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Journal Abstract Search

349 related items for PubMed ID: 33413202

  • 1. The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo.
    Grimes MM, Kenney SR, Dominguez DR, Brayer KJ, Guo Y, Wandinger-Ness A, Hudson LG.
    BMC Cancer; 2021 Jan 07; 21(1):40. PubMed ID: 33413202
    [Abstract] [Full Text] [Related]

  • 2. R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis.
    Guo Y, Kenney SR, Muller CY, Adams S, Rutledge T, Romero E, Murray-Krezan C, Prekeris R, Sklar LA, Hudson LG, Wandinger-Ness A.
    Mol Cancer Ther; 2015 Oct 07; 14(10):2215-27. PubMed ID: 26206334
    [Abstract] [Full Text] [Related]

  • 3. Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases.
    Oprea TI, Sklar LA, Agola JO, Guo Y, Silberberg M, Roxby J, Vestling A, Romero E, Surviladze Z, Murray-Krezan C, Waller A, Ursu O, Hudson LG, Wandinger-Ness A.
    PLoS One; 2015 Oct 07; 10(11):e0142182. PubMed ID: 26558612
    [Abstract] [Full Text] [Related]

  • 4. A Novel Pharmacologic Activity of Ketorolac for Therapeutic Benefit in Ovarian Cancer Patients.
    Guo Y, Kenney SR, Cook L, Adams SF, Rutledge T, Romero E, Oprea TI, Sklar LA, Bedrick E, Wiggins CL, Kang H, Lomo L, Muller CY, Wandinger-Ness A, Hudson LG.
    Clin Cancer Res; 2015 Nov 15; 21(22):5064-72. PubMed ID: 26071482
    [Abstract] [Full Text] [Related]

  • 5. Dual Actions of Ketorolac in Metastatic Ovarian Cancer.
    Hudson LG, Cook LS, Grimes MM, Muller CY, Adams SF, Wandinger-Ness A.
    Cancers (Basel); 2019 Jul 24; 11(8):. PubMed ID: 31344967
    [Abstract] [Full Text] [Related]

  • 6. The R-Enantiomer of Ketorolac Delays Mammary Tumor Development in Mouse Mammary Tumor Virus-Polyoma Middle T Antigen (MMTV-PyMT) Mice.
    Peretti AS, Dominguez D, Grimes MM, Hathaway HJ, Prossnitz ER, Rivera MR, Wandinger-Ness A, Kusewitt DF, Hudson LG.
    Am J Pathol; 2018 Feb 24; 188(2):515-524. PubMed ID: 29169987
    [Abstract] [Full Text] [Related]

  • 7. A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice.
    Zins K, Lucas T, Reichl P, Abraham D, Aharinejad S.
    PLoS One; 2013 Feb 24; 8(9):e74924. PubMed ID: 24040362
    [Abstract] [Full Text] [Related]

  • 8. Ketorolac modulates Rac-1/HIF-1α/DDX3/β-catenin signalling via a tumor suppressor prostate apoptosis response-4 (Par-4) in renal cell carcinoma.
    Sonawane V, Ghosalkar J, Achrekar S, Joshi K.
    Sci Rep; 2023 Apr 06; 13(1):5659. PubMed ID: 37024613
    [Abstract] [Full Text] [Related]

  • 9. BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study.
    Makrodouli E, Oikonomou E, Koc M, Andera L, Sasazuki T, Shirasawa S, Pintzas A.
    Mol Cancer; 2011 Sep 23; 10():118. PubMed ID: 21943101
    [Abstract] [Full Text] [Related]

  • 10. Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma.
    Kumar A, Al-Sammarraie N, DiPette DJ, Singh US.
    Oncotarget; 2014 Nov 30; 5(22):11709-22. PubMed ID: 25365944
    [Abstract] [Full Text] [Related]

  • 11. Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity.
    Zins K, Gunawardhana S, Lucas T, Abraham D, Aharinejad S.
    J Transl Med; 2013 Nov 27; 11():295. PubMed ID: 24279335
    [Abstract] [Full Text] [Related]

  • 12. Botulinum Toxin A Upregulates Rac1, Cdc42, and RhoA Gene Expression in a Dose-Dependent Manner: In Vivo and in Vitro Study.
    Park TH, Park JH, Chang CH, Rah DK.
    J Craniofac Surg; 2016 Mar 27; 27(2):516-20. PubMed ID: 26963302
    [Abstract] [Full Text] [Related]

  • 13. The role of vascular endothelial growth factor, interleukin 8, and insulinlike growth factor in sustaining autophagic DIRAS3-induced dormant ovarian cancer xenografts.
    Mao W, Peters HL, Sutton MN, Orozco AF, Pang L, Yang H, Lu Z, Bast RC.
    Cancer; 2019 Apr 15; 125(8):1267-1280. PubMed ID: 30620384
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of Ovarian Epithelial Carcinoma Tumorigenesis and Progression by microRNA 106b Mediated through the RhoC Pathway.
    Chen S, Chen X, Xiu YL, Sun KX, Zhao Y.
    PLoS One; 2015 Apr 15; 10(5):e0125714. PubMed ID: 25933027
    [Abstract] [Full Text] [Related]

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  • 16. Inhibition of cyclooxygenase-1 and -2 expression by targeting the endothelin a receptor in human ovarian carcinoma cells.
    Spinella F, Rosanò L, Di Castro V, Nicotra MR, Natali PG, Bagnato A.
    Clin Cancer Res; 2004 Jul 15; 10(14):4670-9. PubMed ID: 15269139
    [Abstract] [Full Text] [Related]

  • 17. Methylated dialkylphosphate metabolites of the organophosphate pesticide malathion modify actin cytoskeleton arrangement and cell migration via activation of Rho GTPases Rac1 and Cdc42.
    Hernández-Toledano DS, Vega L.
    Chem Biol Interact; 2023 Sep 01; 382():110593. PubMed ID: 37270087
    [Abstract] [Full Text] [Related]

  • 18. Rho family GTPases cooperate with p53 deletion to promote primary mouse embryonic fibroblast cell invasion.
    Guo F, Zheng Y.
    Oncogene; 2004 Jul 22; 23(33):5577-85. PubMed ID: 15122327
    [Abstract] [Full Text] [Related]

  • 19. Role of activated Rac1/Cdc42 in mediating endothelial cell proliferation and tumor angiogenesis in breast cancer.
    Ma J, Xue Y, Liu W, Yue C, Bi F, Xu J, Zhang J, Li Y, Zhong C, Chen Y.
    PLoS One; 2013 Jul 22; 8(6):e66275. PubMed ID: 23750283
    [Abstract] [Full Text] [Related]

  • 20. Different roles of the small GTPases Rac1, Cdc42, and RhoG in CALEB/NGC-induced dendritic tree complexity.
    Schulz J, Franke K, Frick M, Schumacher S.
    J Neurochem; 2016 Oct 22; 139(1):26-39. PubMed ID: 27412363
    [Abstract] [Full Text] [Related]

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