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Journal Abstract Search


894 related items for PubMed ID: 33168021

  • 1. Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques.
    Natunen T, Martiskainen H, Marttinen M, Gabbouj S, Koivisto H, Kemppainen S, Kaipainen S, Takalo M, Svobodová H, Leppänen L, Kemiläinen B, Ryhänen S, Kuulasmaa T, Rahunen E, Juutinen S, Mäkinen P, Miettinen P, Rauramaa T, Pihlajamäki J, Haapasalo A, Leinonen V, Tanila H, Hiltunen M.
    Mol Neurodegener; 2020 Nov 10; 15(1):66. PubMed ID: 33168021
    [Abstract] [Full Text] [Related]

  • 2. Central vascular disease and exacerbated pathology in a mixed model of type 2 diabetes and Alzheimer's disease.
    Ramos-Rodriguez JJ, Jimenez-Palomares M, Murillo-Carretero MI, Infante-Garcia C, Berrocoso E, Hernandez-Pacho F, Lechuga-Sancho AM, Cozar-Castellano I, Garcia-Alloza M.
    Psychoneuroendocrinology; 2015 Dec 10; 62():69-79. PubMed ID: 26254770
    [Abstract] [Full Text] [Related]

  • 3. Role of Suppressor of Cytokine Signaling 3 (SOCS3) in Altering Activated Microglia Phenotype in APPswe/PS1dE9 Mice.
    Iwahara N, Hisahara S, Kawamata J, Matsumura A, Yokokawa K, Saito T, Fujikura M, Manabe T, Suzuki H, Matsushita T, Suzuki S, Shimohama S.
    J Alzheimers Dis; 2017 Dec 10; 55(3):1235-1247. PubMed ID: 27814300
    [Abstract] [Full Text] [Related]

  • 4. Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models.
    Sebastian Monasor L, Müller SA, Colombo AV, Tanrioever G, König J, Roth S, Liesz A, Berghofer A, Piechotta A, Prestel M, Saito T, Saido TC, Herms J, Willem M, Haass C, Lichtenthaler SF, Tahirovic S.
    Elife; 2020 Jun 08; 9():. PubMed ID: 32510331
    [Abstract] [Full Text] [Related]

  • 5. Metformin attenuates plaque-associated tau pathology and reduces amyloid-β burden in APP/PS1 mice.
    Chen Y, Zhao S, Fan Z, Li Z, Zhu Y, Shen T, Li K, Yan Y, Tian J, Liu Z, Zhang B.
    Alzheimers Res Ther; 2021 Feb 09; 13(1):40. PubMed ID: 33563332
    [Abstract] [Full Text] [Related]

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  • 7. The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease.
    von Saucken VE, Jay TR, Landreth GE.
    Neurobiol Dis; 2020 Nov 09; 145():105072. PubMed ID: 32890775
    [Abstract] [Full Text] [Related]

  • 8. Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model.
    Clayton K, Delpech JC, Herron S, Iwahara N, Ericsson M, Saito T, Saido TC, Ikezu S, Ikezu T.
    Mol Neurodegener; 2021 Mar 22; 16(1):18. PubMed ID: 33752701
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  • 10. TREM2 Overexpression has No Improvement on Neuropathology and Cognitive Impairment in Aging APPswe/PS1dE9 Mice.
    Jiang T, Wan Y, Zhang YD, Zhou JS, Gao Q, Zhu XC, Shi JQ, Lu H, Tan L, Yu JT.
    Mol Neurobiol; 2017 Mar 22; 54(2):855-865. PubMed ID: 26780455
    [Abstract] [Full Text] [Related]

  • 11. Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network.
    Takahashi H, Klein ZA, Bhagat SM, Kaufman AC, Kostylev MA, Ikezu T, Strittmatter SM, Alzheimer’s Disease Neuroimaging Initiative.
    Acta Neuropathol; 2017 May 22; 133(5):785-807. PubMed ID: 28070672
    [Abstract] [Full Text] [Related]

  • 12. Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice.
    Delizannis AT, Nonneman A, Tsering W, De Bondt A, Van den Wyngaert I, Zhang B, Meymand E, Olufemi MF, Koivula P, Maimaiti S, Trojanowski JQ, Lee VM, Brunden KR.
    Acta Neuropathol Commun; 2021 Sep 09; 9(1):150. PubMed ID: 34503586
    [Abstract] [Full Text] [Related]

  • 13. Mechanism of TREM2/DAP12 complex affecting β-amyloid plaque deposition in Alzheimer's disease modeled mice through mediating inflammatory response.
    Cui X, Qiao J, Liu S, Wu M, Gu W.
    Brain Res Bull; 2021 Jan 09; 166():21-28. PubMed ID: 33053435
    [Abstract] [Full Text] [Related]

  • 14. Early chronic suppression of microglial p38α in a model of Alzheimer's disease does not significantly alter amyloid-associated neuropathology.
    Braun DJ, Frazier HN, Davis VA, Coleman MJ, Rogers CB, Van Eldik LJ.
    PLoS One; 2023 Jan 09; 18(5):e0286495. PubMed ID: 37256881
    [Abstract] [Full Text] [Related]

  • 15. Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
    Meilandt WJ, Ngu H, Gogineni A, Lalehzadeh G, Lee SH, Srinivasan K, Imperio J, Wu T, Weber M, Kruse AJ, Stark KL, Chan P, Kwong M, Modrusan Z, Friedman BA, Elstrott J, Foreman O, Easton A, Sheng M, Hansen DV.
    J Neurosci; 2020 Feb 26; 40(9):1956-1974. PubMed ID: 31980586
    [Abstract] [Full Text] [Related]

  • 16. S14G-humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice.
    Zhang W, Zhang W, Li Z, Hao J, Zhang Z, Liu L, Mao N, Miao J, Zhang L.
    Pharmacol Biochem Behav; 2012 Jan 26; 100(3):361-9. PubMed ID: 21993310
    [Abstract] [Full Text] [Related]

  • 17. CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia.
    Lodder C, Scheyltjens I, Stancu IC, Botella Lucena P, Gutiérrez de Ravé M, Vanherle S, Vanmierlo T, Cremers N, Vanrusselt H, Brône B, Hanseeuw B, Octave JN, Bottelbergs A, Movahedi K, Dewachter I.
    Acta Neuropathol Commun; 2021 Jun 08; 9(1):108. PubMed ID: 34103079
    [Abstract] [Full Text] [Related]

  • 18. Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of Alzheimer´s disease and type two diabetes.
    Vargas-Soria M, Ramos-Rodriguez JJ, Del Marco A, Hierro-Bujalance C, Carranza-Naval MJ, Calvo-Rodriguez M, van Veluw SJ, Stitt AW, Simó R, Bacskai BJ, Infante-Garcia C, Garcia-Alloza M.
    Fluids Barriers CNS; 2022 Nov 07; 19(1):88. PubMed ID: 36345028
    [Abstract] [Full Text] [Related]

  • 19. Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
    Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK, Lin CC, Davis S, Ha C, Leung AW, Nguyen H, Chau R, Yulyaningsih E, Lopez I, Solanoy H, Masoud ST, Liang CC, Lin K, Astarita G, Khoury N, Zuchero JY, Thorne RG, Shen K, Miller S, Palop JJ, Garceau D, Sasner M, Whitesell JD, Harris JA, Hummel S, Gnörich J, Wind K, Kunze L, Zatcepin A, Brendel M, Willem M, Haass C, Barnett D, Zimmer TS, Orr AG, Scearce-Levie K, Lewcock JW, Di Paolo G, Sanchez PE.
    Mol Neurodegener; 2022 Jun 11; 17(1):41. PubMed ID: 35690868
    [Abstract] [Full Text] [Related]

  • 20. Upregulation of TREM2 Ameliorates Neuroinflammatory Responses and Improves Cognitive Deficits Triggered by Surgical Trauma in Appswe/PS1dE9 Mice.
    Jiang Y, Li Z, Ma H, Cao X, Liu F, Tian A, Sun X, Li X, Wang J.
    Cell Physiol Biochem; 2018 Jun 11; 46(4):1398-1411. PubMed ID: 29689568
    [Abstract] [Full Text] [Related]


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