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284 related items for PubMed ID: 33309718
1. VHL gene methylation contributes to excessive erythrocytosis in chronic mountain sickness rat model by upregulating the HIF-2α/EPO pathway. Yang M, Zhu M, Song K, Wuren T, Yan J, Ge RL, Ji L, Cui S. Life Sci; 2021 Feb 01; 266():118873. PubMed ID: 33309718 [Abstract] [Full Text] [Related]
2. The relationship of erythropoietin overexpression with von Hippel-Lindau tumour suppressor gene mutations between hypoxia-inducible factor-1α and -2α in sporadic clear cell renal carcinoma. Gong K, Zhang N, Zhang K, Na Y. Int J Mol Med; 2010 Dec 01; 26(6):907-12. PubMed ID: 21042786 [Abstract] [Full Text] [Related]
3. The Local HIF-2α/EPO Pathway in the Bone Marrow is Associated with Excessive Erythrocytosis and the Increase in Bone Marrow Microvessel Density in Chronic Mountain Sickness. Su J, Li Z, Cui S, Ji L, Geng H, Chai K, Ma X, Bai Z, Yang Y, Wuren T, Ge RL, Rondina MT. High Alt Med Biol; 2015 Dec 01; 16(4):318-30. PubMed ID: 26625252 [Abstract] [Full Text] [Related]
4. [The expression of VHL/HIF signaling pathway in the erythroid progenitor cells with chronic mountain sickness]. Liu HH, Su J, Ma J, Li ZQ, Cui S, Ji LH, Geng H, Tang F, Ge RL. Zhonghua Yi Xue Za Zhi; 2019 Sep 10; 99(34):2670-2674. PubMed ID: 31505717 [Abstract] [Full Text] [Related]
5. The HIF pathway and erythrocytosis. Lee FS, Percy MJ. Annu Rev Pathol; 2011 Sep 10; 6():165-92. PubMed ID: 20939709 [Abstract] [Full Text] [Related]
6. von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis. Hickey MM, Lam JC, Bezman NA, Rathmell WK, Simon MC. J Clin Invest; 2007 Dec 10; 117(12):3879-89. PubMed ID: 17992257 [Abstract] [Full Text] [Related]
7. Update on mutations in the HIF: EPO pathway and their role in erythrocytosis. Lappin TR, Lee FS. Blood Rev; 2019 Sep 10; 37():100590. PubMed ID: 31350093 [Abstract] [Full Text] [Related]
8. [Influence of HIF- 2α on the expression of GATA- 1 in bone marrow CD71(+) cell of high altitude polycythemia rat model]. Liu F, Wei W, Ding J, Chen Y, Feng TT, Ji LH, Shi JY. Zhonghua Xue Ye Xue Za Zhi; 2016 Aug 14; 37(8):696-701. PubMed ID: 27587253 [Abstract] [Full Text] [Related]
9. Action of hypoxia-inducible factor in liver and kidney from mice with Pax8-rtTA-based deletion of von Hippel-Lindau protein. Mathia S, Paliege A, Koesters R, Peters H, Neumayer HH, Bachmann S, Rosenberger C. Acta Physiol (Oxf); 2013 Mar 14; 207(3):565-76. PubMed ID: 23384425 [Abstract] [Full Text] [Related]
10. Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases. Ghosh MC, Zhang DL, Ollivierre WH, Noguchi A, Springer DA, Linehan WM, Rouault TA. Blood; 2021 May 06; 137(18):2509-2519. PubMed ID: 33512384 [Abstract] [Full Text] [Related]
11. Erythrocytosis-associated HIF-2alpha mutations demonstrate a critical role for residues C-terminal to the hydroxylacceptor proline. Furlow PW, Percy MJ, Sutherland S, Bierl C, McMullin MF, Master SR, Lappin TR, Lee FS. J Biol Chem; 2009 Apr 03; 284(14):9050-8. PubMed ID: 19208626 [Abstract] [Full Text] [Related]
12. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function. Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH. Oncogene; 2000 Nov 16; 19(48):5435-43. PubMed ID: 11114720 [Abstract] [Full Text] [Related]
13. Iron deficiency modifies gene expression variation induced by augmented hypoxia sensing. Zhang X, Zhang W, Ma SF, Miasniakova G, Sergueeva A, Ammosova T, Xu M, Nekhai S, Nourai M, Wade MS, Prchal JT, Garcia JGN, Machado RF, Gordeuk VR. Blood Cells Mol Dis; 2014 Jan 16; 52(1):35-45. PubMed ID: 23993337 [Abstract] [Full Text] [Related]
14. Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis. Semenza GL. Blood; 2009 Sep 03; 114(10):2015-9. PubMed ID: 19494350 [Abstract] [Full Text] [Related]
15. Beluga whale pVHL enhances HIF-2α activity via inducing HIF-2α proteasomal degradation under hypoxia. Bi J, Hu B, Wang J, Liu X, Zheng J, Wang D, Xiao W. Oncotarget; 2017 Jun 27; 8(26):42272-42287. PubMed ID: 28178687 [Abstract] [Full Text] [Related]
16. Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo. Rankin EB, Biju MP, Liu Q, Unger TL, Rha J, Johnson RS, Simon MC, Keith B, Haase VH. J Clin Invest; 2007 Apr 27; 117(4):1068-77. PubMed ID: 17404621 [Abstract] [Full Text] [Related]
17. Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia. van Rooijen E, Voest EE, Logister I, Korving J, Schwerte T, Schulte-Merker S, Giles RH, van Eeden FJ. Blood; 2009 Jun 18; 113(25):6449-60. PubMed ID: 19304954 [Abstract] [Full Text] [Related]
19. Novel Homozygous Mutation of the Internal Translation Initiation Start Site of VHL is Exclusively Associated with Erythrocytosis: Indications for Distinct Functional Roles of von Hippel-Lindau Tumor Suppressor Isoforms. Bartels M, van der Zalm MM, van Oirschot BA, Lee FS, Giles RH, Kruip MJ, Gitz-Francois JJ, Van Solinge WW, Bierings M, van Wijk R. Hum Mutat; 2015 Nov 18; 36(11):1039-42. PubMed ID: 26224408 [Abstract] [Full Text] [Related]
20. A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia. Frey H, Moreth K, Hsieh LT, Zeng-Brouwers J, Rathkolb B, Fuchs H, Gailus-Durner V, Iozzo RV, de Angelis MH, Schaefer L. Glycoconj J; 2017 Jun 18; 34(3):393-404. PubMed ID: 27600268 [Abstract] [Full Text] [Related] Page: [Next] [New Search]