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PUBMED FOR HANDHELDS

Journal Abstract Search


176 related items for PubMed ID: 33348757

  • 1. Design, Synthesis and Comprehensive Investigations of Pyrrolo[3,4-d]pyridazinone-Based 1,3,4-Oxadiazole as New Class of Selective COX-2 Inhibitors.
    Szczukowski Ł, Krzyżak E, Zborowska A, Zając P, Potyrak K, Peregrym K, Wiatrak B, Marciniak A, Świątek P.
    Int J Mol Sci; 2020 Dec 17; 21(24):. PubMed ID: 33348757
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, biological evaluation and in silico studies of novel pyrrolo[3,4-d]pyridazinone derivatives withpromising anti-inflammatory and antioxidant activity.
    Szczukowski Ł, Redzicka A, Wiatrak B, Krzyżak E, Marciniak A, Gębczak K, Gębarowski T, Świątek P.
    Bioorg Chem; 2020 Sep 17; 102():104035. PubMed ID: 32721780
    [Abstract] [Full Text] [Related]

  • 3. In Vitro and In Silico Evaluation of New 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]pyridazinone as Promising Cyclooxygenase Inhibitors.
    Peregrym K, Szczukowski Ł, Wiatrak B, Potyrak K, Czyżnikowska Ż, Świątek P.
    Int J Mol Sci; 2021 Aug 24; 22(17):. PubMed ID: 34502040
    [Abstract] [Full Text] [Related]

  • 4. New N-Substituted-1,2,4-triazole Derivatives of Pyrrolo[3,4-d]pyridazinone with Significant Anti-Inflammatory Activity-Design, Synthesis and Complementary In Vitro, Computational and Spectroscopic Studies.
    Szczukowski Ł, Krzyżak E, Wiatrak B, Jawień P, Marciniak A, Kotynia A, Świątek P.
    Int J Mol Sci; 2021 Oct 18; 22(20):. PubMed ID: 34681894
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, Biological, Spectroscopic and Computational Investigations of Novel N-Acylhydrazone Derivatives of Pyrrolo[3,4-d]pyridazinone as Dual COX/LOX Inhibitors.
    Mikus J, Świątek P, Przybyła P, Krzyżak E, Marciniak A, Kotynia A, Redzicka A, Wiatrak B, Jawień P, Gębarowski T, Szczukowski Ł.
    Molecules; 2023 Jul 18; 28(14):. PubMed ID: 37513351
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of pyridazinone derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents.
    Ahmed EM, Kassab AE, El-Malah AA, Hassan MSA.
    Eur J Med Chem; 2019 Jun 01; 171():25-37. PubMed ID: 30904755
    [Abstract] [Full Text] [Related]

  • 7. New pyridazine derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents; design, synthesis and biological evaluation.
    Ahmed EM, Hassan MSA, El-Malah AA, Kassab AE.
    Bioorg Chem; 2020 Jan 01; 95():103497. PubMed ID: 31838289
    [Abstract] [Full Text] [Related]

  • 8. Synthesis of novel of 2, 5-disubstituted 1, 3, 4- oxadiazole derivatives and their in vitro anti-inflammatory, anti-oxidant evaluation, and molecular docking study.
    Kashid BB, Salunkhe PH, Dongare BB, More KR, Khedkar VM, Ghanwat AA.
    Bioorg Med Chem Lett; 2020 Jun 15; 30(12):127136. PubMed ID: 32280025
    [Abstract] [Full Text] [Related]

  • 9. COX-1/COX-2 inhibition activities and molecular docking study of newly designed and synthesized pyrrolo[3,4-c]pyrrole Mannich bases.
    Redzicka A, Szczukowski Ł, Kochel A, Wiatrak B, Gębczak K, Czyżnikowska Ż.
    Bioorg Med Chem; 2019 Sep 01; 27(17):3918-3928. PubMed ID: 31345747
    [Abstract] [Full Text] [Related]

  • 10. New 1,3,4-Oxadiazole Derivatives of Pyridothiazine-1,1-Dioxide with Anti-Inflammatory Activity.
    Glomb T, Wiatrak B, Gębczak K, Gębarowski T, Bodetko D, Czyżnikowska Ż, Świątek P.
    Int J Mol Sci; 2020 Nov 30; 21(23):. PubMed ID: 33266208
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis, modeling studies and biological evaluation of thiazolidine derivatives containing pyrazole core as potential anti-diabetic PPAR-γ agonists and anti-inflammatory COX-2 selective inhibitors.
    Abdellatif KRA, Fadaly WAA, Kamel GM, Elshaier YAMM, El-Magd MA.
    Bioorg Chem; 2019 Feb 30; 82():86-99. PubMed ID: 30278282
    [Abstract] [Full Text] [Related]

  • 12. Design and Synthesis of Novel 1,3,4-Oxadiazole and 1,2,4-Triazole Derivatives as Cyclooxygenase-2 Inhibitors with Anti-inflammatory and Antioxidant activity in LPS-stimulated RAW264.7 Macrophages.
    Hamoud MMS, Osman NA, Rezq S, A A Abd El-Wahab H, E A Hassan A, Abdel-Fattah HA, Romero DG, Ghanim AM.
    Bioorg Chem; 2022 Jul 30; 124():105808. PubMed ID: 35447409
    [Abstract] [Full Text] [Related]

  • 13. Design and synthesis of benzimidazole analogs endowed with oxadiazole as selective COX-2 inhibitor.
    Rathore A, Rahman MU, Siddiqui AA, Ali A, Shaharyar M.
    Arch Pharm (Weinheim); 2014 Dec 30; 347(12):923-35. PubMed ID: 25303727
    [Abstract] [Full Text] [Related]

  • 14. New oxadiazoles with selective-COX-2 and EGFR dual inhibitory activity: Design, synthesis, cytotoxicity evaluation and in silico studies.
    El-Sayed NA, Nour MS, Salem MA, Arafa RK.
    Eur J Med Chem; 2019 Dec 01; 183():111693. PubMed ID: 31539778
    [Abstract] [Full Text] [Related]

  • 15. New Ferrocene Compounds as Selective Cyclooxygenase (COX-2) Inhibitors: Design, Synthesis, Cytotoxicity and Enzyme-inhibitory Activity.
    Farzaneh S, Zeinalzadeh E, Daraei B, Shahhosseini S, Zarghi A.
    Anticancer Agents Med Chem; 2018 Dec 01; 18(2):295-301. PubMed ID: 28971779
    [Abstract] [Full Text] [Related]

  • 16. Green synthesis of therapeutically active 1,3,4-oxadiazoles as antioxidants, selective COX-2 inhibitors and their in silico studies.
    Nesaragi AR, Kamble RR, Dixit S, Kodasi B, Hoolageri SR, Bayannavar PK, Dasappa JP, Vootla S, Joshi SD, Kumbar VM.
    Bioorg Med Chem Lett; 2021 Jul 01; 43():128112. PubMed ID: 33991632
    [Abstract] [Full Text] [Related]

  • 17. Synthesis, COX-2 inhibition, anti-inflammatory activity, molecular docking, and histopathological studies of new pyridazine derivatives.
    Ewieda SY, Hassan RA, Ahmed EM, Abdou AM, Hassan MSA.
    Bioorg Chem; 2024 Sep 01; 150():107623. PubMed ID: 39002251
    [Abstract] [Full Text] [Related]

  • 18. Novel anti-inflammatory agents based on pyridazinone scaffold; design, synthesis and in vivo activity.
    Abouzid K, Bekhit SA.
    Bioorg Med Chem; 2008 May 15; 16(10):5547-56. PubMed ID: 18430576
    [Abstract] [Full Text] [Related]

  • 19. Synthesis of Hybrids of Dihydropyrimidine and Pyridazinone as potential Anti-Breast Cancer Agents.
    Akhtar W, Verma G, Khan MF, Shaquiquzzaman M, Rana A, Anwer T, Akhter M, Alam MM.
    Mini Rev Med Chem; 2018 May 15; 18(4):369-379. PubMed ID: 28486908
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, biological evaluation, and docking analysis of a novel family of 1-methyl-1H-pyrrole-2,5-diones as highly potent and selective cyclooxygenase-2 (COX-2) inhibitors.
    Kim KJ, Choi MJ, Shin JS, Kim M, Choi HE, Kang SM, Jin JH, Lee KT, Lee JY.
    Bioorg Med Chem Lett; 2014 Apr 15; 24(8):1958-62. PubMed ID: 24656662
    [Abstract] [Full Text] [Related]


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