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Journal Abstract Search

371 related items for PubMed ID: 33273017

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  • 6. Molecular Basis of Class A β-Lactamase Inhibition by Relebactam.
    Tooke CL, Hinchliffe P, Lang PA, Mulholland AJ, Brem J, Schofield CJ, Spencer J.
    Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31383664
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  • 7. Tautomer-Specific Deacylation and Ω-Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC-2 β-Lactamase.
    Tooke CL, Hinchliffe P, Beer M, Zinovjev K, Colenso CK, Schofield CJ, Mulholland AJ, Spencer J.
    J Am Chem Soc; 2023 Apr 05; 145(13):7166-7180. PubMed ID: 36972204
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  • 8. Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae.
    Yigit H, Queenan AM, Anderson GJ, Domenech-Sanchez A, Biddle JW, Steward CD, Alberti S, Bush K, Tenover FC.
    Antimicrob Agents Chemother; 2001 Apr 05; 45(4):1151-61. PubMed ID: 11257029
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  • 9. Klebsiella pneumoniae Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering.
    Barnes MD, Winkler ML, Taracila MA, Page MG, Desarbre E, Kreiswirth BN, Shields RK, Nguyen MH, Clancy C, Spellberg B, Papp-Wallace KM, Bonomo RA.
    mBio; 2017 Oct 31; 8(5):. PubMed ID: 29089425
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  • 10. The basis for carbapenem hydrolysis by class A β-lactamases: a combined investigation using crystallography and simulations.
    Fonseca F, Chudyk EI, van der Kamp MW, Correia A, Mulholland AJ, Spencer J.
    J Am Chem Soc; 2012 Nov 07; 134(44):18275-85. PubMed ID: 23030300
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  • 11. Crystal structures of KPC-2 β-lactamase in complex with 3-nitrophenyl boronic acid and the penam sulfone PSR-3-226.
    Ke W, Bethel CR, Papp-Wallace KM, Pagadala SR, Nottingham M, Fernandez D, Buynak JD, Bonomo RA, van den Akker F.
    Antimicrob Agents Chemother; 2012 May 07; 56(5):2713-8. PubMed ID: 22330909
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  • 12. Active-Site Plasticity Is Essential to Carbapenem Hydrolysis by OXA-58 Class D β-Lactamase of Acinetobacter baumannii.
    Pratap S, Katiki M, Gill P, Kumar P, Golemi-Kotra D.
    Antimicrob Agents Chemother; 2016 Jan 07; 60(1):75-86. PubMed ID: 26459904
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  • 13. Structural and biochemical evidence that a TEM-1 beta-lactamase N170G active site mutant acts via substrate-assisted catalysis.
    Brown NG, Shanker S, Prasad BV, Palzkill T.
    J Biol Chem; 2009 Nov 27; 284(48):33703-12. PubMed ID: 19812041
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  • 14. Cyclic Boronates Inhibit All Classes of β-Lactamases.
    Cahill ST, Cain R, Wang DY, Lohans CT, Wareham DW, Oswin HP, Mohammed J, Spencer J, Fishwick CW, McDonough MA, Schofield CJ, Brem J.
    Antimicrob Agents Chemother; 2017 Apr 27; 61(4):. PubMed ID: 28115348
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  • 15. Characterization of the First OXA-10 Natural Variant with Increased Carbapenemase Activity.
    Kotsakis SD, Flach CF, Razavi M, Larsson DGJ.
    Antimicrob Agents Chemother; 2019 Jan 27; 63(1):. PubMed ID: 30397053
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  • 16. Structural Basis for Substrate Specificity and Carbapenemase Activity of OXA-48 Class D β-Lactamase.
    Akhtar A, Pemberton OA, Chen Y.
    ACS Infect Dis; 2020 Feb 14; 6(2):261-271. PubMed ID: 31872762
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  • 17. Understanding the molecular determinants of substrate and inhibitor specificities in the Carbapenemase KPC-2: exploring the roles of Arg220 and Glu276.
    Papp-Wallace KM, Taracila MA, Smith KM, Xu Y, Bonomo RA.
    Antimicrob Agents Chemother; 2012 Aug 14; 56(8):4428-38. PubMed ID: 22687511
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  • 18. Biochemical Characterization of VIM-39, a VIM-1-Like Metallo-β-Lactamase Variant from a Multidrug-Resistant Klebsiella pneumoniae Isolate from Greece.
    Papagiannitsis CC, Pollini S, De Luca F, Rossolini GM, Docquier JD, Hrabák J.
    Antimicrob Agents Chemother; 2015 Dec 14; 59(12):7811-4. PubMed ID: 26369975
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  • 19. Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France.
    Petrella S, Ziental-Gelus N, Mayer C, Renard M, Jarlier V, Sougakoff W.
    Antimicrob Agents Chemother; 2008 Oct 14; 52(10):3725-36. PubMed ID: 18625772
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  • 20. Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital.
    Cai JC, Zhou HW, Zhang R, Chen GX.
    Antimicrob Agents Chemother; 2008 Jun 14; 52(6):2014-8. PubMed ID: 18332176
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