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Journal Abstract Search

258 related items for PubMed ID: 33248713

  • 1. Novel urea linked ciprofloxacin-chalcone hybrids having antiproliferative topoisomerases I/II inhibitory activities and caspases-mediated apoptosis.
    Mohammed HHH, Abbas SH, Hayallah AM, Abuo-Rahma GEA, Mostafa YA.
    Bioorg Chem; 2021 Jan; 106():104422. PubMed ID: 33248713
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  • 2. Novel nalidixic acid derivatives targeting topoisomerase II enzyme; Design, synthesis, anticancer activity and effect on cell cycle profile.
    Khalil OM, Gedawy EM, El-Malah AA, Adly ME.
    Bioorg Chem; 2019 Mar; 83():262-276. PubMed ID: 30391699
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  • 3. 3,7-bis-benzylidene hydrazide ciprofloxacin derivatives as promising antiproliferative dual TOP I & TOP II isomerases inhibitors.
    Samir M, Ramadan M, Abdelrahman MH, Abdelbaset MS, Abourehab MAS, Abdel-Aziz M, Abuo-Rahma GEA.
    Bioorg Chem; 2021 May; 110():104698. PubMed ID: 33676043
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  • 6. New 1,2,3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization.
    Mohammed HHH, Abd El-Hafeez AA, Ebeid K, Mekkawy AI, Abourehab MAS, Wafa EI, Alhaj-Suliman SO, Salem AK, Ghosh P, Abuo-Rahma GEA, Hayallah AM, Abbas SH.
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):1346-1363. PubMed ID: 35548854
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  • 7. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE, Gedawy EM.
    Eur J Med Chem; 2018 Apr 25; 150():403-418. PubMed ID: 29547830
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  • 9. Synthesis, anticancer evaluation and molecular docking studies of new heterocycles linked to sulfonamide moiety as novel human topoisomerase types I and II poisons.
    Halawa AH, Elgammal WE, Hassan SM, Hassan AH, Nassar HS, Ebrahim HY, Mehany ABM, El-Agrody AM.
    Bioorg Chem; 2020 May 25; 98():103725. PubMed ID: 32199303
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  • 10. Design, synthesis and QSAR study of 2'-hydroxy-4'-alkoxy chalcone derivatives that exert cytotoxic activity by the mitochondrial apoptotic pathway.
    Marquina S, Maldonado-Santiago M, Sánchez-Carranza JN, Antúnez-Mojica M, González-Maya L, Razo-Hernández RS, Alvarez L.
    Bioorg Med Chem; 2019 Jan 01; 27(1):43-54. PubMed ID: 30482548
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  • 11. Design, synthesis and mechanistic study of N-4-Piperazinyl Butyryl Thiazolidinedione derivatives of ciprofloxacin with Anticancer Activity via Topoisomerase I/II inhibition.
    Aziz HA, El-Saghier AM, Badr M, Elsadek BEM, Abuo-Rahma GEA, Shoman ME.
    Sci Rep; 2024 Oct 15; 14(1):24101. PubMed ID: 39406816
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  • 12. Microwave synthesis of novel halogenated β-enaminonitriles linked 9-bromo-1H-benzo[f]chromene moieties: Induces cell cycle arrest and apoptosis in human cancer cells via dual inhibition of topoisomerase I and II.
    Fouda AM, Assiri MA, Mora A, Ali TE, Afifi TH, El-Agrody AM.
    Bioorg Chem; 2019 Dec 15; 93():103289. PubMed ID: 31586716
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  • 13. Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors.
    El-Helby AA, Sakr H, Ayyad RR, Mahdy HA, Khalifa MM, Belal A, Rashed M, El-Sharkawy A, Metwaly AM, Elhendawy MA, Radwan MM, ElSohly MA, Eissa IH.
    Bioorg Chem; 2020 Oct 15; 103():104233. PubMed ID: 32882440
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  • 16. Synthesis and topoisomerases inhibitory activity of heteroaromatic chalcones.
    Jeon KH, Yu HB, Kwak SY, Kwon Y, Na Y.
    Bioorg Med Chem; 2016 Nov 15; 24(22):5921-5928. PubMed ID: 27707625
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  • 18. Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors.
    Eissa IH, Metwaly AM, Belal A, Mehany ABM, Ayyad RR, El-Adl K, Mahdy HA, Taghour MS, El-Gamal KMA, El-Sawah ME, Elmetwally SA, Elhendawy MA, Radwan MM, ElSohly MA.
    Arch Pharm (Weinheim); 2019 Nov 15; 352(11):e1900123. PubMed ID: 31463953
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  • 19. A Novel Camptothecin Derivative 3j Inhibits Nsclc Proliferation Via Induction of Cell Cycle Arrest By Topo I-Mediated DNA Damage.
    Liu Y, Zhang J, Feng S, Zhao T, Li Z, Wang L, Wang P, Du H, Yuan S, Sun L.
    Anticancer Agents Med Chem; 2019 Nov 15; 19(3):365-374. PubMed ID: 30523769
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