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Journal Abstract Search

127 related items for PubMed ID: 33246011

  • 1. βB2 W151R mutant is prone to degradation, aggregation and exposes the hydrophobic side chains in the fourth Greek Key motif.
    Xu J, Wang H, Wang A, Xu J, Fu C, Jia Z, Yao K, Chen X.
    Biochim Biophys Acta Mol Basis Dis; 2021 Feb 01; 1867(2):166018. PubMed ID: 33246011
    [Abstract] [Full Text] [Related]

  • 2. A missense mutation in CRYBB2 leads to progressive congenital membranous cataract by impacting the solubility and function of βB2-crystallin.
    Chen W, Chen X, Hu Z, Lin H, Zhou F, Luo L, Zhang X, Zhong X, Yang Y, Wu C, Lin Z, Ye S, Liu Y, Study Group of CCPMOH.
    PLoS One; 2013 Feb 01; 8(11):e81290. PubMed ID: 24312286
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  • 3. Lanosterol reverses protein aggregation in cataracts.
    Zhao L, Chen XJ, Zhu J, Xi YB, Yang X, Hu LD, Ouyang H, Patel SH, Jin X, Lin D, Wu F, Flagg K, Cai H, Li G, Cao G, Lin Y, Chen D, Wen C, Chung C, Wang Y, Qiu A, Yeh E, Wang W, Hu X, Grob S, Abagyan R, Su Z, Tjondro HC, Zhao XJ, Luo H, Hou R, Jefferson J, Perry P, Gao W, Kozak I, Granet D, Li Y, Sun X, Wang J, Zhang L, Liu Y, Yan YB, Zhang K.
    Nature; 2015 Jul 30; 523(7562):607-11. PubMed ID: 26200341
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  • 4. The importance of the last strand at the C-terminus in βB2-crystallin stability and assembly.
    Zhang K, Zhao WJ, Leng XY, Wang S, Yao K, Yan YB.
    Biochim Biophys Acta; 2014 Jan 30; 1842(1):44-55. PubMed ID: 24120835
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  • 8. BetaB2-crystallin mutations associated with cataract and glaucoma leads to mitochondrial alterations in lens epithelial cells and retinal neurons.
    Dulle JE, Rübsam A, Garnai SJ, Pawar HS, Fort PE.
    Exp Eye Res; 2017 Feb 30; 155():85-90. PubMed ID: 28131617
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  • 9. Introduction of an extra tryptophan fluorophore by cataract-associating mutations destabilizes βB2-crystallin and promotes aggregation.
    Xu J, Zhao WJ, Chen XJ, Yao K, Yan YB.
    Biochem Biophys Res Commun; 2018 Oct 12; 504(4):851-856. PubMed ID: 30219234
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  • 10. A novel mutation in CRYBB1 associated with congenital cataract-microcornea syndrome: the p.Ser129Arg mutation destabilizes the βB1/βA3-crystallin heteromer but not the βB1-crystallin homomer.
    Wang KJ, Wang S, Cao NQ, Yan YB, Zhu SQ.
    Hum Mutat; 2011 Mar 12; 32(3):E2050-60. PubMed ID: 21972112
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  • 11. Effects of cataract-causing mutations W59C and W151C on βB2-crystallin structure, stability and folding.
    Zhao WJ, Xu J, Chen XJ, Liu HH, Yao K, Yan YB.
    Int J Biol Macromol; 2017 Oct 12; 103():764-770. PubMed ID: 28528950
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  • 12. The importance of the fourth Greek key motif of human γD-crystallin in maintaining lens transparency-the tale told by the tail.
    Vendra V, Thangapandian M.
    Mol Vis; 2024 Oct 12; 30():37-48. PubMed ID: 38586607
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  • 13. Rapid purification of recombinant betaB2-crystallin using hydrophobic interaction chromatography.
    Jobby MK, Sharma Y.
    Protein Expr Purif; 2003 Mar 12; 28(1):158-64. PubMed ID: 12651120
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  • 17. Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
    Yang X, Chen XJ, Yang Z, Xi YB, Wang L, Wu Y, Yan YB, Rao Y.
    J Med Chem; 2018 Oct 11; 61(19):8693-8706. PubMed ID: 30153006
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  • 19. Targeted knockout of the mouse betaB2-crystallin gene (Crybb2) induces age-related cataract.
    Zhang J, Li J, Huang C, Xue L, Peng Y, Fu Q, Gao L, Zhang J, Li W.
    Invest Ophthalmol Vis Sci; 2008 Dec 11; 49(12):5476-83. PubMed ID: 18719080
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  • 20. Truncation mutations of CRYGD gene in congenital cataracts cause protein aggregation by disrupting the structural stability of γD-crystallin.
    Lin N, Song H, Zhang Y, Chen F, Xu J, Wu W, Tian Q, Luo C, Yao K, Hu L, Chen X.
    Int J Biol Macromol; 2024 Oct 11; 277(Pt 2):134292. PubMed ID: 39084439
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