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Journal Abstract Search

413 related items for PubMed ID: 33309661

  • 1. Ritonavir may inhibit exoribonuclease activity of nsp14 from the SARS-CoV-2 virus and potentiate the activity of chain terminating drugs.
    Narayanan N, Nair DT.
    Int J Biol Macromol; 2021 Jan 31; 168():272-278. PubMed ID: 33309661
    [Abstract] [Full Text] [Related]

  • 2. New targets for drug design: importance of nsp14/nsp10 complex formation for the 3'-5' exoribonucleolytic activity on SARS-CoV-2.
    Saramago M, Bárria C, Costa VG, Souza CS, Viegas SC, Domingues S, Lousa D, Soares CM, Arraiano CM, Matos RG.
    FEBS J; 2021 Sep 31; 288(17):5130-5147. PubMed ID: 33705595
    [Abstract] [Full Text] [Related]

  • 3. Characterization of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification.
    Baddock HT, Brolih S, Yosaatmadja Y, Ratnaweera M, Bielinski M, Swift LP, Cruz-Migoni A, Fan H, Keown JR, Walker AP, Morris GM, Grimes JM, Fodor E, Schofield CJ, Gileadi O, McHugh PJ.
    Nucleic Acids Res; 2022 Feb 22; 50(3):1484-1500. PubMed ID: 35037045
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  • 4. Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN.
    Moeller NH, Shi K, Demir Ö, Belica C, Banerjee S, Yin L, Durfee C, Amaro RE, Aihara H.
    Proc Natl Acad Sci U S A; 2022 Mar 01; 119(9):. PubMed ID: 35165203
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  • 5. Activation of the SARS-CoV-2 NSP14 3'-5' exoribonuclease by NSP10 and response to antiviral inhibitors.
    Riccio AA, Sullivan ED, Copeland WC.
    J Biol Chem; 2022 Jan 01; 298(1):101518. PubMed ID: 34942146
    [Abstract] [Full Text] [Related]

  • 6. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease.
    Canal B, McClure AW, Curran JF, Wu M, Ulferts R, Weissmann F, Zeng J, Bertolin AP, Milligan JC, Basu S, Drury LS, Deegan TD, Fujisawa R, Roberts EL, Basier C, Labib K, Beale R, Howell M, Diffley JFX.
    Biochem J; 2021 Jul 16; 478(13):2445-2464. PubMed ID: 34198326
    [Abstract] [Full Text] [Related]

  • 7. Label-Free Screening of SARS-CoV-2 NSP14 Exonuclease Activity Using SAMDI Mass Spectrometry.
    Scholle MD, Liu C, Deval J, Gurard-Levin ZA.
    SLAS Discov; 2021 Jul 16; 26(6):766-774. PubMed ID: 33870746
    [Abstract] [Full Text] [Related]

  • 8. Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-ExoN domain reveals an exoribonuclease with both structural and functional integrity.
    Lin S, Chen H, Chen Z, Yang F, Ye F, Zheng Y, Yang J, Lin X, Sun H, Wang L, Wen A, Dong H, Xiao Q, Deng D, Cao Y, Lu G.
    Nucleic Acids Res; 2021 May 21; 49(9):5382-5392. PubMed ID: 33956156
    [Abstract] [Full Text] [Related]

  • 9. Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry.
    Pearson LA, Green CJ, Lin D, Petit AP, Gray DW, Cowling VH, Fordyce EAF.
    SLAS Discov; 2021 Jul 21; 26(6):749-756. PubMed ID: 33724070
    [Abstract] [Full Text] [Related]

  • 10. Utilization of the EpiMed Coronabank Chemical Collection to identify potential SARS-CoV-2 antivirals: in silico studies targeting the nsp14 ExoN domain and PLpro naphthalene binding site.
    Liang JJ, Pitsillou E, Lau HLY, Mccubbery CP, Gan H, Hung A, Karagiannis TC.
    J Mol Graph Model; 2024 Sep 21; 131():108803. PubMed ID: 38815531
    [Abstract] [Full Text] [Related]

  • 11. The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2.
    Ogando NS, Zevenhoven-Dobbe JC, van der Meer Y, Bredenbeek PJ, Posthuma CC, Snijder EJ.
    J Virol; 2020 Nov 09; 94(23):. PubMed ID: 32938769
    [Abstract] [Full Text] [Related]

  • 12. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase.
    Basu S, Mak T, Ulferts R, Wu M, Deegan T, Fujisawa R, Tan KW, Lim CT, Basier C, Canal B, Curran JF, Drury LS, McClure AW, Roberts EL, Weissmann F, Zeisner TU, Beale R, Cowling VH, Howell M, Labib K, Diffley JFX.
    Biochem J; 2021 Jul 16; 478(13):2481-2497. PubMed ID: 34198328
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  • 15. Vitamin B12 may inhibit RNA-dependent-RNA polymerase activity of nsp12 from the SARS-CoV-2 virus.
    Narayanan N, Nair DT.
    IUBMB Life; 2020 Oct 16; 72(10):2112-2120. PubMed ID: 32812340
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  • 16. Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication.
    Asthana A, Corona A, Shin WJ, Kwak MJ, Gaughan C, Tramontano E, Jung JU, Schobert R, Jha BK, Silverman RH, Biersack B.
    Viruses; 2023 Jul 13; 15(7):. PubMed ID: 37515225
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