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Journal Abstract Search

176 related items for PubMed ID: 33205981

  • 1. Exploration of Structure-Activity Relationship of Aromatic Aldehydes Bearing Pyridinylmethoxy-Methyl Esters as Novel Antisickling Agents.
    Pagare PP, Ghatge MS, Chen Q, Musayev FN, Venitz J, Abdulmalik O, Zhang Y, Safo MK.
    J Med Chem; 2020 Dec 10; 63(23):14724-14739. PubMed ID: 33205981
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  • 2. Rational design of pyridyl derivatives of vanillin for the treatment of sickle cell disease.
    Pagare PP, Ghatge MS, Musayev FN, Deshpande TM, Chen Q, Braxton C, Kim S, Venitz J, Zhang Y, Abdulmalik O, Safo MK.
    Bioorg Med Chem; 2018 May 15; 26(9):2530-2538. PubMed ID: 29655608
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  • 3. Rational modification of vanillin derivatives to stereospecifically destabilize sickle hemoglobin polymer formation.
    Deshpande TM, Pagare PP, Ghatge MS, Chen Q, Musayev FN, Venitz J, Zhang Y, Abdulmalik O, Safo MK.
    Acta Crystallogr D Struct Biol; 2018 Oct 01; 74(Pt 10):956-964. PubMed ID: 30289405
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  • 4. Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease.
    Xu GG, Pagare PP, Ghatge MS, Safo RP, Gazi A, Chen Q, David T, Alabbas AB, Musayev FN, Venitz J, Zhang Y, Safo MK, Abdulmalik O.
    Mol Pharm; 2017 Oct 02; 14(10):3499-3511. PubMed ID: 28858508
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  • 8. VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions.
    Abdulmalik O, Pagare PP, Huang B, Xu GG, Ghatge MS, Xu X, Chen Q, Anabaraonye N, Musayev FN, Omar AM, Venitz J, Zhang Y, Safo MK.
    Sci Rep; 2020 Nov 20; 10(1):20277. PubMed ID: 33219275
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  • 11. Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin.
    Abdulmalik O, Ghatge MS, Musayev FN, Parikh A, Chen Q, Yang J, Nnamani I, Danso-Danquah R, Eseonu DN, Asakura T, Abraham DJ, Venitz J, Safo MK.
    Acta Crystallogr D Biol Crystallogr; 2011 Nov 20; 67(Pt 11):920-8. PubMed ID: 22101818
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  • 12. Substituted benzaldehydes designed to increase the oxygen affinity of human haemoglobin and inhibit the sickling of sickle erythrocytes.
    Beddell CR, Goodford PJ, Kneen G, White RD, Wilkinson S, Wootton R.
    Br J Pharmacol; 1984 Jun 20; 82(2):397-407. PubMed ID: 6733364
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  • 13. Targeted modification of furan-2-carboxaldehydes into Michael acceptor analogs yielded long-acting hemoglobin modulators with dual antisickling activities.
    Omar AM, Abdulmalik O, El-Say KM, Ghatge MS, Cyril-Olutayo M, Paredes S, Al-Awadh M, El-Araby ME, Safo MK.
    Chem Biol Drug Des; 2024 Jan 20; 103(1):e14371. PubMed ID: 37798397
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  • 14. A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells.
    Nakagawa A, Ferrari M, Schleifer G, Cooper MK, Liu C, Yu B, Berra L, Klings ES, Safo RS, Chen Q, Musayev FN, Safo MK, Abdulmalik O, Bloch DB, Zapol WM.
    Mol Pharm; 2018 May 07; 15(5):1954-1963. PubMed ID: 29634905
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  • 16. Quantitative assessment of the in-vitro binding kinetics of antisickling aromatic aldehydes with hemoglobin A: A universal HPLC-UV/Vis method to quantitate Schiff-base adduct formation.
    Xu X, Ghatge MS, Huang B, Alghamdi A, Wang H, Pierce BD, Abdulmalik O, Zhang Y, Safo MK, Venitz J.
    J Pharm Biomed Anal; 2023 Jan 20; 223():115152. PubMed ID: 36399908
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  • 17. In vitro effects of NIPRISAN (Nix-0699): a naturally occurring, potent antisickling agent.
    Iyamu EW, Turner EA, Asakura T.
    Br J Haematol; 2002 Jul 20; 118(1):337-43. PubMed ID: 12100171
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  • 18. Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease.
    Huang B, Ghatge MS, Donkor AK, Musayev FN, Deshpande TM, Al-Awadh M, Alhashimi RT, Zhu H, Omar AM, Telen MJ, Zhang Y, McMahon TJ, Abdulmalik O, Safo MK.
    Molecules; 2022 Oct 12; 27(20):. PubMed ID: 36296435
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  • 19. O2 dependence of K+ transport in sickle cells: the effect of different cell populations and the substituted benzaldehyde 12C79.
    Gibson JS, Khan A, Speake PF, Ellory JC.
    FASEB J; 2001 Mar 12; 15(3):823-32. PubMed ID: 11259401
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  • 20. Quantitative structure-activity relationship of phenoxy and benzyloxy acid derivatives as antisickling agents.
    Mahran MA.
    Boll Chim Farm; 2000 Mar 12; 139(2):73-80. PubMed ID: 10920532
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