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Journal Abstract Search

253 related items for PubMed ID: 33222678

  • 1. Synthesis of N-acyl Derivatives of Aminocombretastatin A-4 and Study of their Interaction with Tubulin and Downregulation of c-Myc.
    Agut R, Falomir E, Murga J, Martín-Beltrán C, Gil-Edo R, Pla A, Carda M, Díaz JF, Josa-Prado F, Marco JA.
    Med Chem; 2021; 17(10):1129-1139. PubMed ID: 33222678
    [Abstract] [Full Text] [Related]

  • 2. Synthesis of Combretastatin A-4 and 3'-Aminocombretastatin A-4 derivatives with Aminoacid Containing Pendants and Study of Their Interaction with Tubulin and as Downregulators of the VEGF, hTERT and c-Myc Gene Expression.
    Agut R, Falomir E, Murga J, Martín-Beltrán C, Gil-Edo R, Pla A, Carda M, Marco JA.
    Molecules; 2020 Feb 04; 25(3):. PubMed ID: 32033084
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of carbamates derived from aminocombretastatin A-4 as vascular disrupting agents.
    Conesa-Milián L, Falomir E, Murga J, Carda M, Meyen E, Liekens S, Alberto Marco J.
    Eur J Med Chem; 2018 Mar 10; 147():183-193. PubMed ID: 29432949
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 Mar 10; 21(8):1047-1055. PubMed ID: 32981511
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS, Tabeshpour J, Mirzaei S, Golmakaniyoon S, Tayarani-Najaran Z, Ghasemi A, Ghodsi R.
    Arch Pharm (Weinheim); 2019 Jun 10; 352(6):e1800307. PubMed ID: 31012156
    [Abstract] [Full Text] [Related]

  • 6. The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site.
    Boichuk S, Galembikova A, Syuzov K, Dunaev P, Bikinieva F, Aukhadieva A, Zykova S, Igidov N, Gankova K, Novikova M, Kopnin P.
    Molecules; 2021 Sep 24; 26(19):. PubMed ID: 34641324
    [Abstract] [Full Text] [Related]

  • 7. Effects on tubulin polymerization and down-regulation of c-Myc, hTERT and VEGF genes by colchicine haloacetyl and haloaroyl derivatives.
    Marzo-Mas A, Falomir E, Murga J, Carda M, Marco JA.
    Eur J Med Chem; 2018 Apr 25; 150():591-600. PubMed ID: 29550732
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis, biological evaluation, and molecular docking of new benzofuran and indole derivatives as tubulin polymerization inhibitors.
    El-Sayed NF, El-Hussieny M, Ewies EF, El Shehry MF, Awad HM, Fouad MA.
    Drug Dev Res; 2022 Apr 25; 83(2):485-500. PubMed ID: 34523738
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of 1,2,3-triazole linked aminocombretastatin conjugates as mitochondrial mediated apoptosis inducers.
    Kamal A, Shaik B, Nayak VL, Nagaraju B, Kapure JS, Shaheer Malik M, Shaik TB, Prasad B.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5155-67. PubMed ID: 25192811
    [Abstract] [Full Text] [Related]

  • 11. Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway.
    Song J, Wang SH, Song CH, Zhang WX, Zhu JX, Tian XY, Fu XJ, Xu Y, Jin CY, Zhang SY.
    Eur J Med Chem; 2022 Oct 05; 240():114583. PubMed ID: 35834904
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
    Kamal A, Srinivasa Reddy T, Polepalli S, Shalini N, Reddy VG, Subba Rao AV, Jain N, Shankaraiah N.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5466-75. PubMed ID: 25131956
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of novel shikonin-benzo[b]furan derivatives as tubulin polymerization inhibitors targeting the colchicine binding site.
    Shao YY, Yin Y, Lian BP, Leng JF, Xia YZ, Kong LY.
    Eur J Med Chem; 2020 Mar 15; 190():112105. PubMed ID: 32035399
    [Abstract] [Full Text] [Related]

  • 15. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY, Yang MF, Chang CY, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Oct 19; 49(21):6412-5. PubMed ID: 17034147
    [Abstract] [Full Text] [Related]

  • 16. Sulfamic acid promoted one-pot synthesis of phenanthrene fused-dihydrodibenzo-quinolinones: Anticancer activity, tubulin polymerization inhibition and apoptosis inducing studies.
    Kumar NP, Thatikonda S, Tokala R, Kumari SS, Lakshmi UJ, Godugu C, Shankaraiah N, Kamal A.
    Bioorg Med Chem; 2018 May 01; 26(8):1996-2008. PubMed ID: 29525336
    [Abstract] [Full Text] [Related]

  • 17. Discovery of novel N-benzylarylamide-dithiocarbamate based derivatives as dual inhibitors of tubulin polymerization and LSD1 that inhibit gastric cancers.
    Yuan XY, Song CH, Liu XJ, Wang X, Jia MQ, Wang W, Liu WB, Fu XJ, Jin CY, Song J, Zhang SY.
    Eur J Med Chem; 2023 Apr 05; 252():115281. PubMed ID: 36940611
    [Abstract] [Full Text] [Related]

  • 18. New N,C-Diaryl-1,2,4-triazol-3-ones: Synthesis and Evaluation as Anticancer Agents.
    María DS, Claramunt RM, Elguero J, Carda M, Falomir E, Martín-Beltrán C.
    Med Chem; 2019 Apr 05; 15(4):360-372. PubMed ID: 30129416
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells.
    Batran RZ, Kassem AF, Abbas EMH, Elseginy SA, Mounier MM.
    Bioorg Med Chem; 2018 Jul 23; 26(12):3474-3490. PubMed ID: 29793751
    [Abstract] [Full Text] [Related]

  • 20. Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors.
    Sana S, Tokala R, Bajaj DM, Nagesh N, Bokara KK, Kiranmai G, Lakshmi UJ, Vadlamani S, Talla V, Shankaraiah N.
    Bioorg Chem; 2019 Dec 23; 93():103317. PubMed ID: 31586714
    [Abstract] [Full Text] [Related]

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