 15; 88(20):9180-3. PubMed ID: 1924381
    [Abstract] [Full Text] [Related]

  • 31. Homotropic effects in aspartate transcarbamoylase. What happens when the enzyme binds a single molecule of the bisubstrate analog N-phosphonacetyl-L-aspartate?
    Foote J, Schachman HK.
    J Mol Biol; 1985 Nov 05; 186(1):175-84. PubMed ID: 3908690
    [Abstract] [Full Text] [Related]

  • 32. The N-terminus of the regulatory chain of Escherichia coli aspartate transcarbamoylase is important for both nucleotide binding and heterotropic effects.
    Sakash JB, Kantrowitz ER.
    Biochemistry; 1998 Jan 06; 37(1):281-8. PubMed ID: 9425049
    [Abstract] [Full Text] [Related]

  • 33. The conserved residues glutamate-37, aspartate-100, and arginine-269 are important for the structural stabilization of Escherichia coli aspartate transcarbamoylase.
    Baker DP, Kantrowitz ER.
    Biochemistry; 1993 Sep 28; 32(38):10150-8. PubMed ID: 8104480
    [Abstract] [Full Text] [Related]

  • 34. Site-directed mutagenesis of a residue located in the regulatory site of Escherichia coli aspartate transcarbamoylase. Involvement of lysine 94 in effector binding and the allosteric mechanism.
    Zhang Y, Ladjimi MM, Kantrowitz ER.
    J Biol Chem; 1988 Jan 25; 263(3):1320-4. PubMed ID: 3121627
    [Abstract] [Full Text] [Related]

  • 35. Interactions of ionizable groups in Escherichia coli aspartate transcarbamylase with adenosine and cytidine 5'-triphosphates.
    Burz DS, Allewell NM.
    Biochemistry; 1982 Dec 21; 21(26):6647-55. PubMed ID: 6760892
    [No Abstract] [Full Text] [Related]

  • 36. New paradigm for allosteric regulation of Escherichia coli aspartate transcarbamoylase.
    Cockrell GM, Zheng Y, Guo W, Peterson AW, Truong JK, Kantrowitz ER.
    Biochemistry; 2013 Nov 12; 52(45):8036-47. PubMed ID: 24138583
    [Abstract] [Full Text] [Related]

  • 37. Asymmetric allosteric signaling in aspartate transcarbamoylase.
    Mendes KR, Martinez JA, Kantrowitz ER.
    ACS Chem Biol; 2010 May 21; 5(5):499-506. PubMed ID: 20210358
    [Abstract] [Full Text] [Related]

  • 38. Binding of regulatory nucleotides to aspartate transcarbamylase: nuclear magnetic resonance studies of selectively enriched carbon-13 regulatory subunit.
    Moore AC, Browne DT.
    Biochemistry; 1980 Dec 09; 19(25):5768-73. PubMed ID: 7006691
    [Abstract] [Full Text] [Related]

  • 39. The use of alanine scanning mutagenesis to determine the role of the N-terminus of the regulatory chain in the heterotropic mechanism of Escherichia coli aspartate transcarbamoylase.
    Dembowski NJ, Kantrowitz ER.
    Protein Eng; 1994 May 09; 7(5):673-9. PubMed ID: 8073037
    [Abstract] [Full Text] [Related]

  • 40. The activation of Escherichia coli aspartate transcarbamylase by ATP. Specific involvement of helix H2' at the hydrophobic interface between the two domains of the regulatory chains.
    Xi XG, De Staercke C, Van Vliet F, Triniolles F, Jacobs A, Stas PP, Ladjimi MM, Simon V, Cunin R, Hervé G.
    J Mol Biol; 1994 Sep 16; 242(2):139-49. PubMed ID: 8089837
    [Abstract] [Full Text] [Related]

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