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Journal Abstract Search
119 related items for PubMed ID: 3336016
1. Conformational requirements of substrates for activity with phenylethanolamine N-methyltransferase. Grunewald GL, Ye Q, Kieffer L, Monn JA. J Med Chem; 1988 Jan; 31(1):169-71. PubMed ID: 3336016 [Abstract] [Full Text] [Related]
2. Conformational and steric aspects of phenylethanolamine and phenylethylamine analogues as substrates or inhibitors of phenylethanolamine N-methyltransferase. Grunewald GL, Ye Q, Sall DJ, Criscione KR, Wise B. Mol Pharmacol; 1989 Jan; 35(1):93-7. PubMed ID: 2913486 [Abstract] [Full Text] [Related]
6. Conformational preference for the binding of biaryl substrates and inhibitors to the active site of phenylethanolamine N-methyltransferase. Grunewald GL, Carter AE, Sall DJ, Monn JA. J Med Chem; 1988 Jan; 31(1):60-5. PubMed ID: 3336033 [Abstract] [Full Text] [Related]
8. Inhibition of phenylethanolamine N-methyltransferase (PNMT) by aromatic hydroxy-substituted 1,2,3,4,-tetrahydroisoquinolines: further studies on the hydrophilic pocket of the aromatic ring binding region of the active site. Sall DJ, Grunewald GL. J Med Chem; 1987 Dec; 30(12):2208-16. PubMed ID: 3681890 [Abstract] [Full Text] [Related]
14. 3,7-Disubstituted-1,2,3,4-tetrahydroisoquinolines display remarkable potency and selectivity as inhibitors of phenylethanolamine N-methyltransferase versus the alpha2-adrenoceptor. Grunewald GL, Dahanukar VH, Teoh B, Criscione KR. J Med Chem; 1999 Jun 03; 42(11):1982-90. PubMed ID: 10354406 [Abstract] [Full Text] [Related]
16. Binding requirements of phenolic phenylethylamines in the benzonorbornene skeleton at the active site of phenylethanolamine N-methyltransferase. Grunewald GL, Arrington HS, Bartlett WJ, Reitz TJ, Sall DJ. J Med Chem; 1986 Oct 03; 29(10):1972-82. PubMed ID: 3761316 [Abstract] [Full Text] [Related]
17. Cell-Effective Transition-State Analogue of Phenylethanolamine N-Methyltransferase. Mahmoodi N, Minnow YVT, Harijan RK, Bedard GT, Schramm VL. Biochemistry; 2023 Aug 01; 62(15):2257-2268. PubMed ID: 37467463 [Abstract] [Full Text] [Related]
18. Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity. Drinkwater N, Gee CL, Puri M, Criscione KR, McLeish MJ, Grunewald GL, Martin JL. Biochem J; 2009 Aug 27; 422(3):463-71. PubMed ID: 19570037 [Abstract] [Full Text] [Related]
19. Effects of a 3-alkyl-, 4-hydroxy- and/or 8-aromatic-substituent on the phenylethanolamine N-methyltransferase inhibitor potency and alpha2-adrenoceptor affinity of 2,3,4,5-tetrahydro-1H-2-benzazepines. Grunewald GL, Dahanukar VH, Criscione KR. Bioorg Med Chem; 2001 Aug 27; 9(8):1957-65. PubMed ID: 11504632 [Abstract] [Full Text] [Related]