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189 related items for PubMed ID: 33450182
1. Cryo-EM Structure of K+-Bound hERG Channel Complexed with the Blocker Astemizole. Asai T, Adachi N, Moriya T, Oki H, Maru T, Kawasaki M, Suzuki K, Chen S, Ishii R, Yonemori K, Igaki S, Yasuda S, Ogasawara S, Senda T, Murata T. Structure; 2021 Mar 04; 29(3):203-212.e4. PubMed ID: 33450182 [Abstract] [Full Text] [Related]
5. Cryo-EM Structure of the Open Human Ether-à-go-go-Related K+ Channel hERG. Wang W, MacKinnon R. Cell; 2017 Apr 20; 169(3):422-430.e10. PubMed ID: 28431243 [Abstract] [Full Text] [Related]
7. Electrophysiological characterization of the modified hERGT potassium channel used to obtain the first cryo-EM hERG structure. Zhang Y, Dempsey CE, Hancox JC. Physiol Rep; 2020 Oct 20; 8(20):e14568. PubMed ID: 33091232 [Abstract] [Full Text] [Related]
13. Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant. Al-Moubarak E, Shiels HA, Zhang Y, Du C, Hanington O, Harmer SC, Dempsey CE, Hancox JC. Cell Mol Life Sci; 2021 Dec 20; 78(23):7899-7914. PubMed ID: 34727194 [Abstract] [Full Text] [Related]
14. Pharmacological separation of hEAG and hERG K+ channel function in the human mammary carcinoma cell line MCF-7. Roy J, Vantol B, Cowley EA, Blay J, Linsdell P. Oncol Rep; 2008 Jun 20; 19(6):1511-6. PubMed ID: 18497958 [Abstract] [Full Text] [Related]
16. Facilitation of IKr current by some hERG channel blockers suppresses early afterdepolarizations. Furutani K, Tsumoto K, Chen IS, Handa K, Yamakawa Y, Sack JT, Kurachi Y. J Gen Physiol; 2019 Feb 04; 151(2):214-230. PubMed ID: 30674563 [Abstract] [Full Text] [Related]
17. Dynamics of hERG closure allow novel insights into hERG blocking by small molecules. Schmidtke P, Ciantar M, Theret I, Ducrot P. J Chem Inf Model; 2014 Aug 25; 54(8):2320-33. PubMed ID: 25000969 [Abstract] [Full Text] [Related]
18. Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects. Zhou Z, Gong Q, January CT. J Biol Chem; 1999 Oct 29; 274(44):31123-6. PubMed ID: 10531299 [Abstract] [Full Text] [Related]
19. Computer Simulations Reveal a Novel Blocking Mode of the hERG Ion Channel by the Antiarrhythmic Agent Clofilium. Șterbuleac D, Maniu CL. Mol Inform; 2018 Jul 29; 37(6-7):e1700142. PubMed ID: 29465167 [Abstract] [Full Text] [Related]