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Journal Abstract Search

177 related items for PubMed ID: 33438037

  • 1. When is an obscurin variant pathogenic? The impact of Arg4344Gln and Arg4444Trp variants on protein-protein interactions and protein stability.
    Fukuzawa A, Koch D, Grover S, Rees M, Gautel M.
    Hum Mol Genet; 2021 Jun 09; 30(12):1131-1141. PubMed ID: 33438037
    [Abstract] [Full Text] [Related]

  • 2. Deletion of obscurin immunoglobulin domains Ig58/59 leads to age-dependent cardiac remodeling and arrhythmia.
    Grogan A, Coleman A, Joca H, Granzier H, Russel MW, Ward CW, Kontrogianni-Konstantopoulos A.
    Basic Res Cardiol; 2020 Sep 10; 115(6):60. PubMed ID: 32910221
    [Abstract] [Full Text] [Related]

  • 3. Structural analysis of obscurin gene in hypertrophic cardiomyopathy.
    Arimura T, Matsumoto Y, Okazaki O, Hayashi T, Takahashi M, Inagaki N, Hinohara K, Ashizawa N, Yano K, Kimura A.
    Biochem Biophys Res Commun; 2007 Oct 19; 362(2):281-7. PubMed ID: 17716621
    [Abstract] [Full Text] [Related]

  • 4. Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.
    Bagnato P, Barone V, Giacomello E, Rossi D, Sorrentino V.
    J Cell Biol; 2003 Jan 20; 160(2):245-53. PubMed ID: 12527750
    [Abstract] [Full Text] [Related]

  • 5. Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin.
    Hu LR, Ackermann MA, Hecker PA, Prosser BL, King B, O'Connell KA, Grogan A, Meyer LC, Berndsen CE, Wright NT, Jonathan Lederer W, Kontrogianni-Konstantopoulos A.
    Sci Adv; 2017 Jun 20; 3(6):e1603081. PubMed ID: 28630914
    [Abstract] [Full Text] [Related]

  • 6. The rho-guanine nucleotide exchange factor domain of obscurin activates rhoA signaling in skeletal muscle.
    Ford-Speelman DL, Roche JA, Bowman AL, Bloch RJ.
    Mol Biol Cell; 2009 Sep 20; 20(17):3905-17. PubMed ID: 19605563
    [Abstract] [Full Text] [Related]

  • 7. The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system.
    Bang ML, Centner T, Fornoff F, Geach AJ, Gotthardt M, McNabb M, Witt CC, Labeit D, Gregorio CC, Granzier H, Labeit S.
    Circ Res; 2001 Nov 23; 89(11):1065-72. PubMed ID: 11717165
    [Abstract] [Full Text] [Related]

  • 8. Impaired Intracellular Ca2+ Dynamics, M-Band and Sarcomere Fragility in Skeletal Muscles of Obscurin KO Mice.
    Pierantozzi E, Szentesi P, Paolini C, Dienes B, Fodor J, Oláh T, Colombini B, Rassier DE, Rubino EM, Lange S, Rossi D, Csernoch L, Bagni MA, Reggiani C, Sorrentino V.
    Int J Mol Sci; 2022 Jan 24; 23(3):. PubMed ID: 35163243
    [Abstract] [Full Text] [Related]

  • 9. Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band: implications for hereditary myopathies.
    Fukuzawa A, Lange S, Holt M, Vihola A, Carmignac V, Ferreiro A, Udd B, Gautel M.
    J Cell Sci; 2008 Jun 01; 121(11):1841-51. PubMed ID: 18477606
    [Abstract] [Full Text] [Related]

  • 10. Novel OBSCN variants associated with a risk to exercise-intolerance and rhabdomyolysis.
    Zemorshidi F, Töpf A, Claeys KG, McFarlane A, Patton A, Nafissi S, Straub V.
    Neuromuscul Disord; 2024 Jan 01; 34():83-88. PubMed ID: 38159459
    [Abstract] [Full Text] [Related]

  • 11. Localization of ank1.5 in the sarcoplasmic reticulum precedes that of SERCA and RyR: relationship with the organization of obscurin in developing sarcomeres.
    Giacomello E, Sorrentino V.
    Histochem Cell Biol; 2009 Mar 01; 131(3):371-82. PubMed ID: 19002483
    [Abstract] [Full Text] [Related]

  • 12. Molecular interactions with obscurin are involved in the localization of muscle-specific small ankyrin1 isoforms to subcompartments of the sarcoplasmic reticulum.
    Armani A, Galli S, Giacomello E, Bagnato P, Barone V, Rossi D, Sorrentino V.
    Exp Cell Res; 2006 Nov 01; 312(18):3546-58. PubMed ID: 16962094
    [Abstract] [Full Text] [Related]

  • 13. The rho-guanine nucleotide exchange factor domain of obscurin regulates assembly of titin at the Z-disk through interactions with Ran binding protein 9.
    Bowman AL, Catino DH, Strong JC, Randall WR, Kontrogianni-Konstantopoulos A, Bloch RJ.
    Mol Biol Cell; 2008 Sep 01; 19(9):3782-92. PubMed ID: 18579686
    [Abstract] [Full Text] [Related]

  • 14. Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly.
    Young P, Ehler E, Gautel M.
    J Cell Biol; 2001 Jul 09; 154(1):123-36. PubMed ID: 11448995
    [Abstract] [Full Text] [Related]

  • 15. The crystal structure of the human titin:obscurin complex reveals a conserved yet specific muscle M-band zipper module.
    Pernigo S, Fukuzawa A, Pandini A, Holt M, Kleinjung J, Gautel M, Steiner RA.
    J Mol Biol; 2015 Feb 27; 427(4):718-736. PubMed ID: 25490259
    [Abstract] [Full Text] [Related]

  • 16. Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.
    Pernigo S, Fukuzawa A, Beedle AEM, Holt M, Round A, Pandini A, Garcia-Manyes S, Gautel M, Steiner RA.
    Structure; 2017 Jan 03; 25(1):107-120. PubMed ID: 27989621
    [Abstract] [Full Text] [Related]

  • 17. Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum.
    Lange S, Ouyang K, Meyer G, Cui L, Cheng H, Lieber RL, Chen J.
    J Cell Sci; 2009 Aug 01; 122(Pt 15):2640-50. PubMed ID: 19584095
    [Abstract] [Full Text] [Related]

  • 18. Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.
    Blondelle J, Marrocco V, Clark M, Desmond P, Myers S, Nguyen J, Wright M, Bremner S, Pierantozzi E, Ward S, Estève E, Sorrentino V, Ghassemian M, Lange S.
    Commun Biol; 2019 Aug 01; 2():178. PubMed ID: 31098411
    [Abstract] [Full Text] [Related]

  • 19. Obscurin regulates ankyrin macromolecular complex formation.
    Subramaniam J, Yamankurt G, Cunha SR.
    J Mol Cell Cardiol; 2022 Jul 01; 168():44-57. PubMed ID: 35447147
    [Abstract] [Full Text] [Related]

  • 20. Electrostatic interactions mediate binding of obscurin to small ankyrin 1: biochemical and molecular modeling studies.
    Busby B, Oashi T, Willis CD, Ackermann MA, Kontrogianni-Konstantopoulos A, Mackerell AD, Bloch RJ.
    J Mol Biol; 2011 Apr 29; 408(2):321-34. PubMed ID: 21333652
    [Abstract] [Full Text] [Related]

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