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Journal Abstract Search

507 related items for PubMed ID: 33275888

  • 1. The Oncogenic Helicase ALC1 Regulates PARP Inhibitor Potency by Trapping PARP2 at DNA Breaks.
    Blessing C, Mandemaker IK, Gonzalez-Leal C, Preisser J, Schomburg A, Ladurner AG.
    Mol Cell; 2020 Dec 03; 80(5):862-875.e6. PubMed ID: 33275888
    [Abstract] [Full Text] [Related]

  • 2. ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair.
    Tsuda M, Cho K, Ooka M, Shimizu N, Watanabe R, Yasui A, Nakazawa Y, Ogi T, Harada H, Agama K, Nakamura J, Asada R, Fujiike H, Sakuma T, Yamamoto T, Murai J, Hiraoka M, Koike K, Pommier Y, Takeda S, Hirota K.
    PLoS One; 2017 Dec 03; 12(11):e0188320. PubMed ID: 29149203
    [Abstract] [Full Text] [Related]

  • 3. Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome.
    Bacic L, Gaullier G, Sabantsev A, Lehmann LC, Brackmann K, Dimakou D, Halic M, Hewitt G, Boulton SJ, Deindl S.
    Elife; 2021 Sep 06; 10():. PubMed ID: 34486521
    [Abstract] [Full Text] [Related]

  • 4. The chromatin remodeler ALC1 underlies resistance to PARP inhibitor treatment.
    Juhász S, Smith R, Schauer T, Spekhardt D, Mamar H, Zentout S, Chapuis C, Huet S, Timinszky G.
    Sci Adv; 2020 Dec 06; 6(51):. PubMed ID: 33355125
    [Abstract] [Full Text] [Related]

  • 5. A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene.
    Singh HR, Nardozza AP, Möller IR, Knobloch G, Kistemaker HAV, Hassler M, Harrer N, Blessing C, Eustermann S, Kotthoff C, Huet S, Mueller-Planitz F, Filippov DV, Timinszky G, Rand KD, Ladurner AG.
    Mol Cell; 2017 Dec 07; 68(5):860-871.e7. PubMed ID: 29220653
    [Abstract] [Full Text] [Related]

  • 6. Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.
    Hewitt G, Borel V, Segura-Bayona S, Takaki T, Ruis P, Bellelli R, Lehmann LC, Sommerova L, Vancevska A, Tomas-Loba A, Zhu K, Cooper C, Fugger K, Patel H, Goldstone R, Schneider-Luftman D, Herbert E, Stamp G, Brough R, Pettitt S, Lord CJ, West SC, Ahel I, Ahel D, Chapman JR, Deindl S, Boulton SJ.
    Mol Cell; 2021 Feb 18; 81(4):767-783.e11. PubMed ID: 33333017
    [Abstract] [Full Text] [Related]

  • 7. Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein.
    Kulkarni A, Oza J, Yao M, Sohail H, Ginjala V, Tomas-Loba A, Horejsi Z, Tan AR, Boulton SJ, Ganesan S.
    J Biol Chem; 2013 Nov 08; 288(45):32357-32369. PubMed ID: 23926104
    [Abstract] [Full Text] [Related]

  • 8. Chromatin remodeler ALC1 prevents replication-fork collapse by slowing fork progression.
    Ooka M, Abe T, Cho K, Koike K, Takeda S, Hirota K.
    PLoS One; 2018 Nov 08; 13(2):e0192421. PubMed ID: 29408941
    [Abstract] [Full Text] [Related]

  • 9. Poly(ADP‑ribose) polymerase 1/2 inhibitors decrease the ubiquitination of ALC1 mediated by CHFR in breast cancer.
    Wang Y, Wang Y, Wang N, You L, Long F, Shao C, Wang Y, Wu J.
    Oncol Rep; 2019 Oct 08; 42(4):1467-1474. PubMed ID: 31322269
    [Abstract] [Full Text] [Related]

  • 10. Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways.
    Ghosh R, Roy S, Kamyab J, Danzter F, Franco S.
    DNA Repair (Amst); 2016 Sep 08; 45():56-62. PubMed ID: 27373144
    [Abstract] [Full Text] [Related]

  • 11. Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate.
    Gottschalk AJ, Trivedi RD, Conaway JW, Conaway RC.
    J Biol Chem; 2012 Dec 21; 287(52):43527-32. PubMed ID: 23132853
    [Abstract] [Full Text] [Related]

  • 12. ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination-deficient cells.
    Verma P, Zhou Y, Cao Z, Deraska PV, Deb M, Arai E, Li W, Shao Y, Puentes L, Li Y, Patankar S, Mach RH, Faryabi RB, Shi J, Greenberg RA.
    Nat Cell Biol; 2021 Feb 21; 23(2):160-171. PubMed ID: 33462394
    [Abstract] [Full Text] [Related]

  • 13. A Single-Molecule Atomic Force Microscopy Study of PARP1 and PARP2 Recognition of Base Excision Repair DNA Intermediates.
    Sukhanova MV, Hamon L, Kutuzov MM, Joshi V, Abrakhi S, Dobra I, Curmi PA, Pastre D, Lavrik OI.
    J Mol Biol; 2019 Jul 12; 431(15):2655-2673. PubMed ID: 31129062
    [Abstract] [Full Text] [Related]

  • 14. Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1.
    Ahel D, Horejsí Z, Wiechens N, Polo SE, Garcia-Wilson E, Ahel I, Flynn H, Skehel M, West SC, Jackson SP, Owen-Hughes T, Boulton SJ.
    Science; 2009 Sep 04; 325(5945):1240-3. PubMed ID: 19661379
    [Abstract] [Full Text] [Related]

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  • 16. Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1.
    Lehmann LC, Hewitt G, Aibara S, Leitner A, Marklund E, Maslen SL, Maturi V, Chen Y, van der Spoel D, Skehel JM, Moustakas A, Boulton SJ, Deindl S.
    Mol Cell; 2017 Dec 07; 68(5):847-859.e7. PubMed ID: 29220652
    [Abstract] [Full Text] [Related]

  • 17. PARP1-SNAI2 transcription axis drives resistance to PARP inhibitor, Talazoparib.
    Ding X, Zhu Z, Lapek J, McMillan EA, Zhang A, Chung CY, Dubbury S, Lapira J, Firdaus S, Kang X, Gao J, Oyer J, Chionis J, Rollins RA, Li L, Niessen S, Bagrodia S, Zhang L, VanArsdale T.
    Sci Rep; 2022 Jul 21; 12(1):12501. PubMed ID: 35864202
    [Abstract] [Full Text] [Related]

  • 18. Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling.
    Ooi SK, Sato S, Tomomori-Sato C, Zhang Y, Wen Z, Banks CAS, Washburn MP, Unruh JR, Florens L, Conaway RC, Conaway JW.
    Proc Natl Acad Sci U S A; 2021 Sep 07; 118(36):. PubMed ID: 34465625
    [Abstract] [Full Text] [Related]

  • 19. The dynamics and regulation of PARP1 and PARP2 in response to DNA damage and during replication.
    Zhang H, Zha S.
    DNA Repair (Amst); 2024 Aug 07; 140():103690. PubMed ID: 38823186
    [Abstract] [Full Text] [Related]

  • 20. Serine-linked PARP1 auto-modification controls PARP inhibitor response.
    Prokhorova E, Zobel F, Smith R, Zentout S, Gibbs-Seymour I, Schützenhofer K, Peters A, Groslambert J, Zorzini V, Agnew T, Brognard J, Nielsen ML, Ahel D, Huet S, Suskiewicz MJ, Ahel I.
    Nat Commun; 2021 Jul 01; 12(1):4055. PubMed ID: 34210965
    [Abstract] [Full Text] [Related]

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