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2. Synthesis and characterization of all four isomers of the muscarinic agonist 2'-methylspiro[1-azabicyclo[2.2.2]octane-3,4'-[1,3]dioxolane]. Saunders J, Showell GA, Baker R, Freedman SB, Hill D, McKnight A, Newberry N, Salamone JD, Hirshfield J, Springer JP. J Med Chem; 1987 Jun; 30(6):969-75. PubMed ID: 3585909 [Abstract] [Full Text] [Related]
3. Synthesis and SAR of bulky 1-azabicyclo[2.2.1]-3-one oximes as muscarinic receptor subtype selective agonists. Tecle H, Lauffer DJ, Mirzadegan T, Moos WH, Moreland DW, Pavia MR, Schwarz RD, Davis RE. Life Sci; 1993 Jun; 52(5-6):505-11. PubMed ID: 8382765 [Abstract] [Full Text] [Related]
4. In vitro down-regulation predicts agonist efficacy at central muscarinic cholinergic receptors. Stoll L, Müller WE. Biochem Pharmacol; 1991 Jun 15; 41(12):1963-6. PubMed ID: 2039547 [Abstract] [Full Text] [Related]
5. Muscarinic M3 receptors mediate total inositol phosphates accumulation in murine HSDM1C1 fibrosarcoma cells. Eglen RM, Sharif NA, To ZP. Eur J Pharmacol; 1993 Jan 04; 244(1):49-55. PubMed ID: 8420791 [Abstract] [Full Text] [Related]
6. Synthesis and muscarinic activities of 1,2,4-thiadiazoles. MacLeod AM, Baker R, Freedman SB, Patel S, Merchant KJ, Roe M, Saunders J. J Med Chem; 1990 Jul 04; 33(7):2052-9. PubMed ID: 2362286 [Abstract] [Full Text] [Related]
7. Conformationally restricted analogues of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide. Lundkvist JR, Ringdahl B, Hacksell U. J Med Chem; 1989 Apr 04; 32(4):863-9. PubMed ID: 2704032 [Abstract] [Full Text] [Related]
8. L-689,660, a novel cholinomimetic with functional selectivity for M1 and M3 muscarinic receptors. Hargreaves RJ, McKnight AT, Scholey K, Newberry NR, Street LJ, Hutson PH, Semark JE, Harley EA, Patel S, Freedman SB. Br J Pharmacol; 1992 Oct 04; 107(2):494-501. PubMed ID: 1422595 [Abstract] [Full Text] [Related]
15. Functionalized congener approach for the design of novel muscarinic agents. Synthesis and pharmacological evaluation of N-methyl-N-[4-(1-pyrrolidinyl)-2-butynyl] amides. Bradbury BJ, Baumgold J, Jacobson KA. J Med Chem; 1990 Feb 24; 33(2):741-8. PubMed ID: 2153827 [Abstract] [Full Text] [Related]
17. Analogues of the muscarinic agent 2'-methylspiro[1-azabicyclo[2.2.2]octane-3,4'-[1,3]dioxolane]: synthesis and pharmacology. Nordvall G, Sundquist S, Glas G, Gogoll A, Nilvebrant L, Hacksell U. J Med Chem; 1992 May 01; 35(9):1541-50. PubMed ID: 1578479 [Abstract] [Full Text] [Related]
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