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137 related items for PubMed ID: 33376013

  • 1. QM/MM analysis, synthesis and biological evaluation of epalrestat based mutual-prodrugs for diabetic neuropathy and nephropathy.
    Choudhary S, Kumar M, Silakari O.
    Bioorg Chem; 2021 Mar; 108():104556. PubMed ID: 33376013
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  • 3. hCES1 and hCES2 mediated activation of epalrestat-antioxidant mutual prodrugs: Unwinding the hydrolytic mechanism using in silico approaches.
    Choudhary S, Silakari O.
    J Mol Graph Model; 2019 Sep; 91():148-163. PubMed ID: 31252365
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  • 4. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on progression of diabetic neuropathy and other microvascular complications: multivariate epidemiological analysis based on patient background factors and severity of diabetic neuropathy.
    Hotta N, Kawamori R, Fukuda M, Shigeta Y, Aldose Reductase Inhibitor-Diabetes Complications Trial Study Group.
    Diabet Med; 2012 Dec; 29(12):1529-33. PubMed ID: 22507139
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  • 5. Virtual screening of epalrestat mimicking selective ALR2 inhibitors from natural product database: auto pharmacophore, ADMET prediction and molecular dynamics approach.
    Choudhary S, Silakari O.
    J Biomol Struct Dyn; 2022 Aug; 40(13):6052-6070. PubMed ID: 33480327
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  • 15. Continuous inhibition of excessive polyol pathway flux in peripheral nerves by aldose reductase inhibitor fidarestat leads to improvement of diabetic neuropathy.
    Mizuno K, Kato N, Makino M, Suzuki T, Shindo M.
    J Diabetes Complications; 1999 Aug; 13(3):141-50. PubMed ID: 10509874
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  • 16. Substituted 2-thioxothiazolidin-4-one derivatives showed protective effects against diabetic cataract via inhibition of aldose reductase.
    Huang W, Zhang Y, Liang X, Yang L.
    Arch Pharm (Weinheim); 2020 Jun; 353(6):e1900371. PubMed ID: 32237167
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  • 18. Nephroprotective effect of Combretum micranthum G. Don in nicotinamide-streptozotocin induced diabetic nephropathy in rats: In-vivo and in-silico experiments.
    Kpemissi M, Potârniche AV, Lawson-Evi P, Metowogo K, Melila M, Dramane P, Taulescu M, Chandramohan V, Suhas DS, Puneeth TA, S VK, Vlase L, Andrei S, Eklu-Gadegbeku K, Sevastre B, Veerapur VP.
    J Ethnopharmacol; 2020 Oct 28; 261():113133. PubMed ID: 32673708
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  • 19. Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG.
    Iyer S, Sam FS, DiPrimio N, Preston G, Verheijen J, Murthy K, Parton Z, Tsang H, Lao J, Morava E, Perlstein EO.
    Dis Model Mech; 2019 Nov 11; 12(11):. PubMed ID: 31636082
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  • 20. Pain Allaying Epalrestat-Loaded Lipid Nanoformulation for the Diabetic Neuropathic Pain Interventions: Design, Development, and Animal Study.
    Vishwakarma VK, Paswan SK, Arora T, Verma RK, Yadav HN.
    Curr Drug Metab; 2022 Nov 11; 23(7):571-583. PubMed ID: 35950248
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