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433 related items for PubMed ID: 33374819

  • 1. Novel Advances in Modifying BMPR2 Signaling in PAH.
    Dannewitz Prosseda S, Ali MK, Spiekerkoetter E.
    Genes (Basel); 2020 Dec 23; 12(1):. PubMed ID: 33374819
    [Abstract] [Full Text] [Related]

  • 2. FHIT, a Novel Modifier Gene in Pulmonary Arterial Hypertension.
    Dannewitz Prosseda S, Tian X, Kuramoto K, Boehm M, Sudheendra D, Miyagawa K, Zhang F, Solow-Cordero D, Saldivar JC, Austin ED, Loyd JE, Wheeler L, Andruska A, Donato M, Wang L, Huebner K, Metzger RJ, Khatri P, Spiekerkoetter E.
    Am J Respir Crit Care Med; 2019 Jan 01; 199(1):83-98. PubMed ID: 30107138
    [Abstract] [Full Text] [Related]

  • 3. Regulation of the Methylation and Expression Levels of the BMPR2 Gene by SIN3a as a Novel Therapeutic Mechanism in Pulmonary Arterial Hypertension.
    Bisserier M, Mathiyalagan P, Zhang S, Elmastour F, Dorfmüller P, Humbert M, David G, Tarzami S, Weber T, Perros F, Sassi Y, Sahoo S, Hadri L.
    Circulation; 2021 Jul 06; 144(1):52-73. PubMed ID: 34078089
    [Abstract] [Full Text] [Related]

  • 4. The BMP Receptor 2 in Pulmonary Arterial Hypertension: When and Where the Animal Model Matches the Patient.
    Happé C, Kurakula K, Sun XQ, da Silva Goncalves Bos D, Rol N, Guignabert C, Tu L, Schalij I, Wiesmeijer KC, Tura-Ceide O, Vonk Noordegraaf A, de Man FS, Bogaard HJ, Goumans MJ.
    Cells; 2020 Jun 08; 9(6):. PubMed ID: 32521690
    [Abstract] [Full Text] [Related]

  • 5. Phenotypically Silent Bone Morphogenetic Protein Receptor 2 Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing the Risk for Neointimal Transformation.
    Tian W, Jiang X, Sung YK, Shuffle E, Wu TH, Kao PN, Tu AB, Dorfmüller P, Cao A, Wang L, Peng G, Kim Y, Zhang P, Chappell J, Pasupneti S, Dahms P, Maguire P, Chaib H, Zamanian R, Peters-Golden M, Snyder MP, Voelkel NF, Humbert M, Rabinovitch M, Nicolls MR.
    Circulation; 2019 Oct 22; 140(17):1409-1425. PubMed ID: 31462075
    [Abstract] [Full Text] [Related]

  • 6. At the X-Roads of Sex and Genetics in Pulmonary Arterial Hypertension.
    Cirulis MM, Dodson MW, Brown LM, Brown SM, Lahm T, Elliott G.
    Genes (Basel); 2020 Nov 20; 11(11):. PubMed ID: 33233517
    [Abstract] [Full Text] [Related]

  • 7. BMP type II receptor as a therapeutic target in pulmonary arterial hypertension.
    Orriols M, Gomez-Puerto MC, Ten Dijke P.
    Cell Mol Life Sci; 2017 Aug 20; 74(16):2979-2995. PubMed ID: 28447104
    [Abstract] [Full Text] [Related]

  • 8. BMPR2-expressing bone marrow-derived endothelial-like progenitor cells alleviate pulmonary arterial hypertension in vivo.
    Harper RL, Maiolo S, Ward RJ, Seyfang J, Cockshell MP, Bonder CS, Reynolds PN.
    Respirology; 2019 Nov 20; 24(11):1095-1103. PubMed ID: 30977250
    [Abstract] [Full Text] [Related]

  • 9. The Role of Bone Morphogenetic Protein Receptor Type 2 (BMPR2) and the Prospects of Utilizing Induced Pluripotent Stem Cells (iPSCs) in Pulmonary Arterial Hypertension Disease Modeling.
    Devendran A, Kar S, Bailey R, Trivieri MG.
    Cells; 2022 Nov 29; 11(23):. PubMed ID: 36497082
    [Abstract] [Full Text] [Related]

  • 10. Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension.
    Gomez-Puerto MC, van Zuijen I, Huang CJ, Szulcek R, Pan X, van Dinther MA, Kurakula K, Wiesmeijer CC, Goumans MJ, Bogaard HJ, Morrell NW, Rana AA, Ten Dijke P.
    J Pathol; 2019 Nov 29; 249(3):356-367. PubMed ID: 31257577
    [Abstract] [Full Text] [Related]

  • 11. Combination Therapy with STAT3 Inhibitor Enhances SERCA2a-Induced BMPR2 Expression and Inhibits Pulmonary Arterial Hypertension.
    Bisserier M, Katz MG, Bueno-Beti C, Brojakowska A, Zhang S, Gubara S, Kohlbrenner E, Fazal S, Fargnoli A, Dorfmuller P, Humbert M, Hata A, Goukassian DA, Sassi Y, Hadri L.
    Int J Mol Sci; 2021 Aug 24; 22(17):. PubMed ID: 34502015
    [Abstract] [Full Text] [Related]

  • 12. Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension.
    Hautefort A, Mendes-Ferreira P, Sabourin J, Manaud G, Bertero T, Rucker-Martin C, Riou M, Adão R, Manoury B, Lambert M, Boet A, Lecerf F, Domergue V, Brás-Silva C, Gomez AM, Montani D, Girerd B, Humbert M, Antigny F, Perros F.
    Circulation; 2019 Feb 12; 139(7):932-948. PubMed ID: 30586714
    [Abstract] [Full Text] [Related]

  • 13. 4PBA Restores Signaling of a Cysteine-substituted Mutant BMPR2 Receptor Found in Patients with Pulmonary Arterial Hypertension.
    Dunmore BJ, Yang X, Crosby A, Moore S, Long L, Huang C, Southwood M, Austin ED, Rana A, Upton PD, Morrell NW.
    Am J Respir Cell Mol Biol; 2020 Aug 12; 63(2):160-171. PubMed ID: 32255665
    [Abstract] [Full Text] [Related]

  • 14. Significance of BMPR2 mutations in pulmonary arterial hypertension.
    Tatius B, Wasityastuti W, Astarini FD, Nugrahaningsih DAA.
    Respir Investig; 2021 Jul 12; 59(4):397-407. PubMed ID: 34023242
    [Abstract] [Full Text] [Related]

  • 15. CCL5 deficiency rescues pulmonary vascular dysfunction, and reverses pulmonary hypertension via caveolin-1-dependent BMPR2 activation.
    Nie X, Tan J, Dai Y, Liu Y, Zou J, Sun J, Ye S, Shen C, Fan L, Chen J, Bian JS.
    J Mol Cell Cardiol; 2018 Mar 12; 116():41-56. PubMed ID: 29374556
    [Abstract] [Full Text] [Related]

  • 16. BMPR2 Loss Activates AKT by Disrupting DLL4/NOTCH1 and PPARγ Signaling in Pulmonary Arterial Hypertension.
    Awad KS, Wang S, Dougherty EJ, Keshavarz A, Demirkale CY, Yu ZX, Miller L, Elinoff JM, Danner RL.
    Int J Mol Sci; 2024 May 15; 25(10):. PubMed ID: 38791441
    [Abstract] [Full Text] [Related]

  • 17. Impaired Interleukin-15 Signaling via BMPR2 Loss Drives Natural Killer Cell Deficiency and Pulmonary Hypertension.
    Hilton LR, Rätsep MT, VandenBroek MM, Jafri S, Laverty KJ, Mitchell M, Theilmann AL, Smart JA, Hawke LG, Moore SD, Renaud SJ, Soares MJ, Morrell NW, Ormiston ML.
    Hypertension; 2022 Nov 15; 79(11):2493-2504. PubMed ID: 36043416
    [Abstract] [Full Text] [Related]

  • 18. Targeted gene delivery of BMPR2 attenuates pulmonary hypertension.
    Reynolds AM, Holmes MD, Danilov SM, Reynolds PN.
    Eur Respir J; 2012 Feb 15; 39(2):329-43. PubMed ID: 21737550
    [Abstract] [Full Text] [Related]

  • 19. Endothelin-Bone morphogenetic protein type 2 receptor interaction induces pulmonary artery smooth muscle cell hyperplasia in pulmonary arterial hypertension.
    Maruyama H, Dewachter C, Belhaj A, Rondelet B, Sakai S, Remmelink M, Vachiery JL, Naeije R, Dewachter L.
    J Heart Lung Transplant; 2015 Mar 15; 34(3):468-78. PubMed ID: 25447587
    [Abstract] [Full Text] [Related]

  • 20. Single-cell RNA sequencing reveals that BMPR2 mutation regulates right ventricular function via ID genes.
    Du M, Jiang H, Liu H, Zhao X, Zhou Y, Zhou F, Piao C, Xu G, Ma F, Wang J, Perros F, Morrell NW, Gu H, Yang J.
    Eur Respir J; 2022 Jul 15; 60(1):. PubMed ID: 34857612
    [Abstract] [Full Text] [Related]

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