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511 related items for PubMed ID: 33382987

  • 1. Spinal motor neuron loss occurs through a p53-and-p21-independent mechanism in the Smn2B/- mouse model of spinal muscular atrophy.
    Reedich EJ, Kalski M, Armijo N, Cox GA, DiDonato CJ.
    Exp Neurol; 2021 Mar; 337():113587. PubMed ID: 33382987
    [Abstract] [Full Text] [Related]

  • 2. Hyperexcitability precedes motoneuron loss in the Smn2B/- mouse model of spinal muscular atrophy.
    Quinlan KA, Reedich EJ, Arnold WD, Puritz AC, Cavarsan CF, Heckman CJ, DiDonato CJ.
    J Neurophysiol; 2019 Oct 01; 122(4):1297-1311. PubMed ID: 31365319
    [Abstract] [Full Text] [Related]

  • 3. Mechanisms of exercise-induced survival motor neuron expression in the skeletal muscle of spinal muscular atrophy-like mice.
    Ng SY, Mikhail A, Ljubicic V.
    J Physiol; 2019 Sep 01; 597(18):4757-4778. PubMed ID: 31361024
    [Abstract] [Full Text] [Related]

  • 4. Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy.
    Bowerman M, Murray LM, Boyer JG, Anderson CL, Kothary R.
    BMC Med; 2012 Mar 07; 10():24. PubMed ID: 22397316
    [Abstract] [Full Text] [Related]

  • 5. Reduced survival of motor neuron (SMN) protein in motor neuronal progenitors functions cell autonomously to cause spinal muscular atrophy in model mice expressing the human centromeric (SMN2) gene.
    Park GH, Maeno-Hikichi Y, Awano T, Landmesser LT, Monani UR.
    J Neurosci; 2010 Sep 08; 30(36):12005-19. PubMed ID: 20826664
    [Abstract] [Full Text] [Related]

  • 6. Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy.
    Martinez TL, Kong L, Wang X, Osborne MA, Crowder ME, Van Meerbeke JP, Xu X, Davis C, Wooley J, Goldhamer DJ, Lutz CM, Rich MM, Sumner CJ.
    J Neurosci; 2012 Jun 20; 32(25):8703-15. PubMed ID: 22723710
    [Abstract] [Full Text] [Related]

  • 7. What Genetics Has Told Us and How It Can Inform Future Experiments for Spinal Muscular Atrophy, a Perspective.
    Blatnik AJ, McGovern VL, Burghes AHM.
    Int J Mol Sci; 2021 Aug 06; 22(16):. PubMed ID: 34445199
    [Abstract] [Full Text] [Related]

  • 8. Calpain Inhibition Increases SMN Protein in Spinal Cord Motoneurons and Ameliorates the Spinal Muscular Atrophy Phenotype in Mice.
    de la Fuente S, Sansa A, Periyakaruppiah A, Garcera A, Soler RM.
    Mol Neurobiol; 2019 Jun 06; 56(6):4414-4427. PubMed ID: 30327977
    [Abstract] [Full Text] [Related]

  • 9. Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model.
    Hua Y, Sahashi K, Rigo F, Hung G, Horev G, Bennett CF, Krainer AR.
    Nature; 2011 Oct 05; 478(7367):123-6. PubMed ID: 21979052
    [Abstract] [Full Text] [Related]

  • 10. Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy.
    Murray LM, Lee S, Bäumer D, Parson SH, Talbot K, Gillingwater TH.
    Hum Mol Genet; 2010 Feb 01; 19(3):420-33. PubMed ID: 19884170
    [Abstract] [Full Text] [Related]

  • 11. The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy.
    Monani UR, Sendtner M, Coovert DD, Parsons DW, Andreassi C, Le TT, Jablonka S, Schrank B, Rossoll W, Prior TW, Morris GE, Burghes AH.
    Hum Mol Genet; 2000 Feb 12; 9(3):333-9. PubMed ID: 10655541
    [Abstract] [Full Text] [Related]

  • 12. A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology.
    Bowerman M, Murray LM, Beauvais A, Pinheiro B, Kothary R.
    Neuromuscul Disord; 2012 Mar 12; 22(3):263-76. PubMed ID: 22071333
    [Abstract] [Full Text] [Related]

  • 13. Proteomic assessment of a cell model of spinal muscular atrophy.
    Wu CY, Whye D, Glazewski L, Choe L, Kerr D, Lee KH, Mason RW, Wang W.
    BMC Neurosci; 2011 Mar 08; 12():25. PubMed ID: 21385431
    [Abstract] [Full Text] [Related]

  • 14. Shift from extracellular signal-regulated kinase to AKT/cAMP response element-binding protein pathway increases survival-motor-neuron expression in spinal-muscular-atrophy-like mice and patient cells.
    Branchu J, Biondi O, Chali F, Collin T, Leroy F, Mamchaoui K, Makoukji J, Pariset C, Lopes P, Massaad C, Chanoine C, Charbonnier F.
    J Neurosci; 2013 Mar 06; 33(10):4280-94. PubMed ID: 23467345
    [Abstract] [Full Text] [Related]

  • 15. Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy.
    Deguise MO, De Repentigny Y, Tierney A, Beauvais A, Michaud J, Chehade L, Thabet M, Paul B, Reilly A, Gagnon S, Renaud JM, Kothary R.
    EBioMedicine; 2020 May 06; 55():102750. PubMed ID: 32339936
    [Abstract] [Full Text] [Related]

  • 16. Skeletal muscle DNA damage precedes spinal motor neuron DNA damage in a mouse model of Spinal Muscular Atrophy (SMA).
    Fayzullina S, Martin LJ.
    PLoS One; 2014 May 06; 9(3):e93329. PubMed ID: 24667816
    [Abstract] [Full Text] [Related]

  • 17. Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy.
    Simon CM, Van Alstyne M, Lotti F, Bianchetti E, Tisdale S, Watterson DM, Mentis GZ, Pellizzoni L.
    Cell Rep; 2019 Dec 17; 29(12):3885-3901.e5. PubMed ID: 31851921
    [Abstract] [Full Text] [Related]

  • 18. Normalization of Patient-Identified Plasma Biomarkers in SMNΔ7 Mice following Postnatal SMN Restoration.
    Arnold WD, Duque S, Iyer CC, Zaworski P, McGovern VL, Taylor SJ, von Herrmann KM, Kobayashi DT, Chen KS, Kolb SJ, Paushkin SV, Burghes AH.
    PLoS One; 2016 Dec 17; 11(12):e0167077. PubMed ID: 27907033
    [Abstract] [Full Text] [Related]

  • 19. Reduced P53 levels ameliorate neuromuscular junction loss without affecting motor neuron pathology in a mouse model of spinal muscular atrophy.
    Courtney NL, Mole AJ, Thomson AK, Murray LM.
    Cell Death Dis; 2019 Jul 04; 10(7):515. PubMed ID: 31273192
    [Abstract] [Full Text] [Related]

  • 20. The zinc finger protein ZPR1 is a potential modifier of spinal muscular atrophy.
    Ahmad S, Wang Y, Shaik GM, Burghes AH, Gangwani L.
    Hum Mol Genet; 2012 Jun 15; 21(12):2745-58. PubMed ID: 22422766
    [Abstract] [Full Text] [Related]

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