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Journal Abstract Search

448 related items for PubMed ID: 33322045

  • 1. Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA Viruses.
    Tampere M, Pettke A, Salata C, Wallner O, Koolmeister T, Cazares-Körner A, Visnes T, Hesselman MC, Kunold E, Wiita E, Kalderén C, Lightowler M, Jemth AS, Lehtiö J, Rosenquist Å, Warpman-Berglund U, Helleday T, Mirazimi A, Jafari R, Puumalainen MR.
    Viruses; 2020 Dec 10; 12(12):. PubMed ID: 33322045
    [Abstract] [Full Text] [Related]

  • 2. iPSC screening for drug repurposing identifies anti-RNA virus agents modulating host cell susceptibility.
    Imamura K, Sakurai Y, Enami T, Shibukawa R, Nishi Y, Ohta A, Shu T, Kawaguchi J, Okada S, Hoenen T, Yasuda J, Inoue H.
    FEBS Open Bio; 2021 May 10; 11(5):1452-1464. PubMed ID: 33822489
    [Abstract] [Full Text] [Related]

  • 3. Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2.
    Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, Liu Y, Zou G, Lavillete D, Zhao Z, Wang R, Zhu L, Xiao G, Lan K, Li H, Xu K.
    Protein Cell; 2020 Oct 10; 11(10):723-739. PubMed ID: 32754890
    [Abstract] [Full Text] [Related]

  • 4. Small-molecule probes targeting the viral PPxY-host Nedd4 interface block egress of a broad range of RNA viruses.
    Han Z, Lu J, Liu Y, Davis B, Lee MS, Olson MA, Ruthel G, Freedman BD, Schnell MJ, Wrobel JE, Reitz AB, Harty RN.
    J Virol; 2014 Jul 10; 88(13):7294-306. PubMed ID: 24741084
    [Abstract] [Full Text] [Related]

  • 5. Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.
    Zhang W, Bailey-Elkin BA, Knaap RCM, Khare B, Dalebout TJ, Johnson GG, van Kasteren PB, McLeish NJ, Gu J, He W, Kikkert M, Mark BL, Sidhu SS.
    PLoS Pathog; 2017 May 10; 13(5):e1006372. PubMed ID: 28542609
    [Abstract] [Full Text] [Related]

  • 6. Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry.
    Mazzon M, Ortega-Prieto AM, Imrie D, Luft C, Hess L, Czieso S, Grove J, Skelton JK, Farleigh L, Bugert JJ, Wright E, Temperton N, Angell R, Oxenford S, Jacobs M, Ketteler R, Dorner M, Marsh M.
    Viruses; 2019 Feb 20; 11(2):. PubMed ID: 30791609
    [Abstract] [Full Text] [Related]

  • 7. Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assay.
    Elshabrawy HA, Fan J, Haddad CS, Ratia K, Broder CC, Caffrey M, Prabhakar BS.
    J Virol; 2014 Apr 20; 88(8):4353-65. PubMed ID: 24501399
    [Abstract] [Full Text] [Related]

  • 8. Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway.
    Pattabhi S, Wilkins CR, Dong R, Knoll ML, Posakony J, Kaiser S, Mire CE, Wang ML, Ireton RC, Geisbert TW, Bedard KM, Iadonato SP, Loo YM, Gale M.
    J Virol; 2015 Dec 16; 90(5):2372-87. PubMed ID: 26676770
    [Abstract] [Full Text] [Related]

  • 9. Heat Shock Protein 70 Family Members Interact with Crimean-Congo Hemorrhagic Fever Virus and Hazara Virus Nucleocapsid Proteins and Perform a Functional Role in the Nairovirus Replication Cycle.
    Surtees R, Dowall SD, Shaw A, Armstrong S, Hewson R, Carroll MW, Mankouri J, Edwards TA, Hiscox JA, Barr JN.
    J Virol; 2016 Oct 15; 90(20):9305-16. PubMed ID: 27512070
    [Abstract] [Full Text] [Related]

  • 10. The SKI complex is a broad-spectrum, host-directed antiviral drug target for coronaviruses, influenza, and filoviruses.
    Weston S, Baracco L, Keller C, Matthews K, McGrath ME, Logue J, Liang J, Dyall J, Holbrook MR, Hensley LE, Jahrling PB, Yu W, MacKerell AD, Frieman MB.
    Proc Natl Acad Sci U S A; 2020 Dec 01; 117(48):30687-30698. PubMed ID: 33184176
    [Abstract] [Full Text] [Related]

  • 11. Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.
    Luthra P, Naidoo J, Pietzsch CA, De S, Khadka S, Anantpadma M, Williams CG, Edwards MR, Davey RA, Bukreyev A, Ready JM, Basler CF.
    Antiviral Res; 2018 Oct 01; 158():288-302. PubMed ID: 30144461
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses.
    Mounce BC, Cesaro T, Moratorio G, Hooikaas PJ, Yakovleva A, Werneke SW, Smith EC, Poirier EZ, Simon-Loriere E, Prot M, Tamietti C, Vitry S, Volle R, Khou C, Frenkiel MP, Sakuntabhai A, Delpeyroux F, Pardigon N, Flamand M, Barba-Spaeth G, Lafon M, Denison MR, Albert ML, Vignuzzi M.
    J Virol; 2016 Nov 01; 90(21):9683-9692. PubMed ID: 27535047
    [Abstract] [Full Text] [Related]

  • 13. Antiviral drugs targeting endosomal membrane proteins inhibit distant animal and human pathogenic viruses.
    Galindo I, Garaigorta U, Lasala F, Cuesta-Geijo MA, Bueno P, Gil C, Delgado R, Gastaminza P, Alonso C.
    Antiviral Res; 2021 Feb 01; 186():104990. PubMed ID: 33249093
    [Abstract] [Full Text] [Related]

  • 14. A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replication.
    Luthra P, Liang J, Pietzsch CA, Khadka S, Edwards MR, Wei S, De S, Posner B, Bukreyev A, Ready JM, Basler CF.
    Antiviral Res; 2018 Feb 01; 150():193-201. PubMed ID: 29294299
    [Abstract] [Full Text] [Related]

  • 15. Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir.
    Gordon CJ, Lee HW, Tchesnokov EP, Perry JK, Feng JY, Bilello JP, Porter DP, Götte M.
    J Biol Chem; 2022 Feb 01; 298(2):101529. PubMed ID: 34953856
    [Abstract] [Full Text] [Related]

  • 16. Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses.
    Artese A, Svicher V, Costa G, Salpini R, Di Maio VC, Alkhatib M, Ambrosio FA, Santoro MM, Assaraf YG, Alcaro S, Ceccherini-Silberstein F.
    Drug Resist Updat; 2020 Dec 01; 53():100721. PubMed ID: 33132205
    [Abstract] [Full Text] [Related]

  • 17. Antagonistic antiviral activity between IFN-lambda and IFN-alpha against lethal Crimean-Congo hemorrhagic fever virus in vitro.
    Bordi L, Lalle E, Caglioti C, Travaglini D, Lapa D, Marsella P, Quartu S, Kis Z, Arien KK, Huemer HP, Meschi S, Ippolito G, Di Caro A, Capobianchi MR, Castilletti C.
    PLoS One; 2015 Dec 01; 10(2):e0116816. PubMed ID: 25693189
    [Abstract] [Full Text] [Related]

  • 18. High-content image-based screening of a signal transduction pathway inhibitor small-molecule library against highly pathogenic RNA viruses.
    Mudhasani R, Kota KP, Retterer C, Tran JP, Tritsch SR, Zamani R, Whitehouse CA, Bavari S.
    J Biomol Screen; 2015 Jan 01; 20(1):141-52. PubMed ID: 25342145
    [Abstract] [Full Text] [Related]

  • 19. The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication.
    Bharaj P, Atkins C, Luthra P, Giraldo MI, Dawes BE, Miorin L, Johnson JR, Krogan NJ, Basler CF, Freiberg AN, Rajsbaum R.
    J Virol; 2017 Sep 15; 91(18):. PubMed ID: 28679761
    [Abstract] [Full Text] [Related]

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